Zobrazeno 1 - 10
of 83
pro vyhledávání: '"Hiroaki, Moriyama"'
Autor:
Naoto Shiba, Masafumi Inoue, Masafumi Gotoh, Takahiro Okawa, Hiroaki Moriyama, Yasuhiro Mitsui, Hiroki Ohzono, Hidehiro Nakamura, Suguru Tanaka
Publikováno v:
The Kurume medical journal. 66(4)
Introduction Current advances in arthroscopic surgery have led to good outcomes for arthroscopic Bankart repair (ABR) for recurrent anterior shoulder dislocation. However, recent studies have reported recurrence rates of 4%-19% after ABR. In our surv
Autor:
Masafumi Gotoh, Naoto Shiba, Koji Tanaka, Hiroaki Moriyama, Hidehiro Nakamura, Hiroki Ozono, Takahiro Okawa, Yashuhiro Mitsui
Publikováno v:
Orthopaedic Journal of Sports Medicine
Background:Previous studies have shown good clinical outcomes in patients with irreparable large or massive rotator cuff tears treated using arthroscopic partial repair (APR); however, few studies have evaluated both functional and structural outcome
Autor:
Hiroaki Moriyama, Masafumi Gotoh, Koji Tanaka, Yashuhiro Mitsui, Hidehiro Nakamura, Hiroki Ozono, Takahiro Okawa, Naoto Shiba
Publikováno v:
Orthopaedic Journal of Sports Medicine; Mar2021, Vol. 9 Issue 3, p1-8, 8p
Autor:
Iichiro Shimomura, Tohru Funahashi, Akihisa Imagawa, Kohei Okita, Tetsuhiro Kitamura, Toshiaki Hanafusa, Masaya Yamaoka, Masao Nagata, Michio Otsuki, Hiroaki Moriyama, Yukako Sakaguchi, Yoshihito Shima, Fumitaka Haseda, Hiromi Iwahashi
Publikováno v:
Diabetology International. 3:50-53
Several lines of evidence have suggested that pancreatic β-cell destruction is caused by inflammatory cellular responses mediated by T lymphocytes in individuals with type 1A diabetes. B lymphocytes, which play an important role in the production of
Acceleration of autoimmune diabetes in Rheb-congenic NOD mice with β-cell-specific mTORC1 activation
Autor:
Mami Shimizu, Akira Nakamura, Hirotomo Sasaki, Masao Nagata, Kenta Hara, Hisafumi Yasuda, Hiroaki Moriyama, Koichi Yokono, Takashi Arai
Publikováno v:
Biochemical and Biophysical Research Communications. 408:306-311
The protein Ras homolog enriched in brain (Rheb) is a Ras-like small GTPase that activates the mechanistic target of rapamycin complex 1 (mTORC1), which promotes cell growth. We previously generated transgenic C57BL/6 mice overexpressing Rheb in β-c
Autor:
Hiroaki Moriyama, Takashi Sakurai, Taichi Akisaki, Miyako Taniguchi, Saeko Kushida, Masao Nagata, Katsuya Urakami, Kenta Hara, Koichi Yokono, Hisafumi Yasuda
Publikováno v:
Geriatrics & Gerontology International. 11:114-118
It is often difficult to diagnose disease in elderly patients, in particular those with dementia, who do not present with typical symptoms. This report describes our experience of an elderly patient (an 83-year-old woman) who presented with a chief c
Autor:
Yuichi Hori, Yonson Ku, Masashi Yamamoto, Yoshikazu Kuroda, Masao Nagata, Hiroshi Hasegawa, Daisuke Kuroda, Kimihiro Yamashita, Takashi Kamigaki, Hiroaki Moriyama
Publikováno v:
Oncology Reports. 22(2):337-343
Regulatory T cells (Tregs) play an important role in immunological self-tolerance and protect the host from autoimmune disease. However, in cancer immunity, Tregs might block anti-tumor immune responses. Therefore, the depletion of Tregs using a spec
Autor:
Hiroaki Moriyama, Suirin Hamada, Masao Nagata, Koichi Yokono, Kenta Hara, Hisafumi Yasuda, Takeshi Hamada, Rika Nakayama
Publikováno v:
Diabetes
OBJECTIVE Components of insulin/IGF-1 receptor–mediated signaling pathways in pancreatic β-cells have been implicated in the development of diabetes, in part through the regulation of β-cell mass in vivo. Studies in vitro have shown that the prot
Autor:
Yasuyo Okumachi, Hirofumi Hamada, Minoru Kishi, Hiroaki Moriyama, Katsumi Yamada, Muneaki Sakata, Koichi Yokono, Masao Nagata, Reiko Kotani, Hisafumi Yasuda, Kenta Hara, Takashi Arai, Midori Kurohara
Publikováno v:
Diabetes Research and Clinical Practice. 80:352-359
Pancreatic islet transplantation has the potential to maintain normoglycemia in patients with established type 1 diabetes, thereby obviating the need for frequent insulin injections. Our previous study showed that recombinant IL-12p40-producing islet
Autor:
Yasuyo Okumachi, Katsumi Yamada, Takashi Arai, Koich Yokono, Hiroaki Moriyama, Kenta Hara, Hisafumi Yasuda, Masao Nagata, Reiko Kotani
Publikováno v:
Diabetes Research and Clinical Practice. 77:S155-S160
Rodents have two functional preproinsulin genes named insulin 1 and insulin 2 on different chromosome and have two amino acid differences in insulin B chain. We have established insulin 1 or insulin 2 knockout (KO) non-obese diabetic (NOD) colonies i