Zobrazeno 1 - 10
of 122
pro vyhledávání: '"Hiran Perera"'
Publikováno v:
Journal of Urology. 209
Publikováno v:
Journal of Functional Biomaterials, Vol 11, Iss 1, p 15 (2020)
Low neural tissue extracellular matrix (ECM) content has led to the understudy of its effects on neural cells and tissue. Hyaluronic acid (HA) and laminin are major neural ECM components, but direct comparisons of their cellular effects could not be
Externí odkaz:
https://doaj.org/article/2f32cbf376d04f84a50a3955748a6c8f
Publikováno v:
Biomacromolecules. 20:3009-3020
Cellular remodeling of the matrix has recently emerged as a key factor in promoting neural differentiation. Most strategies to manipulate matrix remodeling focus on proteolytically cleavable cross-linkers, leading to changes in tethered biochemical s
Autor:
Hyun Ju, Lim, Zara, Khan, Thomas S, Wilems, Xi, Lu, T Hiran, Perera, Yuki E, Kurosu, Krishna T, Ravivarapu, Matthew C, Mosley, Laura A, Smith Callahan
Publikováno v:
ACS biomaterials scienceengineering. 3(5)
Although preclinical models of spinal cord injury have shown that matrix inclusion in stem cell therapy leads to greater neurological improvements than that including cells alone, there has been insufficient matrix optimization for human cells.
Autor:
Ali Azhdarinia, Hyun Ju Lim, Qilin Cao, Thomas S. Wilems, Sukhen C. Ghosh, T. Hiran Perera, Laura A. Smith Callahan, Yi Yan Zheng
Publikováno v:
Journal of materials chemistry. B. 4(42)
Hyaluronic acid (HA) with one reactive moiety grafted to the backbone is a commonly used matrix in tissue engineering. The addition of a second orthogonal moiety to the backbone allows for greater control in bioactive signal tethering and gelation. I
Publikováno v:
Journal of Experimental Pharmacology
Polyethylene glycol (PEG) is a synthetic biocompatible polymer with many useful properties for developing therapeutics to treat spinal cord injury. Direct application of PEG as a fusogen to the injury site can repair cell membranes, mitigate oxidativ
Autor:
Hyun Ju Lim, Yuki E. Kurosu, Zara Khan, Laura A. Smith Callahan, Thomas S. Wilems, Matthew C. Mosley, T. Hiran Perera, Krishna T. Ravivarapu, Xi Lu
Publikováno v:
ACS Biomaterials Science & Engineering. 3:776-781
Although preclinical models of spinal cord injury have shown that matrix inclusion in stem cell therapy leads to greater neurological improvements than that including cells alone, there has been insufficient matrix optimization for human cells. N-Cad
Publikováno v:
Advanced Biosystems. 4:2000084
Extracellular matrix (ECM) remodeling is emerging as a modulator of neural maturation and axon extension. Most studies have used rodent cells to develop matrices capable of manipulating extracellular matrix remodeling for regenerative applications. H
Publikováno v:
Journal of Functional Biomaterials, Vol 11, Iss 1, p 15 (2020)
Journal of Functional Biomaterials
Volume 11
Issue 1
Journal of Functional Biomaterials
Volume 11
Issue 1
Low neural tissue extracellular matrix (ECM) content has led to the understudy of its effects on neural cells and tissue. Hyaluronic acid (HA) and laminin are major neural ECM components, but direct comparisons of their cellular effects could not be
Autor:
Hyun Ju Lim, Thomas S. Wilems, Xi Lu, T. Hiran Perera, Zara Khan, Laura A. Smith Callahan, Krishna T. Ravivarapu
Publikováno v:
Acta biomaterialia. 71
Balancing enhancement of neurite extension against loss of matrix support in synthetic hydrogels containing proteolytically degradable and bioactive signaling peptides to optimize tissue formation is difficult. Using a systematic approach, polyethyle