Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Hiram Hernández-López"'
Autor:
Cesia M. Aguilar-Morales, América A. Frías-López, Nadia V. Emilio-Velázquez, Alejandro Islas-Jácome, Angelica Judith Granados-López, Jorge Gustavo Araujo-Huitrado, Yamilé López-Hernández, Hiram Hernández-López, Luis Chacón-García, Jesús Adrián López, Carlos J. Cortés-García
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 20, Iss 1, Pp 3077-3084 (2024)
A series of 1,5-disubstituted tetrazole-indole hybrids were synthesized via a high-order multicomponent reaction consisting of an Ugi-azide/Pd/Cu-catalyzed hetero-annulation cascade sequence. This operationally simple one-pot protocol allowed high bo
Externí odkaz:
https://doaj.org/article/005fa626141148e0962b0b132ff09bad
Autor:
L. Angel Veyna-Hurtado, Hiram Hernández-López, Fuensanta Reyes-Escobedo, Mitzzy Medellín-Luna, Salvador García-Cruz, Lorena Troncoso-Vázquez, Irma E. González-Curiel, Marisol Galván-Valencia, Julio E. Castañeda-Delgado, Alberto Rafael Cervantes-Villagrana
Publikováno v:
Medicine in Drug Discovery, Vol 19, Iss , Pp 100160- (2023)
The discovery and implementation of antibiotics led to a better prognosis for infectious diseases. Fluoroquinolones are a family of antibiotics with a broad spectrum of action and antibacterial effectiveness. Because bacterial strains have increased
Externí odkaz:
https://doaj.org/article/c98bb536c194405285b969baf88bf50f
Autor:
Mitzzy Fátima Medellín-Luna, Hiram Hernández-López, Julio Enrique Castañeda-Delgado, Fidel Martinez-Gutierrez, Edgar Lara-Ramírez, Joan Jair Espinoza-Rodríguez, Salvador García-Cruz, Diana Patricia Portales-Pérez, Alberto Rafael Cervantes-Villagrana
Publikováno v:
Molecules, Vol 28, Iss 16, p 6018 (2023)
Structure–activity relationship (SAR) studies allow the evaluation of the relationship between structural chemical changes and biological activity. Fluoroquinolones have chemical characteristics that allow their structure to be modified and new ana
Externí odkaz:
https://doaj.org/article/57282e8a85994177bda9a10178e22f26
Autor:
Hiram Hernández-López, Socorro Leyva-Ramos, Cesar Fernando Azael Gómez-Durán, Alberto Pedraza-Alvarez, Irving Rubén Rodríguez-Gutiérrez, Mario Alberto Leyva-Peralta, Rodrigo Said Razo-Hernández
Publikováno v:
ACS Omega, Vol 5, Iss 23, Pp 14061-14068 (2020)
Externí odkaz:
https://doaj.org/article/9922ce9afd9745b9a9f67293957da96e
Autor:
José Antonio Varela-Silva, Miguel Ernesto Martínez-Leija, Sandra Teresa Orta-García, Ivan Nelinho Pérez-Maldonado, Jesús Adrián López, Hiram Hernández-López, Roberto González-Amaro, Emma S. Calderón-Aranda, Diana Patricia Portales-Pérez, Mariana Salgado-Bustamante
Publikováno v:
Toxics, Vol 11, Iss 1, p 28 (2022)
The exposure to air pollutants causes significant damage to health, and inefficient cooking and heating practices produce high levels of household air pollution, including a wide range of health-damaging pollutants such as fine particles, carbon mono
Externí odkaz:
https://doaj.org/article/6696e9c7b04a4e4f95bde5abecc1a193
Autor:
Hiram Hernández-López, Griselda Sánchez-Miranda, Jorge Gustavo Araujo-Huitrado, Angelica Judith Granados-López, Jesús Adrián López, Socorro Leyva-Ramos, Luis Chacón-García
Publikováno v:
Journal of Chemistry, Vol 2019 (2019)
Quinolones are a family of antimicrobial agents that have been used in antibacterial and anticancer chemotherapy. Fluoroquinolone targets DNA gyrase and topoisomerase IV enzymes affecting several cellular processes, like cell death and proliferation;
Externí odkaz:
https://doaj.org/article/29a9560706f048cdb3c4e278bf82924d
Autor:
Sergio Córdova-Rivas, Jorge Gustavo Araujo-Huitrado, Ernesto Rivera-Avalos, Ismailia L. Escalante-García, Sergio M. Durón-Torres, Yamilé López-Hernández, Hiram Hernández-López, Lluvia López, Denisse de Loera, Jesús Adrián López
Publikováno v:
Molecules, Vol 25, Iss 9, p 2058 (2020)
We previously showed that microwave assisted synthesis is the best method for the synthesis of naphthoquinone amino acid and chloride-naphthoquinone amino acid derivatives by a complete evaluation of reaction conditions such as stoichiometry, bases,
Externí odkaz:
https://doaj.org/article/7ec872459f5541fb9ef2d5160107de7c
Autor:
Elisa Leyva, Johana Aguilar, Silvia Elena Loredo-Carrillo, Agobardo Cárdenas-Chaparro, Antonio Martínez-Richa, Hiram Hernández-López, Jorge Gustavo Araujo-Huitrado, Angélica Judith Granados-López, Yamilé López-Hernández, Jesús Adrián López
Publikováno v:
Current Organic Synthesis. 20
Aims: Aims: Perform the synthesis of novel fluoro phenyl triazoles via click chemistry with or without microwave irradiation and their evaluation as anti-proliferative agents in SiHa cells background: Triazoles are heterocyclic compounds containing a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e5f6bfd571b6dcc72e6eedec9e6d4a8a
https://doi.org/10.2174/1570179420666230420084000
https://doi.org/10.2174/1570179420666230420084000
Autor:
Jaime, Cardoso-Ortiz, Socorro, Leyva-Ramos, Kim M, Baines, Cesar Fernando Azael, Gómez-Durán, Hiram, Hernández-López, Francisco José, Palacios-Can, José Antonio, Valcarcel-Gamiño, Mario Alberto, Leyva-Peralta, Rodrigo Said, Razo-Hernández
Publikováno v:
Journal of molecular structure. 1274
This study was designed to synthesize hybridizing molecules from ciprofloxacin and norfloxacin by enhancing their biological activity with tetrazoles. The synthesized compounds were investigated in the interaction with the target enzyme of fluoroquin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f00f9f40e63cc18b6de889be3adec48e
https://pubmed.ncbi.nlm.nih.gov/36406777
https://pubmed.ncbi.nlm.nih.gov/36406777
Autor:
Mario Alberto Leyva-Peralta, Socorro Leyva-Ramos, Rodrigo Said Razo-Hernández, Alberto Pedraza-Alvarez, Hiram Hernández-López, Irving Rubén Rodríguez-Gutiérrez, César F. A. Gómez-Durán
Publikováno v:
ACS Omega, Vol 5, Iss 23, Pp 14061-14068 (2020)
Triazoles occupy an important position in medicinal chemistry because of their various biological activities. The structural features of 1,2,3-triazoles enable them to act as a bioisostere of diffe...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee75577437de81e7bc1e3588529e32b6
https://doaj.org/article/9922ce9afd9745b9a9f67293957da96e
https://doaj.org/article/9922ce9afd9745b9a9f67293957da96e