Zobrazeno 1 - 10
of 93
pro vyhledávání: '"Hiroaki Matsubayashi"'
Autor:
Taku Amano, Zhu Aihua, Hiroaki Matsubayashi, Takahiro Seki, Tadao Serikawa, Masashi Sasa, Norio Sakai
Publikováno v:
Journal of Pharmacological Sciences, Vol 95, Iss 3, Pp 355-362 (2004)
We investigated the effects of single and repeated administrations of S-312-d (methyl-4,7-dihydro-3-isobutyl-6-methyl-4-(3-nitrophenyl)-thieno-[2,3-b]pyridine-5-carboxylate), a newly synthesized L-type Ca2+-channel blocker, on tonic convulsions and a
Externí odkaz:
https://doaj.org/article/e87b11ef036a49f1816b22ad3dd62509
Publikováno v:
Journal of Pharmacological Sciences, Vol 93, Iss 1, Pp 114-117 (2003)
ABSTRACT: To investigate the effect of cis-N-[4-[4-(1,2-benz-isozole-3-yl)-1-piperazinyl]butyl] cyclohexane-1,2-dicarboximide hydrochloride (perospirone), a novel antipsychotic agent with high affinities for D2/5-HT2 receptors, on the rat dorsal raph
Externí odkaz:
https://doaj.org/article/7be5b5f737984d3690e15fc8fa528018
Publikováno v:
Journal of Pharmacological Sciences, Vol 93, Iss 2, Pp 143-148 (2003)
ABSTRACT: The electrophysiological characteristics of nicotine-induced excitation of dopaminergic neurons in the rat substantia nigra was investigated using the whole-cell patch clamp technique under the voltage-clamp mode. Nicotine (0.01 – 100 μM
Externí odkaz:
https://doaj.org/article/189fbea01acf43d5b404dc906d67d4e2
Autor:
Shinichi Kohsaka, Hiroaki Matsubayashi, Izumi Hide, Kanako Miyano, Kazuhide Inoue, Kana Harada, Tomohisa Suzuki, Yoshihiro Nakata, Akiyo Matsubara, Norio Sakai, Chihiro Hama, Matthias Andrä
Publikováno v:
Journal of Neuroscience Research. 83:1461-1470
Microglia perform both neuroprotective and neurotoxic functions in the brain, with this depending on their state of activation and their release of mediators. Upon P2X(7) receptor stimulation, for example, microglia release small amounts of TNF, whic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::993ccd42fda1f220c7180c1aae6f810a
https://doi.org/10.1002/jnr.20850
https://doi.org/10.1002/jnr.20850
Autor:
Hideki Mochizuki, Hideshi Kawakami, Norio Sakai, Keiko Hiramoto, Naoaki Saito, Hiroaki Matsubayashi, Takahiro Seki, Yoshitaka Ono, Masayasu Matsumoto, Taku Amano, Naoko Adachi
Publikováno v:
Journal of Biological Chemistry. 280:29096-29106
Spinocerebellar ataxia type 14 (SCA14) is an autosomal dominant neurodegenerative disease characterized by various symptoms including cerebellar ataxia. Recently, several missense mutations in the protein kinase Cgamma (gammaPKC) gene have been found
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32ae73d2f7cbeead2de643e5f37f7b6d
https://doi.org/10.1074/jbc.m501716200
https://doi.org/10.1074/jbc.m501716200
Autor:
Taku Amano, Takahiro Seki, Hiroaki Matsubayashi, Norio Sakai, Toshihiro Dohi, Hideki Mochizuki, Hiromu K. Mishima, Shigeo Kitayama, Chieko Mitsuhata, Katsuya Morita
Publikováno v:
Neurochemistry International. 46:93-105
Previously, we revealed that the state of the actin cytoskeleton affects the uptake activity of the serotonin transporter (SERT). Recently, it was reported that the C-terminus of SERT interacts with MacMARCKS, a substrate of PKC that can bind to the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b3a871672566c6eb99c378d72b2abea
https://doi.org/10.1016/j.neuint.2004.08.008
https://doi.org/10.1016/j.neuint.2004.08.008
Publikováno v:
Folia Pharmacologica Japonica. 126:35-42
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fa174cd451c38e4943f6e846e2247408
https://doi.org/10.1254/fpj.126.35
https://doi.org/10.1254/fpj.126.35
Autor:
Norio Sakai, Eri Takahashi, Yasuhito Shirai, Hiroaki Matsubayashi, Masanori Matsuzaki, Hiroshi Tsubokawa, Shiho Ohmori, Yi Ren, Ronald S. Duman, Jingshan Chen, Naoaki Saito, Taketoshi Kajimoto, Haruo Kasai
Publikováno v:
Genes to Cells. 9:945-957
To elucidate spatial and temporal profiles of the protein kinase C (PKC) activation in relation to neuronal functions including synaptic plasticity, we tried to detect PKC translocation in living brain slices. We first developed brain region-specific
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::60d4d4bc8ee42c648a0a489e6c6a4a4b
https://doi.org/10.1111/j.1365-2443.2004.00779.x
https://doi.org/10.1111/j.1365-2443.2004.00779.x
Autor:
Zhu Aihua, Hiroaki Matsubayashi, Norio Sakai, Masashi Sasa, Taku Amano, Takahiro Seki, Tadao Serikawa
Publikováno v:
Journal of Pharmacological Sciences, Vol 95, Iss 3, Pp 355-362 (2004)
We investigated the effects of single and repeated administrations of S-312-d (methyl-4,7-dihydro-3-isobutyl-6-methyl-4-(3-nitrophenyl)-thieno-[2,3-b]pyridine-5-carboxylate), a newly synthesized L-type Ca2+-channel blocker, on tonic convulsions and a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5075b671096bfe0730d16bab0b55b105
https://doi.org/10.1254/jphs.fp0040233
https://doi.org/10.1254/jphs.fp0040233
Publikováno v:
Journal of Pharmacological Sciences, Vol 93, Iss 2, Pp 143-148 (2003)
The electrophysiological characteristics of nicotine-induced excitation of dopaminergic neurons in the rat substantia nigra was investigated using the whole-cell patch clamp technique under the voltage-clamp mode. Nicotine (0.01 - 100 microM) induced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5191d66e9b812c420e0d6ed95ee64ee
http://www.sciencedirect.com/science/article/pii/S1347861319325903
http://www.sciencedirect.com/science/article/pii/S1347861319325903