Zobrazeno 1 - 10
of 96
pro vyhledávání: '"Hiroaki, Hiraga"'
Autor:
Toshiyuki Nishimoto, Hirokazu Shimizu, Masatake Matsuoka, Daisuke Takahashi, Tomohiro Shimizu, Norimasa Iwasaki, Ken Kuwahara, Tamotsu Soma, Hiroaki Hiraga, Akira Iwata
Publikováno v:
BMC Musculoskeletal Disorders, Vol 25, Iss 1, Pp 1-7 (2024)
Abstract Background Prophylactic intervention for impending pathological fractures (IF) is associated with improved survival in patients with long-bone metastasis. However, information regarding whether the tumor burden and/or physical status are ass
Externí odkaz:
https://doaj.org/article/f369fb5a6a47488fa44828ca73a99d9c
Autor:
Makoto Endo, Tomoko Kataoka, Toshifumi Fujiwara, Satoshi Tsukushi, Masanobu Takahashi, Eisuke Kobayashi, Yoko Yamada, Takaaki Tanaka, Yutaka Nezu, Hiroaki Hiraga, Junji Wasa, Akihito Nagano, Kenji Nakano, Robert Nakayama, Tetsuya Hamada, Masanori Kawano, Tomoaki Torigoe, Akio Sakamoto, Kunihiro Asanuma, Takeshi Morii, Ryunosuke Machida, Yuta Sekino, Haruhiko Fukuda, Yoshinao Oda, Toshifumi Ozaki, Kazuhiro Tanaka
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-8 (2023)
Abstract Background Soft tissue sarcomas (STS) are a rare type of malignancy comprising a variety of histological diagnoses. Chemotherapy constitutes the standard treatment for advanced STS. Doxorubicin-based regimens, which include the administratio
Externí odkaz:
https://doaj.org/article/fbc2c36541c844a2894c17228bd7e226
Autor:
Yutaka Fukaya, Toshimi Kimura, Yukihiro Hamada, Kenichi Yoshimura, Hiroaki Hiraga, Yuki Yuza, Atsushi Ogawa, Junichi Hara, Katsuyoshi Koh, Atsushi Kikuta, Yuhki Koga, Hiroshi Kawamoto
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
IntroductionGlucarpidase (CPG2) reduces the lethal toxicity of methotrexate (MTX) by rapid degradation.MethodsIn this study, a CPG2 population pharmacokinetics (popPK) analysis in healthy volunteers (phase 1 study) and a popPK-pharmacodynamics (popPK
Externí odkaz:
https://doaj.org/article/292f626a73b4408999f2f71b86f39e93
Autor:
Masanori Okamoto, Masatake Matsuoka, Tamotsu Soma, Ryuta Arai, Hidenori Kato, Toru Harabayashi, Hirohumi Adachi, Toshiki Shinohara, Tamotsu Sagawa, Noriaki Nishiyama, Toshikazu Nambu, Wataru Sakai, Hiroaki Suzuki, Hiroyuki Kato, Hiroaki Hiraga
Publikováno v:
Cancer Medicine, Vol 9, Iss 17, Pp 6159-6165 (2020)
Abstract Background Hepatic metastasis of soft tissue sarcoma is rare compared to lung metastasis, and the literature is scarce. We examined the risk of hepatic metastasis according to the site of occurrence and histological type. Methods From a Hosp
Externí odkaz:
https://doaj.org/article/34d332fb7c6c48cb99267ca5101c3e8e
Autor:
Makoto Endo, Shunji Takahashi, Nobuhito Araki, Hideshi Sugiura, Takafumi Ueda, Tsukasa Yonemoto, Mitsuru Takahashi, Hideo Morioka, Hiroaki Hiraga, Toru Hiruma, Toshiyuki Kunisada, Akihiko Matsumine, Kazato Goda, Akira Kawai
Publikováno v:
Cancer Medicine, Vol 9, Iss 11, Pp 3656-3667 (2020)
Abstract The time course of the response to each drug is important to avoid inappropriate termination of treatment by misjudging tumor progression; however, little is known about soft tissue sarcoma (STS) regarding this matter. This study aimed to pe
Externí odkaz:
https://doaj.org/article/72f22d66938e4509814e74c406f73671
Autor:
Makoto Hirata, Naofumi Asano, Kotoe Katayama, Akihiko Yoshida, Yusuke Tsuda, Masaya Sekimizu, Sachiyo Mitani, Eisuke Kobayashi, Motokiyo Komiyama, Hiroyuki Fujimoto, Takahiro Goto, Yukihide Iwamoto, Norifumi Naka, Shintaro Iwata, Yoshihiro Nishida, Toru Hiruma, Hiroaki Hiraga, Hirotaka Kawano, Toru Motoi, Yoshinao Oda, Daisuke Matsubara, Masashi Fujita, Tatsuhiro Shibata, Hidewaki Nakagawa, Robert Nakayama, Tadashi Kondo, Seiya Imoto, Satoru Miyano, Akira Kawai, Rui Yamaguchi, Hitoshi Ichikawa, Koichi Matsuda
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Understanding the genomic features of dedifferentiated liposarcoma (DDLPS) is likely to uncover new options for management. Here, the authors reveal three prognostic groups, and highlight molecular markers associated with malignant transformation.
