Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Hiroaki Oniki"'
Autor:
Hiroko Kojima, Seiji Shibuya, Yoko Matsuzaki, Shoji Iijima, Takahiro Jimi, Hiroaki Oniki, Masahiko Inoue, Hajime Hara, Yoshihiro Wakayama, Hisatsugu Masaki
Publikováno v:
Journal of Molecular Histology. 40:165-170
The examination was performed whether aquaporin (AQP) 9 is expressed in normal skeletal muscle at mRNA and protein levels. Gel electrophoresis of the reverse transcription-polymerase chain reaction (RT-PCR) product of total RNA samples of human norma
Autor:
Yoshihiro Wakayama, Hiroaki Oniki, Kiyoko Nakano, Akihiko Unaki, Takahiro Jimi, Hajime Hara, Masahiko Inoue, Hisatsugu Masaki, Koji Kishimoto, Yoshiko Hirayama, Shoji Iijima
Publikováno v:
Journal of Molecular Histology. 40:117-121
Dysbindin was first identified by the yeast two hybrid assay as a binding partner of dystrobrevin which is a cytoplasmic member of dystrophin glycoprotein complex. Immunolocalization of dystrobrevin in the astrocyte endfeet and endothelial cells in t
Autor:
Mutsushi Matsuyama, Kiyoko Nakano, Kiyotaka Akiyama, Shiro Suetsugu, Noriko Wakisaka, Hiroyuki Morita, Seiko Kuraba, Yasuharu Numata, Kiyoko Inui, Hiroaki Oniki, Ashio Yoshimura, Terukuni Ideura, Yoshihisa Yamamoto, Tadaomi Takenawa
Publikováno v:
Mammalian Genome. 19:41-50
The BUF/Mna strain of rat is a model of focal and segmental glomerulosclerosis (FSGS) in which a quantitative trait locus (QTL) for proteinuria, Pur1, has been identified. The aim of the present study was to identify candidates for the Pur1 gene. To
Autor:
Seiji Shibuya, Hiroaki Oniki, Teruo Shimizu, Satoru Arata, Takahiro Jimi, Hiroko Ohi, Seiji Shioda, Joji Takahashi, Yoshihiro Wakayama, Masahiko Inoue, Hiroko Kojima, Yoshihide Sunada, Hajime Hara
Publikováno v:
Micron. 38:257-267
We generated the muscle aquaporin 4 (AQP4) overexpressing transgenic mice in order to investigate the skeletal muscle pathology at RNA and protein levels. At RNA level, the AQP4 mRNA expression of soleus, EDL and cardiac muscles in Tg mice was statis
Autor:
Yoko Matsuzaki, Hiroko Kojima, Hiroaki Oniki, Masahiko Inoue, Yoshihiro Wakayama, Joji Takahashi, Hajime Hara, Seiji Shibuya, Takahiro Jimi
Publikováno v:
Cells Tissues Organs. 184:181-187
To examine aquaporin 1 (AQP1) expression in skeletal muscle tissue precisely, we performed reverse transcription-polymerase chain reaction (RT-PCR) at RNA level and immunoblot analysis, immunohistochemistry and immunoelectron microscopy at protein le
Autor:
Hiroko Kojima, Masahiko Inoue, Hiroaki Oniki, Ichizo Nishino, Yoshihiro Wakayama, Seiji Shibuya, Takahiro Jimi, Ikuya Nonaka
Publikováno v:
The Tohoku Journal of Experimental Medicine. 209:109-116
Myoferlin is a novel protein of unknown function with high homology to dysferlin, the gene mutations of which cause limb girdle muscular dystrophy type 2B and Miyoshi myopathy. The myoferlin gene seems to be a candidate for the modifier, and because
Publikováno v:
Medical Molecular Morphology. 38:13-17
It is likely that orthogonal arrays (OAs) and caveolae seen on the replicas of freeze-fractured muscle plasma membranes are involved in maintaining osmotic homeostasis. Therefore, using the freeze-fracture technique, we examined the ultrastructural c
Publikováno v:
Medical Electron Microscopy. 36:59-65
Our previous freeze-fracture study demonstrated the decreased density of intramembranous particles (IMPs) on the protoplasmic (P) face of muscle plasma membranes in mdx mice. However, the molecular mechanism is unknown. In the present freeze-fracture
Publikováno v:
Neuroscience Letters. 325:171-174
To analyze the molecular mechanism of the increased caveolin 3 activities in dystrophin-deficient muscles, we investigated three-dimensionally the changes in caveolin 3 molecular distribution and density at the sarcolemma of mdx mice by the fracture-
Autor:
Seiji Shibuya, Masahiko Inoue, Hiroaki Oniki, Yoshihiro Wakayama, Hiroko Kojima, Takahiro Jimi, Makoto Murahashi, Hajime Hara
Publikováno v:
The Histochemical Journal. 34:331-337
The question whether aquaporin 3 (AQP3) is expressed in normal human skeletal muscle at mRNA and protein levels has been examined, since AQP3 has been reported to be coexpressed with AQP4 in various kinds of tissues other than skeletal muscle. The ge