Zobrazeno 1 - 10
of 272
pro vyhledávání: '"Hiroaki, Tateno"'
Autor:
Hao Nie, Pratima Saini, Taito Miyamoto, Liping Liao, Rafal J. Zielinski, Heng Liu, Wei Zhou, Chen Wang, Brennah Murphy, Martina Towers, Tyler Yang, Yuan Qi, Toshitha Kannan, Andrew Kossenkov, Hiroaki Tateno, Daniel T. Claiborne, Nan Zhang, Mohamed Abdel-Mohsen, Rugang Zhang
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Aberrant glycosylation is a crucial strategy employed by cancer cells to evade cellular immunity. However, it’s unclear whether homologous recombination (HR) status-dependent glycosylation can be therapeutically explored. Here, we show tha
Externí odkaz:
https://doaj.org/article/f6c6df012ec140a7a4fd2deb6a11201f
Autor:
Tianwei Huang, Yuya Sato, Akiko Kuramochi, Yoshio Ohba, Masayuki Sano, Makoto Miyagishi, Hiroaki Tateno, Renu Wadhwa, Kazunori Kawasaki, Takeyuki Uchida, Kristina N. Ekdahl, Bo Nilsson, Ung-il Chung, Yuji Teramura
Publikováno v:
Regenerative Therapy, Vol 22, Iss , Pp 90-98 (2023)
Exosomes (diameter 30–200 nm) are a subtype of extracellular vesicles secreted by cells containing DNA, microRNA (miRNA), and proteins. Exosomes are expected to be valuable as a means of delivering drugs or functional miRNAs in treatment of disease
Externí odkaz:
https://doaj.org/article/848925f978da4a4395047b7007ba6239
Autor:
Masamichi Nagae, Tetsuya Hirata, Hiroaki Tateno, Sushil K. Mishra, Noriyoshi Manabe, Naoko Osada, Yuko Tokoro, Yoshiki Yamaguchi, Robert J. Doerksen, Toshiyuki Shimizu, Yasuhiko Kizuka
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-11 (2022)
X-ray crystallography together with NMR and computer modelling shed light on the structure and catalytic mechanism of GnTIVa, a key enzyme involved in GlcNAc branch synthesis, that bears an unusual C-terminal lectin domain that regulates its catalyti
Externí odkaz:
https://doaj.org/article/4635a14557324c489214f7372e4e5c23
Publikováno v:
BMC Gastroenterology, Vol 22, Iss 1, Pp 1-10 (2022)
Abstract Background Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest gastrointestinal cancers with a 5-year survival rate of less than 10%. Biomarkers for early PDAC detection are useful in treating patients with PDAC. Extracellular ve
Externí odkaz:
https://doaj.org/article/beecb7c34e294c41935cfdb38a7f0c4e
Autor:
Ea Kristine Clarisse Tulin, Chiaki Nakazawa, Tomomi Nakamura, Shion Saito, Naoki Ohzono, Keiko Hiemori, Shin-ichi Nakakita, Hiroaki Tateno, Takashi Tonozuka, Atsushi Nishikawa
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Lectins are proteins with the ability to recognize and bind to specific glycan structures. These molecules play important roles in many biological systems and are actively being studied because of their ability to detect glycan biomarkers fo
Externí odkaz:
https://doaj.org/article/cc0966aae15445da915caa89bf072130
Publikováno v:
FEBS Open Bio, Vol 11, Iss 3, Pp 741-752 (2021)
Alzheimer's disease (AD) is the most common form of dementia, characterized by the accumulation of β‐amyloid plaques and the formation of neurofibrillary tangles. Extracellular vesicles (EVs) are small vesicles surrounded by a lipid bilayer membra
Externí odkaz:
https://doaj.org/article/5e37a2b6f8af47e688d8e7f61f0307c7
Autor:
Lalhaba Oinam, Hiroaki Tateno
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Glycans are essential building blocks of life that are located at the outermost surface of all cells from mammals to bacteria and even viruses. Cell surface glycans mediate multicellular communication in diverse biological processes and are useful as
Externí odkaz:
https://doaj.org/article/02b548f00a7b477b9c7c409956677a71
Publikováno v:
STAR Protocols, Vol 3, Iss 1, Pp 101179- (2022)
Summary: Glycans are structurally diverse molecules found on the surface of living cells. The protocol details a system developed for combined analysis of glycan and RNA in single cells (scGR-seq) using human induced pluripotent stem cells (hiPSCs) a
Externí odkaz:
https://doaj.org/article/bb6f45fd6cc14df794a8d999d23a042a
Autor:
Naohiro Seo, Junko Nakamura, Tsuguhiro Kaneda, Hiroaki Tateno, Asako Shimoda, Takanori Ichiki, Koichi Furukawa, Jun Hirabayashi, Kazunari Akiyoshi, Hiroshi Shiku
Publikováno v:
Journal of Extracellular Vesicles, Vol 11, Iss 3, Pp n/a-n/a (2022)
Abstract The development of a new large‐scale purification protocol is required for research on the reliable bioactivity and drug discovery of extracellular vesicles (EVs). To address this issue, herein, we propose an effective method for preparing
Externí odkaz:
https://doaj.org/article/ec048ebd4cd04199bbc9a4fcae2aff61
Autor:
Yoshikazu Haramoto, Yasuko Onuma, Shuuji Mawaribuchi, Yoshiro Nakajima, Yasuhiko Aiki, Kumiko Higuchi, Madoka Shimizu, Hiroaki Tateno, Jun Hirabayashi, Yuzuru Ito
Publikováno v:
Regenerative Therapy, Vol 14, Iss , Pp 306-314 (2020)
Introduction: Tumourigenesis attributed to residual undifferentiated cells in a graft is considered to be a significant issue in cell therapy using human pluripotent stem cells. To ensure the safety of regenerative medicine derived from pluripotent s
Externí odkaz:
https://doaj.org/article/f96df89f1fe7470286eb8cce3bbb1c39