Zobrazeno 1 - 10
of 309
pro vyhledávání: '"Hiroaki KURODA"'
Autor:
Yosuke Chiba, Tomomitsu Doi, Kunie Obayashi, Kazuhiro Sumida, Shohei Nagasaka, Ke-Yong Wang, Kei Yamasaki, Katsuhiro Masago, Hirokazu Matsushita, Hiroaki Kuroda, Kazuhiro Yatera, Motoyoshi Endo
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-14 (2024)
Abstract Caspase-4 (CASP4) is a member of the inflammatory caspase subfamily and promotes inflammation. Here, we report that CASP4 in lung adenocarcinoma cells contributes to both tumor progression via angiogenesis and tumor hyperkinesis and tumor ce
Externí odkaz:
https://doaj.org/article/ff46145806814e5e9d3f9110483eb902
Autor:
Yusuke Sugita, Daisuke Muraoka, Ayako Demachi-Okamura, Hiroyasu Komuro, Katsuhiro Masago, Eiichi Sasaki, Yasunori Fukushima, Takuya Matsui, Shuichi Shinohara, Yusuke Takahashi, Reina Nishida, Chieko Takashima, Teppei Yamaguchi, Yoshitsugu Horio, Kana Hashimoto, Ichidai Tanaka, Hiroshi Hamana, Hiroyuki Kishi, Daiki Miura, Yuki Tanaka, Kousuke Onoue, Kazuhide Onoguchi, Yoshiko Yamashita, Richard Stratford, Trevor Clancy, Rui Yamaguchi, Hiroaki Kuroda, Hironori Ishibashi, Kenichi Okubo, Hirokazu Matsushita
Publikováno v:
OncoImmunology, Vol 13, Iss 1 (2024)
Isolation of tumor-specific T cells and their antigen receptors (TCRs) from malignant pleural effusions (MPE) may facilitate the development of TCR-transduced adoptive cellular immunotherapy products for advanced lung cancer patients. However, the ch
Externí odkaz:
https://doaj.org/article/bd4e64d8943a4db78763ab7d7b778ba1
Autor:
Hiroaki Kanemura, MD, MPH, PhD, Toshihide Yokoyama, MD, Ryu Nakajima, MD, PhD, Atsushi Nakamura, MD, PhD, Hiroaki Kuroda, MD, PhD, Yoshitaka Kitamura, MD, PhD, Hiroyasu Shoda, MD, PhD, Nobuaki Mamesaya, MD, PhD, Yoshihiro Miyata, MD, PhD, Tatsuro Okamoto, MD, PhD, Kyoichi Okishio, MD, PhD, Masahide Oki, MD, PhD, Yuichi Sakairi, MD, PhD, Toyofumi Fengshi Chen-Yoshikawa, MD, PhD, Tadashi Aoki, MD, Tatsuo Ohira, MD, PhD, Isao Matsumoto, MD, PhD, Kiyonobu Ueno, MD, PhD, Takuro Miyazaki, MD, PhD, Haruhisa Matsuguma, MD, PhD, Hideoki Yokouchi, MD, PhD, Tomoyuki Otani, MD, Akihiko Ito, MD, PhD, Kazuko Sakai, PhD, Yasutaka Chiba, PhD, Kazuto Nishio, MD, PhD, Nobuyuki Yamamoto, MD, PhD, Isamu Okamoto, MD, PhD, Kazuhiko Nakagawa, MD, PhD, Masayuki Takeda, MD, PhD
Publikováno v:
JTO Clinical and Research Reports, Vol 5, Iss 4, Pp 100658- (2024)
Introduction: Immune checkpoint inhibitors have recently been approved for the treatment of early-stage NSCLC in the perioperative setting on the basis of phase 3 trials. However, the characteristics of such patients who are susceptible to recurrence
Externí odkaz:
https://doaj.org/article/6165423210284cf69a0cf2aac07b491b
Autor:
Junko Tanizaki, MD, PhD, Hiroaki Kuroda, MD, PhD, Toshihide Yokoyama, MD, Makoto Takahama, MD, PhD, Hiroyasu Shoda, MD, PhD, Atsushi Nakamura, MD, PhD, Yoshitaka Kitamura, MD, PhD, Nobuaki Mamesaya, MD, PhD, Yoshihisa Kadota, MD, PhD, Kenji Sawa, MD, PhD, Kyoichi Okishio, MD, PhD, Morihito Okada, MD, PhD, Chihiro Suminaka, MS, Kenta Noda, PhD, Kazuko Sakai, PhD, Yasutaka Chiba, PhD, Kazuto Nishio, MD, PhD, Kenji Chamoto, PhD, Tasuku Honjo, MD, PhD, Nobuyuki Yamamoto, MD, PhD, Kazuhiko Nakagawa, MD, PhD, Hidetoshi Hayashi, MD, PhD
Publikováno v:
JTO Clinical and Research Reports, Vol 4, Iss 12, Pp 100590- (2023)
Introduction: Perioperative treatment in NSCLC has gained marked attention with the introduction of immune checkpoint inhibitors. Such a paradigm shift has given us additional opportunities to evaluate potential biomarkers in patients with these cura
Externí odkaz:
https://doaj.org/article/3f386ee3f72d427a96a00d99cb19bacc
Autor:
