Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Hiroaki Kaku"'
Publikováno v:
Free Neuropathology, Vol 5 (2024)
The development and optimization of the Filter Trap Assay (FTA) for the detection of authentic tau fibrils in vitro mark a pivotal advancement in the realm of tauopathy research, particularly by addressing the limitations of using polyanion-induced t
Externí odkaz:
https://doaj.org/article/df2a3d9c2ce14a4d9952150c10400678
Autor:
Allison R Balaj, Hiroaki Kaku
Publikováno v:
Neural Regeneration Research, Vol 19, Iss 12, Pp 2577-2578 (2024)
Externí odkaz:
https://doaj.org/article/27acb26e94754fb2ba93d64ff30220dd
Autor:
Allison R Balaj, Hiroaki Kaku
Publikováno v:
Neural Regeneration Research, Vol 18, Iss 12, Pp 2677-2679 (2023)
Externí odkaz:
https://doaj.org/article/c0eff8364fab40f388d540daf3380b26
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 14 (2021)
A number of neurodegenerative diseases are associated with the accumulation of misfolded proteins, including Alzheimer’s disease (AD). In AD, misfolded proteins such as tau and amyloid-β (Aβ) form pathological insoluble deposits. It is hypothesiz
Externí odkaz:
https://doaj.org/article/8a310473c0d641f4bf602a19a4e24507
Autor:
Balaj, Allison R., Hiroaki Kaku
Publikováno v:
Neural Regeneration Research; Dec2023, Vol. 18 Issue 12, p2677-2679, 3p
Autor:
Balaj, Allison R., Hiroaki Kaku
Publikováno v:
Neural Regeneration Research; Dec2024, Vol. 19 Issue 12, p2577-2578, 2p
Autor:
Hiroaki Kaku, Thomas L. Rothstein
Publikováno v:
Frontiers in Molecular Biosciences, Vol 7 (2020)
A key element of cellular homeostasis lies in the way in which misfolded and dysfunctional proteins are handled. Cellular pathways that include proteasomal destruction and autophagic disposal are components of normal proteostasis. Here we report a no
Externí odkaz:
https://doaj.org/article/a80d5af199c34585aa859a0b059f0d4c
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2020)
Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative illness that is unremittingly fatal and for which no effective treatment exists. All forms of ALS are characterized by protein aggregation. In familial forms of ALS, specific and
Externí odkaz:
https://doaj.org/article/3d3ad6fd17ea4f73ba2b1fef5e48b677
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
B-1a cells are innate-like B-lymphocytes producing natural antibodies. Activation-induced cytidine deaminase (AID), a product of the Aicda gene, plays a central role in class-switch recombination and somatic hypermutation in B cells. Although a role
Externí odkaz:
https://doaj.org/article/0ab3307d121340608f610d4b4196848f
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 19; Pages: 11841
Cells and tissues are continuously subject to environmental insults, such as heat shock and oxidative stress, which cause the accumulation of cytotoxic, aggregated proteins. We previously found that Fas Apoptosis Inhibitory Molecule (FAIM) protects c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89464c44818b9741fb3baec8ec9345a9
https://pubmed.ncbi.nlm.nih.gov/36233145
https://pubmed.ncbi.nlm.nih.gov/36233145