Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Hiroaki Magotani"'
Autor:
Daisuke Doi, Hiroaki Magotani, Tetsuhiro Kikuchi, Megumi Ikeda, Satoe Hiramatsu, Kenji Yoshida, Naoki Amano, Masaki Nomura, Masafumi Umekage, Asuka Morizane, Jun Takahashi
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Induced pluripotent stem cell (iPSC) derived dopaminergic neurons are a promising source for cell-based Parkinson’s disease (PD) therapy. Here the authors report a comprehensive pre-clinical evaluation of the safety and efficacy of dopaminergic pro
Externí odkaz:
https://doaj.org/article/a254d73774aa46918b7ca259baa03c3a
Autor:
Asuka Morizane, Tetsuhiro Kikuchi, Masaki Nomura, Jun Takahashi, Hiramatsu Satoe, Masafumi Umekage, Daisuke Doi, Megumi Ikeda, Yoshida Kenji, Hiroaki Magotani, Naoki Amano
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Nature Communications
Nature Communications
Induced pluripotent stem cell (iPSC)-derived dopaminergic (DA) neurons are an expected source for cell-based therapies for Parkinson’s disease (PD). The regulatory criteria for the clinical application of these therapies, however, have not been est
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::049b67163b975115b9c62c55238a0161
http://link.springer.com/article/10.1038/s41467-020-17165-w
http://link.springer.com/article/10.1038/s41467-020-17165-w
Autor:
Tetsuhiro Kikuchi, Satoshi Morita, Asuka Morizane, Takuya Hayashi, Hirotaka Onoe, Jun Takahashi, Sayuki Takara, Haruhisa Inoue, Hiroaki Magotani, Masato Nakagawa, Keisuke Okita, Michio Yamamoto, Malin Parmar, Daisuke Doi, Ryosuke Takahashi, Hiroshi Mizuma
Publikováno v:
Nature. 548:592-596
Induced pluripotent stem cells (iPS cells) are a promising source for a cell-based therapy to treat Parkinson's disease (PD), in which midbrain dopaminergic neurons progressively degenerate. However, long-term analysis of human iPS cell-derived dopam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::be24825b51f8d2e188b59c813cc2812d
https://doi.org/10.1038/nature23664
https://doi.org/10.1038/nature23664
Autor:
Toshiki Fujii, Makoto Miyazaki, Kazunori Iwanaga, Hiroaki Magotani, Masawo Kakemi, Nobuhiro Takeda
Publikováno v:
Drug Metabolism and Pharmacokinetics. 26:503-515
The circadian relationship between the pharmacokinetics and pharmacodynamics of tolbutamide in rats was analyzed using a compartment model. The basal concentration of plasma glucose had a circadian rhythm with the acrophase at 15:19 h. After intraven
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33eff5548b49e6c9294b3e331405621c
https://doi.org/10.2133/dmpk.dmpk-11-rg-021
https://doi.org/10.2133/dmpk.dmpk-11-rg-021