Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Hiroaki Kii"'
Autor:
Jeonghoon Choi, Hiroaki Kii, Justin Nelson, Yoichi Yamazaki, Fumiki Yanagawa, Atsushi Kitajima, Takayuki Uozumi, Yasujiro Kiyota, Dimple Doshi, Kenneth Rhodes, Robert Scannevin, Heather Sadlish, Chee Yeun Chung
Publikováno v:
SLAS Technology, Vol 28, Iss 2, Pp 63-69 (2023)
The development of phenotypic assays with appropriate analyses is an important step in the drug discovery process. Assays using induced pluripotent stem cell (iPSC)-derived human neurons are emerging as powerful tools for drug discovery in neurologic
Externí odkaz:
https://doaj.org/article/718216d2882f4578a15d3fa8eb3f2afb
Autor:
Risako Nagasaka, Megumi Matsumoto, Mai Okada, Hiroto Sasaki, Kei Kanie, Hiroaki Kii, Takayuki Uozumi, Yasujiro Kiyota, Hiroyuki Honda, Ryuji Kato
Publikováno v:
Regenerative Therapy, Vol 6, Iss C, Pp 41-51 (2017)
From the recent advances, there are growing expectations toward the mass production of induced pluripotent stem cells (iPSCs) for varieties of applications. For such type of industrial cell manufacturing, the technology which can stabilize the produc
Externí odkaz:
https://doaj.org/article/f474e127784e4b488cdb2eceab66ecac
Autor:
Mika Suga, Takako Nakano, Takayuki Uozumi, Yasujiro Kiyota, Hiroaki Kii, Dan Tomoro, Miho Furue, Yujung Liu, Naoko Ueda
Publikováno v:
The International Journal of Developmental Biology. 62:613-621
Cell morphology is recognized as an important hallmark of neural cells. During the differentiation of human pluripotent stem cells (hPSCs) into neural cells, cell morphology changes dynamically. Therefore, characterization of the morphology of cells
Autor:
Hiroaki Kii, Mai Okada, Takayuki Uozumi, Ryuji Kato, Yasujiro Kiyota, Hiroyuki Honda, Kei Kanie, Megumi Matsumoto, Risako Nagasaka, Hiroto Sasaki
Publikováno v:
Regenerative Therapy, Vol 6, Iss C, Pp 41-51 (2017)
From the recent advances, there are growing expectations toward the mass production of induced pluripotent stem cells (iPSCs) for varieties of applications. For such type of industrial cell manufacturing, the technology which can stabilize the produc
Autor:
Hirotada Watanabe, Hiroaki Kii, Masahiro Tsuboi, Atsushi Ochiai, Takeshi Kuwata, Genichiro Ishii, Hiroko Hashimoto, Hiroshi Date, Kenkichi Masutomi, Koichi Goto, Shinya Neri
Publikováno v:
Journal of Cancer Research and Clinical Oncology. 142:437-446
As one form of tumor invasion, cancer cells can invade the extracellular matrix (ECM) through tracks that have been physically remodeled by cancer-associated fibroblasts (CAFs). However, CAFs are a heterogeneous population with diverse matrix-remodel
Autor:
Hiroko Hashimoto, Shinya Neri, Masahiro Tsuboi, Yoshitaka Suda, Hiroaki Kii, Hiroshi Date, Atsushi Ochiai, Genichiro Ishii, Takeshi Kuwata, Makoto Sonobe, Masayuki Ishibashi, Tomoyuki Miyashita, Hirotada Watanabe, Toshi Menju, Koichi Goto
Publikováno v:
Cancer letters. 395
Cancer-associated fibroblast (CAF)-dependent local invasion is the process by which cancer cells invade the extracellular matrix using tracks that have been physically remodeled by CAFs. In the present study, we investigated the process by which the
Autor:
Masayuki Murata, Hiroaki Kii, Fumi Kano, Daiki Nakatsu, Nobuhiko Maiya, Atsuhiro Adachi, Taichi Sugawara, Akitsugu Yamamoto
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1823(4):861-875
The ER–Golgi intermediate compartment (ERGIC) is an organelle through which cargo proteins pass and are being transferred by either anterograde or retrograde transport between the endoplasmic reticulum (ER) and the Golgi apparatus. We examined the
Autor:
Takao Nakamura, Yasutomo Nomura, Hirobumi Fuchigami, Zhonggang Feng, Hiroaki Kii, Masataka Kinjo
Publikováno v:
Experimental and Molecular Pathology. 80:275-278
A crucial investigation is to quantify restriction fragment length polymorphisms without gel electrophoresis, as the distribution of fragment size is mainly evaluated on the gel, which cannot be easily quantified. We developed a method to determine t
Autor:
Hirobumi Fuchigami, Masataka Kinjo, Takao Nakamura, Hiroaki Kii, Yasutomo Nomura, Zhonggang Feng
Publikováno v:
Analytical Biochemistry. 350:196-201
Using fluorescence correlation spectroscopy (FCS), we tested the feasibility of rapid detection of oxidative damage of mitochondrial DNA (mtDNA) in a small volume. The complete mtDNA genome was amplified by long polymerase chain reaction (LPCR), and
Autor:
Per Thyberg, Eckhard Birch-Hirschfeld, Ulrike Demel, Mamoru Tamura, Takuya Takagi, Gernot P. Tilz, Jean M Costa, Hiroaki Kii, Kenta Saito, Zeno Földes-Papp, Masataka Kinjo
Publikováno v:
Experimental and Molecular Pathology. 76:212-218
Whole blood samples of known methylene tetrahydrofolate reductase (MTHFR) genotypes from 24 individuals were examined at site C677T. Their amplified DNA products were assessed by two-color fluorescence cross-correlation measurements and agarose gel e