Zobrazeno 1 - 10
of 107
pro vyhledávání: '"Hiroaki Hisa"'
Publikováno v:
Journal of Pharmacological Sciences, Vol 125, Iss 4, Pp 415-421 (2014)
Abstract.: Renal ischemia produces renal sympathoexcitation that is responsible for the development of ischemic acute kidney injury. The present study examined changes in the sympathetic nerve function in mice. Ischemic acute kidney injury was induce
Externí odkaz:
https://doaj.org/article/96c94bae72044e7f81095b255b4ac417
Publikováno v:
Journal of Pharmacological Sciences, Vol 119, Iss 1, Pp 102-106 (2012)
Clinical and experimental observations indicated that 3-hydroxy-3-methylglutaryl CoA reductase inhibitor statins have pleiotropic effects. The present study determined the antinociceptive property of centrally administered simvastatin on the formalin
Externí odkaz:
https://doaj.org/article/d7167e25c6e244c4a4ae5a11c0099788
Autor:
Tasuku Kanai, Masachika Kuwabara, Naoko Tanaka-Totoribe, Eisaku Nakamura, Yasuko Matsuo, Shuji Gamoh, Akito Suzuki, Yujiro Asada, Hiroaki Hisa, Ryuichi Yamamoto
Publikováno v:
Journal of Pharmacological Sciences, Vol 118, Iss 2, Pp 178-185 (2012)
The aim of this study was to investigate the relaxant effect of insulin on the 5-hydroxytryptamine (5-HT)-induced constriction of the human endothelium-denuded saphenous vein (SV) and its signal transduction pathway. During the 5-HT-induced sustained
Externí odkaz:
https://doaj.org/article/a9c200d02b4e4e24925a7308fabc3ad5
Autor:
Masami Hashimoto, Yoko Takada, Yusuke Takeuchi, Jiro Kasahara, Hiroaki Hisa, Yasufumi Shirasaki, Kohji Fukunaga
Publikováno v:
Journal of Pharmacological Sciences, Vol 98, Iss 2, Pp 142-150 (2005)
We here assessed the effects of 3-[2-[4-(3-chloro-2-methylphenyl)-1-piperazinyl] ethyl]-5,6-dimethoxy-1-(4-imidazolylmethyl)-1H-indazole dihydrochloride 3.5 hydrate (DY-9760e), a novel calmodulin antagonist, on infarct size in the rat heart subjected
Externí odkaz:
https://doaj.org/article/b616cdb2e7d84deb99c0d199a1d4abac
Publikováno v:
Journal of Pharmacological Sciences, Vol 125, Iss 4, Pp 415-421 (2014)
Renal ischemia produces renal sympathoexcitation that is responsible for the development of ischemic acute kidney injury. The present study examined changes in the sympathetic nerve function in mice. Ischemic acute kidney injury was induced by occlus
Autor:
Eisaku Nakamura, Atsuko Yokota, Ryuichi Yamamoto, Shuji Gamoh, Kunihide Nakamura, Tatsuo Shiba, Naoko Tanaka-Totoribe, Masachika Kuwabara, Takahiro Hayase, Hiroaki Hisa
Publikováno v:
Proceedings for Annual Meeting of The Japanese Pharmacological Society. :PO2-3
Autor:
Junpei Mutoh, Junzo Kamei, Masahiro Ohsawa, Hideki Ono, Megumi Asato, Shohei Yamamoto, Hiroaki Hisa
Publikováno v:
European Journal of Pharmacology. 682:56-61
Carnosine is a biologically active dipeptide that is found in fish and chicken muscle. Recent studies have revealed that carnosine has neuroprotective activity in zinc-induced neural cell apoptosis and ischemic stroke. In the present study, we examin
Autor:
Masachika Kuwabara, Naoko Tanaka-Totoribe, Eisaku Nakamura, Ryuichi Yamamoto, Yujiro Asada, Tasuku Kanai, Shuji Gamoh, Yasuko Matsuo, Hiroaki Hisa, Akito Suzuki
Publikováno v:
Journal of Pharmacological Sciences, Vol 118, Iss 2, Pp 178-185 (2012)
The aim of this study was to investigate the relaxant effect of insulin on the 5-hydroxytryptamine (5-HT)-induced constriction of the human endothelium-denuded saphenous vein (SV) and its signal transduction pathway. During the 5-HT-induced sustained
Publikováno v:
Journal of Pharmacological Sciences, Vol 119, Iss 1, Pp 102-106 (2012)
Clinical and experimental observations indicated that 3-hydroxy-3-methylglutaryl CoA reductase inhibitor statins have pleiotropic effects. The present study determined the antinociceptive property of centrally administered simvastatin on the formalin
Publikováno v:
Neuroscience. 333
Small molecular G-protein plays a key role in several diseases. This study was designed to reveal the role of RhoA signaling in the pathophysiology of neuropathic pain in mice. Partial sciatic nerve injury caused thermal hyperalgesia, mechanical allo