Zobrazeno 1 - 10
of 417
pro vyhledávání: '"Hiroaki Konishi"'
Autor:
Keita Kojima, Hiroaki Konishi, Kyoka Momosaki, Yuya Komatani, Akira Katsuyama, Koji Nakagawa, Kayoko Kanamitsu, Fumika Yakushiji, Mikihiro Fujiya, Satoshi Ichikawa
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-18 (2024)
Abstract Colorectal cancer is the third most commonly diagnosed cancer and the second leading cause of cancer-related death, thus a novel chemotherapeutic agent for colon cancer therapy is needed. In this study, analogues of echinomycin, a cyclic pep
Externí odkaz:
https://doaj.org/article/aa02e54da3b74ef795298246fa26c2d7
Autor:
Takehito Kunogi, Hiroaki Konishi, Aki Sakatani, Kentaro Moriichi, Chikage Yamamura, Koji Yamamoto, Shin Kashima, Katsuyoshi Ando, Nobuhiro Ueno, Hiroki Tanaka, Toshikatsu Okumura, Mikihiro Fujiya
Publikováno v:
Heliyon, Vol 10, Iss 6, Pp e28070- (2024)
Esophageal cancer, which is common among the elderly, has the poorest prognosis among gastrointestinal cancers. Previously, we demonstrated that ferrichrome, produced by the probiotic Lactobacillus casei, exhibited anti-tumor effects in various gastr
Externí odkaz:
https://doaj.org/article/7b9b38282a564fbdb545812570e9727c
Autor:
Yukio Ando, Marcia Waddington-Cruz, Yoshiki Sekijima, Haruki Koike, Mitsuharu Ueda, Hiroaki Konishi, Tomonori Ishii, Teresa Coelho
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 18, Iss 1, Pp 1-17 (2023)
Abstract Hereditary transthyretin (ATTRv) amyloidosis is a rare and autosomal dominant disorder associated with mutations in the transthyretin gene. Patients present with diverse symptoms related to sensory, motor, and autonomic neuropathy, as well a
Externí odkaz:
https://doaj.org/article/b4211bad5c5b4a2f92847c0a1e464bdc
Autor:
Fumitake Tezuka, Toshinori Sakai, Shiro Imagama, Hiroshi Takahashi, Masashi Takaso, Toshimi Aizawa, Koji Otani, Shinya Okuda, Satoshi Kato, Tokumi Kanemura, Yoshiharu Kawaguchi, Hiroaki Konishi, Kota Suda, Hidetomi Terai, Kazuo Nakanishi, Kotaro Nishida, Masaaki Machino, Naohisa Miyakoshi, Hideki Murakami, Yu Yamato, Yasutsugu Yukawa, Medical Safety Promotion Committee of The Japanese Society for Spine Surgery and Related Research
Publikováno v:
Spine Surgery and Related Research, Vol 7, Iss 5, Pp 428-435 (2023)
Introduction: The number of patients on antithrombotic drugs for coronary heart disease or cerebrovascular disease has been increasing with the aging of society. We occasionally need to decide whether to continue or discontinue antithrombotic drugs b
Externí odkaz:
https://doaj.org/article/d6b75559a7244ee1b8e49a7bacd7899f
Autor:
Eiji Nakata, Khongorzul Gerelbaatar, Mashal Asif, Hiroaki Konishi, Yuya Shibano, Peng Lin, Takashi Morii
Publikováno v:
Chemistry, Vol 5, Iss 3, Pp 1832-1842 (2023)
The desirable properties of the sophisticated fluorescent pH probe are ratiometric detection properties and a wide detection range. In this study, three types of fluorophores with different fluorescence properties were assembled on a DNA origami nano
Externí odkaz:
https://doaj.org/article/eed6f00e10d847e49239e9b5fec00ec6
Autor:
Yuki Murakami, Hiroaki Konishi, Mikihiro Fujiya, Keitaro Takahashi, Katsuyoshi Ando, Nobuhiro Ueno, Shin Kashima, Kentaro Moriichi, Hiroki Tanabe, Toshikatsu Okumura
Publikováno v:
Cancer Medicine, Vol 11, Iss 19, Pp 3643-3656 (2022)
Abstract Various heterogeneous nuclear ribonucleoproteins (hnRNPs) have been reported to be associated with cancer cell growth. However, it remains unclear whether hnRNP G‐T, which is specifically expressed in the testis, is expressed in tumor cell
Externí odkaz:
https://doaj.org/article/24a5d8a752554fc8b39a08fdb4ecebf5
Autor:
Shotaro Isozaki, Hiroaki Konishi, Hiroki Tanaka, Chikage Yamamura, Kentaro Moriichi, Naoki Ogawa, Mikihiro Fujiya
Publikováno v:
BMC Microbiology, Vol 22, Iss 1, Pp 1-9 (2022)
Abstract Background Several microorganisms inhabit the mammalian gastrointestinal tract and are associated with the pathogenesis of various diseases, including cancer. Recent studies have indicated that several probiotics produce antitumor molecules
Externí odkaz:
https://doaj.org/article/40ea23172ced443d92890af81a40670e
Autor:
Alex Q. Lee, Hiroaki Konishi, Connie Duong, Sakiko Yoshida, Ryan R. Davis, Jonathan E. Van Dyke, Masami Ijiri, Bridget McLaughlin, Kyoungmi Kim, Yueju Li, Laurel Beckett, Nitin Nitin, John D. McPherson, Clifford G. Tepper, Noriko Satake
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
In leukemia, a distinct subpopulation of cancer-initiating cells called leukemia stem cells (LSCs) is believed to drive population expansion and tumor growth. Failing to eliminate LSCs may result in disease relapse regardless of the amount of non-LSC
Externí odkaz:
https://doaj.org/article/65345325b8c3492586a08bddfb989d5c
Autor:
Hiroaki Konishi, Shotaro Isozaki, Shin Kashima, Kentaro Moriichi, Satoshi Ichikawa, Kazuki Yamamoto, Chikage Yamamura, Katsuyoshi Ando, Nobuhiro Ueno, Hiroaki Akutsu, Naoki Ogawa, Mikihiro Fujiya
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Intake of probiotics or fermented food produced by some probiotic bacteria is believed to exert anti-tumor functions in various cancers, including pancreatic cancer, because several studies have demonstrated the anti-tumor effects of probiot
Externí odkaz:
https://doaj.org/article/cfb8f92149174db3bf6dd9dbd49d3505
Autor:
Yasuhiro Takabayashi, Koji Kimura, Hiroaki Konishi, Taketoshi Minato, Reiji Takekawa, Tomotaka Nakatani, So Fujinami, Takeshi Abe, Kouichi Hayashi
Publikováno v:
Advanced Energy & Sustainability Research, Vol 3, Iss 7, Pp n/a-n/a (2022)
Fluoride shuttle batteries (FSBs) are superior to lithium‐ion batteries (LIBs) in terms of high energy density, safety, etc. An electrolyte consisting of tetraglyme (G4) as a solvent molecule and triphenylboroxine (TPhBX) as an anion acceptor to im
Externí odkaz:
https://doaj.org/article/e1379e786c9b49aeb307d44e090eab3f