Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Hiren Karathia"'
Autor:
Manoj Kumar Kashyap, Hiren Karathia, Deepak Kumar, Roberto Vera Alvarez, Jose Vicente Forero-Forero, Eider Moreno, Juliana Velez Lujan, Carlos Ivan Amaya-Chanaga, Newton Medeiros Vidal, Zhe Yu, Emanuela M. Ghia, Paula A. Lengerke-Diaz, Daniel Achinko, Michael Y. Choi, Laura Z. Rassenti, Leonardo Mariño-Ramírez, Stephen M. Mount, Sridhar Hannenhalli, Thomas J. Kipps, Januario E. Castro
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 35, Iss 2, Pp 102202- (2024)
Splicing factor 3b subunit 1 (SF3B1) is the largest subunit and core component of the spliceosome. Inhibition of SF3B1 was associated with an increase in broad intron retention (IR) on most transcripts, suggesting that IR can be used as a marker of s
Externí odkaz:
https://doaj.org/article/adf59c81f6f94126a63b606708311ab5
Autor:
Maureen M. Leonard, Hiren Karathia, Meritxell Pujolassos, Jacopo Troisi, Francesco Valitutti, Poorani Subramanian, Stephanie Camhi, Victoria Kenyon, Angelo Colucci, Gloria Serena, Salvatore Cucchiara, Monica Montuori, Basilio Malamisura, Ruggiero Francavilla, Luca Elli, Brian Fanelli, Rita Colwell, Nur Hasan, Ali R. Zomorrodi, Alessio Fasano, the CD-GEMM Team
Publikováno v:
Microbiome, Vol 8, Iss 1, Pp 1-15 (2020)
Abstract Background Celiac disease (CD) is an autoimmune digestive disorder that occurs in genetically susceptible individuals in response to ingesting gluten, a protein found in wheat, rye, and barley. Research shows that genetic predisposition and
Externí odkaz:
https://doaj.org/article/ce798c17b1504d999ed1882d345fbda6
Autor:
Noam Auslander, Daniel M Ramos, Ivette Zelaya, Hiren Karathia, Thomas O. Crawford, Alejandro A Schäffer, Charlotte J Sumner, Eytan Ruppin
Publikováno v:
Molecular Systems Biology, Vol 16, Iss 12, Pp n/a-n/a (2020)
Abstract Modifier genes are believed to account for the clinical variability observed in many Mendelian disorders, but their identification remains challenging due to the limited availability of genomics data from large patient cohorts. Here, we pres
Externí odkaz:
https://doaj.org/article/3de22a2ac37c4d438a901282d752a3e5
Autor:
Abasiofiok Ibekwe, Lisa Durso, Thomas F. Ducey, Adelumola Oladeinde, Charlene R. Jackson, Jonathan G. Frye, Robert Dungan, Tom Moorman, John P. Brooks, Amarachukwu Obayiuwana, Hiren Karathia, Brian Fanelli, Nur Hasan
Publikováno v:
Microorganisms, Vol 9, Iss 5, p 1057 (2021)
Antimicrobial resistance associated with the spread of plasmid-encoded extended-spectrum β-lactamase (ESBL) genes conferring resistance to third generation cephalosporins is increasing worldwide. However, data on the population of ESBL producing E.
Externí odkaz:
https://doaj.org/article/9ef2d19698e4454ea34f0c8549ec0eef
Publikováno v:
PeerJ, Vol 2, p e276 (2014)
One way to initiate the reconstruction of molecular circuits is by using automated text-mining techniques. Developing more efficient methods for such reconstruction is a topic of active research, and those methods are typically included by bioinforma
Externí odkaz:
https://doaj.org/article/9cc5b5a304fd404eb4ad9c497c410a4a
Autor:
Jordi Vilaplana, Francesc Solsona, Ivan Teixido, Anabel Usié, Hiren Karathia, Rui Alves, Jordi Mateo
Publikováno v:
The Scientific World Journal, Vol 2014 (2014)
Our group developed two biological applications, Biblio-MetReS and Homol-MetReS, accessing the same database of organisms with annotated genes. Biblio-MetReS is a data-mining application that facilitates the reconstruction of molecular networks based
Externí odkaz:
https://doaj.org/article/7c2861b4cb2a4eb5b02f0b78c9417222
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e31095 (2012)
Signal transduction systems mediate the response and adaptation of organisms to environmental changes. In prokaryotes, this signal transduction is often done through Two Component Systems (TCS). These TCS are phosphotransfer protein cascades, and in
Externí odkaz:
https://doaj.org/article/32b8771cf6b74974b7030a71b1e97e5f
Publikováno v:
PLoS ONE, Vol 6, Iss 2, p e16015 (2011)
BACKGROUND: Model organisms are used for research because they provide a framework on which to develop and optimize methods that facilitate and standardize analysis. Such organisms should be representative of the living beings for which they are to s
Externí odkaz:
https://doaj.org/article/0eda0a358bd54d1c8eb685cb72ecd783
Autor:
Manoj Kumar Kashyap, Hiren Karathia, Deepak Kumar, Roberto Vera Alvarez, Paula A Lengerke-Diaz, Jose Vicente Forero-Forero, Eider Moreno, Juliana Velez Lujan, Carlos Ivan Amaya-Chanaga, Newton Medeiros Vidal, Zhe Yu, Daniel Achinko, Emanuela M. Ghia, Michael Y. Choi, Laura Z. Rassenti, Leonardo Mariño-Ramírez, Stephen M. Mount, Sridhar Hannenhalli, Thomas J. Kipps, Januario E. Castro
BackgroundAlternative splicing (AS) is a fundamental process in eukaryotes contributing to the diversity of mRNA isoforms with variable ratios of intron/exon. SF3B1 is a pivotal protein of the spliceosome machinery. Mutations in the SF3B1 gene have p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e9780fc833c4337eeaff49ae6153d3bf
https://doi.org/10.21203/rs.3.rs-1622375/v1
https://doi.org/10.21203/rs.3.rs-1622375/v1
Autor:
Nur A. Hasan, Hiren Karathia, Abigail A. Weaver, Rita R. Colwell, Joshua D. Shrout, Mark Klaassen
Publikováno v:
J Med Microbiol
Introduction. Prosthetic joint infections (PJIs) are challenging to treat therapeutically because the infectious agents often are resistant to antibiotics and capable of abundant growth in surface-attached biofilms. Though infection rates are low, ca