Yuya Nobori, MD, Masaki Anraku, MD, Yoshikane Yamauchi, MD, Mingyon Mun, MD, Ichiro Yoshino, MD, Jun Nakajima, MD, PhD, Norihiko Ikeda, MD, Haruhisa Matsuguma, MD, Takekazu Iwata, MD, Yasushi Shintani, MD, Mitsuo Nakayama, MD, Takahiko Oyama, MD, Masayuki Chida, MD, Hiroaki Kuroda, MD, Hiroshi Hashimoto, MD, Yoko Azuma, MD, Kazuhito Funai, MD, Makoto Endoh, MD, Yukari Uemura, PhD, Masafumi Kawamura, MD
Publikováno v:
JTCVS Open, Vol 13, Iss , Pp 411-422 (2023)
Objective: There is little evidence of the outcome of pulmonary metastasectomy for uterine tumors when comparing different histologies. This study aimed to delineate the primary histology that leads to more favorable outcomes after pulmonary metastas
Externí odkaz:
https://doaj.org/article/720bde3fe8d6475a9e89d880fc1aeeeb
Autor:
Hiroyuki Kishi, Hirokazu Matsushita, Hiroshi Hamana, Yuki Tanaka, Yusuke Takahashi, Rui Yamaguchi, Hisashi Iwata, Fumiaki Watanabe, Trevor Clancy, Daisuke Muraoka, Shuichi Shinohara, Hiroyasu Komuro, Takuya Matsui, Yusuke Sugita, Ayako Demachi-Okamura, Katsuhiro Masago, Reina Nishida, Yoshiki Shigematsu, Katsutoshi Adachi, Hiroaki Kuroda, Yasunori Fukushima, Chieko Takashima, Takashi Ohki, Takashi Fukuyama, Daiki Miura, Kousuke Onoue, Kazuhide Onoguchi, Yoshiko Yamashita, Richard Stratford, Kiyoshi Doi
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 8 (2023)
Background CD8+tumor infiltrating lymphocytes (TILs) are often observed in non-small cell lung cancers (NSCLC). However, the characteristics of CD8+ TILs, especially T-cell populations specific for tumor antigens, remain poorly understood.Methods Hig
Externí odkaz:
https://doaj.org/article/aa0364e659cf47c3b066373e07d1c880
Autor:
Takeo Nakada, Yusuke Takahashi, Noriaki Sakakura, Hiroshi Iwata, Takashi Ohtsuka, Hiroaki Kuroda
Publikováno v:
Current Oncology, Vol 28, Iss 5, Pp 3846-3856 (2021)
In this study, we analyzed prognostic radiological tools and surgical outcomes for radiologically pure solid adenocarcinomas (AD) and squamous cell carcinoma (SQ) in clinical stage IA. We retrospectively investigated 130 patients who underwent surgic
Externí odkaz:
https://doaj.org/article/7762b3797abe4fd6a0cadca000ad2458
Autor:
Takaaki Hasegawa, Hiroaki Kuroda, Noriaki Sakakura, Yozo Sato, Shohei Chatani, Shinichi Murata, Hidekazu Yamaura, Takeo Nakada, Yuko Oya, Yoshitaka Inaba
Publikováno v:
Thoracic Cancer, Vol 12, Iss 14, Pp 2085-2092 (2021)
Abstract Background This study was performed to evaluate the clinical outcomes of hybrid treatment involving surgical resection and percutaneous radiofrequency ablation for patients with multiple lung metastases. Methods Seventeen patients (6 men, 11
Externí odkaz:
https://doaj.org/article/02b0d4ed522d4f47aa51eef45f098833
Autor:
Katsutoshi Adachi, Hiroaki Kuroda, Masayuki Tanahashi, Motoshi Takao, Yasuhisa Ohde, Kohei Yokoi, Tomohito Tarukawa
Publikováno v:
Thoracic Cancer, Vol 12, Iss 11, Pp 1716-1720 (2021)
Abstract Background Premeditated induction chemotherapy followed by surgical resection is accepted as safe and effective. Studies on salvage surgery in patients with incompletely cured lung cancer are lacking. This study aimed to demonstrate the safe
Externí odkaz:
https://doaj.org/article/06c88629968446ea9e0c015dabf6ca08
Autor:
Hiroaki Kuroda, Shozo Sakata, Yusuke Takahashi, Takeo Nakada, Yuko Oya, Yusuke Sugita, Noriaki Sakakura, Hiroakazu Matushita, Yukinori Sakao
Publikováno v:
Thoracic Cancer, Vol 12, Iss 7, Pp 1033-1040 (2021)
Abstract Background The aim of this study was to evaluate regional postoperative preserved pulmonary function (PPPF) and three‐dimensional (3D) volumetric changes according to the number of resected subsegments and investigate the factors that most
Externí odkaz:
https://doaj.org/article/c6b1742a4faa4d60ba7ce36261bde0bb