Externí odkaz:
https://doaj.org/article/3e31fbc9656042eb9965085ae0110e72
Autor:
Kazuhiro Tanaka, Junki Mizusawa, Norifumi Naka, Akira Kawai, Hirohisa Katagiri, Toru Hiruma, Yoshihiro Matsumoto, Hiroyuki Tsuchiya, Robert Nakayama, Hiroshi Hatano, Makoto Emori, Munenori Watanuki, Yukihiro Yoshida, Takeshi Okamoto, Satoshi Abe, Kunihiro Asanuma, Ryohei Yokoyama, Hiroaki Hiraga, Tsukasa Yonemoto, Takeshi Morii, Keisuke Ae, Akihito Nagano, Hideki Yoshikawa, Haruhiko Fukuda, Toshifumi Ozaki, Yukihide Iwamoto
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-7 (2019)
Abstract Background Soft-tissue sarcomas (STS) are rare malignant tumors those are resistant to chemotherapy. We have previously reported the 3-year follow-up result on the efficacy of perioperative chemotherapy with doxorubicin (DXR) and ifosfamide
Externí odkaz:
https://doaj.org/article/d31afd75fc504fdeb97c20cf9778e057
Autor:
Kazuhiro Tanaka, Gakuto Ogawa, Junki Mizusawa, Norifumi Naka, Akira Kawai, Mitsuru Takahashi, Toru Hiruma, Yoshihiro Matsumoto, Hiroyuki Tsuchiya, Robert Nakayama, Hiroshi Hatano, Makoto Emori, Masami Hosaka, Yukihiro Yoshida, Junya Toguchida, Satoshi Abe, Kunihiro Asanuma, Ryohei Yokoyama, Hiroaki Hiraga, Tsukasa Yonemoto, Takeshi Morii, Seiichi Matsumoto, Akihito Nagano, Hideki Yoshikawa, Haruhiko Fukuda, Toshifumi Ozaki, Yukihide Iwamoto
Publikováno v:
World Journal of Surgical Oncology, Vol 16, Iss 1, Pp 1-8 (2018)
Abstract Background Soft tissue sarcomas (STS) are rare malignant tumors. The efficacy of preoperative chemotherapy for STS is evaluated using various tumor size-based radiological response criteria. However, it is still unclear which set of criteria
Externí odkaz:
https://doaj.org/article/860c8f327551477b9012d7f0abec1987
Autor:
Hiroshi Urakawa, Tsukasa Yonemoto, Seiichi Matsumoto, Tatsuya Takagi, Kunihiro Asanuma, Munenori Watanuki, Akira Takemoto, Norifumi Naka, Yoshihiro Matsumoto, Akira Kawai, Toshiyuki Kunisada, Tadahiko Kubo, Makoto Emori, Hiroaki Hiraga, Hiroshi Hatano, Satoshi Tsukushi, Yoshihiro Nishida, Toshihiro Akisue, Takeshi Morii, Mitsuru Takahashi, Akihito Nagano, Hideki Yoshikawa, Kenji Sato, Masanori Kawano, Koji Hiraoka, Kazuhiro Tanaka, Yukihide Iwamoto, Toshifumi Ozaki
Publikováno v:
World Journal of Surgical Oncology, Vol 16, Iss 1, Pp 1-8 (2018)
Abstract Background Giant cell tumor of bone (GCTB) is an intermediate tumor known to be locally aggressive, but rarely metastasizing. To plan a prospective study of GCTB, we performed a questionnaire survey for institutions participating in the Bone
Externí odkaz:
https://doaj.org/article/06fc3859d18c4c1fbaf9c9d009b5284c
Autor:
Kazuhiro Tanaka, Ryunosuke Machida, Akira Kawai, Robert Nakayama, Satoshi Tsukushi, Kunihiro Asanuma, Yoshihiro Matsumoto, Hiroaki Hiraga, Koji Hiraoka, Munenori Watanuki, Tsukasa Yonemoto, Satoshi Abe, Hirohisa Katagiri, Yoshihiro Nishida, Akihito Nagano, Yoshiyuki Suehara, Hiroyuki Kawashima, Masanori Kawano, Takeshi Morii, Hiroshi Hatano, Junya Toguchida, Tomotake Okuma, Masanobu Takeyama, Satoshi Takenaka, Toshihiro Akisue, Taisuke Furuta, Makoto Emori, Toru Hiruma, Hidetatsu Outani, Tetsuji Yamamoto, Tomoko Kataoka, Haruhiko Fukuda, Toshifumi Ozaki, Yukihide Iwamoto
Publikováno v:
British Journal of Cancer. 127:1487-1496
Background This randomised phase II/III trial aimed to determine whether perioperative chemotherapy with gemcitabine plus docetaxel (GD) is non-inferior to the standard Adriamycin plus ifosfamide (AI) in terms of overall survival (OS) in patients wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::809e411b1df801edfeb02c59b42a1154
https://doi.org/10.1038/s41416-022-01912-5
https://doi.org/10.1038/s41416-022-01912-5