Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Hiroaki Mohri"'
Publikováno v:
Neurobiology of Disease, Vol 186, Iss , Pp 106280- (2023)
Considerable evidence of reactive oxygen species (ROS) involvement in cochlear hair cell (HC) loss, leading to acquired sensorineural hearing loss (SNHL), were reported. Cochlear synaptopathy between HCs and spiral ganglion neurons has been gathering
Externí odkaz:
https://doaj.org/article/13ce5f34d3c84c8ba56e5d032842d681
Publikováno v:
Journal of International Advanced Otology, Vol 17, Iss 5, Pp 465-467 (2021)
Externí odkaz:
https://doaj.org/article/54a07b57b0aa4d1eaf78b179897750b4
Autor:
Shigefumi Morioka, Hirofumi Sakaguchi, Hiroaki Mohri, Mariko Taniguchi-Ikeda, Motoi Kanagawa, Toshiaki Suzuki, Yuko Miyagoe-Suzuki, Tatsushi Toda, Naoaki Saito, Takehiko Ueyama
Publikováno v:
PLoS Genetics, Vol 16, Iss 5, p e1008826 (2020)
Hearing loss (HL) is one of the most common sensory impairments and etiologically and genetically heterogeneous disorders in humans. Muscular dystrophies (MDs) are neuromuscular disorders characterized by progressive degeneration of skeletal muscle a
Externí odkaz:
https://doaj.org/article/e459f0bf0deb4f4bba4537cab949d556
Autor:
Jun-ichi Takeshita, Hiroaki Mohri
Publikováno v:
Journal of Risk Analysis and Crisis Response (JRACR), Vol 4, Iss 1 (2013)
The principal aim of this paper is to introduce the framework for a cooperative game theoretical approach to risk analysis using network structure. Probabilistic risk analysis (PRA) is a common methodology for evaluating risks associated with real-wo
Externí odkaz:
https://doaj.org/article/dd4789eaa75c4262b3843f3602a008d2
Autor:
Takashi Nakamura, Hirofumi Sakaguchi, Hiroaki Mohri, Yuzuru Ninoyu, Akihiro Goto, Taro Yamaguchi, Yoshitaka Hishikawa, Michiyuki Matsuda, Naoaki Saito, Takehiko Ueyama
Publikováno v:
Journal of Molecular Medicine.
Abstract Rac small GTPases play important roles during embryonic development of the inner ear; however, little is known regarding their function in cochlear hair cells (HCs) after specification. Here, we revealed the localization and activation of Ra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f81b9b132b6fa4fa6c495a333b29b37
https://doi.org/10.1007/s00109-023-02317-4
https://doi.org/10.1007/s00109-023-02317-4
Autor:
Shigeru Hirano, Hiroaki Mohri, Hirofumi Sakaguchi, Yuzuru Ninoyu, Naoaki Saito, Takehiko Ueyama
Publikováno v:
The Journal of Neuroscience
Reactive oxygen species (ROS) produced by NADPH oxidases (Nox) contribute to the development of different types of sensorineural hearing loss (SNHL), a common impairment in humans with no established treatment. Although the essential role of Nox3 in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::229a062cf7cee3f3469f265fda6aa55a
https://hdl.handle.net/20.500.14094/90008398
https://hdl.handle.net/20.500.14094/90008398
Publikováno v:
Journal of International Advanced Otology, Vol 17, Iss 5, Pp 465-467 (2021)
Past studies have found an association between cochlear hydrops or early Meniere's disease and acute low-frequency hearing loss (ALHL) without vertigo. However, its mechanism remains unclear in some ALHL cases. This report presents a case of ALHL ass
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::997bc36820bb11979d45f2a9fa1c65d7
https://pubmed.ncbi.nlm.nih.gov/34617900
https://pubmed.ncbi.nlm.nih.gov/34617900
Autor:
Yuko Miyagoe-Suzuki, Takehiko Ueyama, Motoi Kanagawa, Hiroaki Mohri, Mariko Taniguchi-Ikeda, Shigefumi Morioka, Hirofumi Sakaguchi, Naoaki Saito, Tatsushi Toda, Toshiaki Suzuki
Publikováno v:
PLoS Genetics, Vol 16, Iss 5, p e1008826 (2020)
PLoS Genetics
PLoS Genetics
Hearing loss (HL) is one of the most common sensory impairments and etiologically and genetically heterogeneous disorders in humans. Muscular dystrophies (MDs) are neuromuscular disorders characterized by progressive degeneration of skeletal muscle a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd003f189f1725ee5683f1462ea13cc6
https://doaj.org/article/e459f0bf0deb4f4bba4537cab949d556
https://doaj.org/article/e459f0bf0deb4f4bba4537cab949d556
Autor:
Kiyokazu Ogita, Hirofumi Sakaguchi, Hiroaki Mohri, Yuzuru Ninoyu, Shigefumi Morioka, Yasuo Hisa, Takashi Nakamura, Taro Yamaguchi, Takehiko Ueyama, Naoaki Saito
Publikováno v:
Journal of Neurochemistry. 146(4):459-473
Previous studies have convincingly argued that reactive oxygen species (ROS) contribute to the development of several major types of sensorineural hearing loss, such as noise-induced hearing loss (NIHL), drug-induced hearing loss, and age-related hea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f141d599d4e274e95246c982c8e2da1
https://hdl.handle.net/20.500.14094/90005448
https://hdl.handle.net/20.500.14094/90005448
Autor:
Chihiro Tohda, Takehiko Ueyama, Naoaki Saito, Michiko Shigyo, Takashi Nakamura, Isao Sakamoto, Hiroshi Kiyonari, Masakazu Hayashibe, Hiroaki Mohri
Publikováno v:
Experimental Neurology. 302:57-67
Bergmann glia (BG) are important in the inward type of radial migration of cerebellar granule neurons (CGNs). However, details regarding the functions of Cdc42 and Rac in BG for radial migration of CGN are unknown. To examine the roles of Cdc42 and R
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c86a7fa66f178b3fd4c022865bf560d8
https://hdl.handle.net/20.500.14094/90006402
https://hdl.handle.net/20.500.14094/90006402