Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Hiraku Mori"'
Autor:
Yosuke Sasaki, Remi Azuma, Yui Uto, Koji Kishimoto, Hiroshi Harada, Hirotsugu Ariizumi, Tomohide Isobe, Eisuke Shiozawa, Masafumi Takimoto, Hiraku Mori, Nobuyuki Ohike
Publikováno v:
Internal Medicine
The pathogenesis of cerebral/renal salt-wasting syndrome remains unknown. We herein present a case of salt-wasting syndrome with a natural killer-cell neoplasm without cerebral invasion. A 78-year-old man with hemophagocytic syndrome received two cyc
Autor:
T Haferlach, Hiraku Mori, Hirotoshi Tanaka, S Miyawaki, Wolfgang Kern, Hitoshi Kiyoi, Yasunobu Nagata, Tetsuichi Yoshizato, Yusuke Shiozawa, Yuichi Shiraishi, Kenichi Yoshida, Claudia Haferlach, Hideki Makishima, Rika Kihara, Shih Ly, Satoru Miyano, Ken Ishiyama, Keisuke Kataoka, H P Koeffler, Aiko Sato-Otsubo, Ayana Kon, Seishi Ogawa, Tomoki Naoe, Masashi Sanada, Tsuyoshi Nakamaki, T. Mori, Kenichi Chiba
Publikováno v:
Leukemia. 30:2270-2273
Leukemia accepted article preview online, 01 August 2016. doi:10.1038/leu.2016.212.
Autor:
Ryuichiro Nakato, Hiraku Mori, Ayana Kon, Seishi Ogawa, Shumpei Ishikawa, Shigeru Chiba, Aiko Nishimoto, Ken Ishiyama, Satoru Miyano, Hiromitsu Nakauchi, Florian Nolte, Masashi Sanada, Katsuhiko Shirahige, Kenichi Yoshida, Tomoyuki Yamaguchi, Claudia Haferlach, Tsuyoshi Nakamaki, Kenichi Chiba, Ryo Yamamoto, Hiroko Tanaka, H. Phillip Koeffler, Teppei Shimamura, Torsten Haferlach, Naoshi Obara, Yusuke Okuno, Masashige Bando, Wolf-Karsten Hofmann, Genta Nagae, Shuichi Miyawaki, Masao Nagasaki, Yuichi Shiraishi, Makoto Otsu, Masashi Minamino, Yusuke Sato, Mamiko Sakata-Yanagimoto, Tamara Alpermann, Lee Yung Shih, Yasunobu Nagata, Daniel Nowak, Aiko Sato-Otsubo, Hiroyuki Aburatani
Publikováno v:
Nature Genetics. 45:1232-1237
Cohesin is a multimeric protein complex that is involved in the cohesion of sister chromatids, post-replicative DNA repair and transcriptional regulation. Here we report recurrent mutations and deletions involving multiple components of the cohesin c
Autor:
Inés Gómez-Seguí, Bartlomiej P Przychodzen, Kenichi Yoshida, Yuichi Shiraishi, Kenichi Chiba, Seiji Kojima, Ronald Paquette, Jaroslaw P. Maciejewski, Hiraku Mori, Mariko Takahashi, Nhu Nguyen, Hiroko Tanaka, Kristbjorn O. Gudmundsson, Satoru Miyano, Michael A. McDevitt, Bandana A. Vishwakarma, Yang Du, Andres Jerez, Masashi Sanada, Kathryn M Guinta, Yogen Saunthararajah, Hideki Muramatsu, Seishi Ogawa, Lee-Yung Shih, Yasunobu Nagata, Mikkael A. Sekeres, Hideki Makishima, Kwok Peng Ng, Hirotoshi Sakaguchi, Yusuke Okuno
Publikováno v:
Nature genetics
Here we report whole-exome sequencing of individuals with various myeloid malignancies and identify recurrent somatic mutations in SETBP1, consistent with a recent report on atypical chronic myeloid leukemia (aCML). Closely positioned somatic SETBP1
Autor:
Masashi Sanada, Hirotaka Matsui, Seishi Ogawa, Shih Ly, Takeshi Ueda, Hiroaki Honda, Norimasa Yamasaki, Toshiya Inaba, Hiraku Mori, Zen-ichiro Honda
Publikováno v:
Leukemia. 26:2557-2560
EED mutants impair polycomb repressive complex 2 in myelodysplastic syndrome and related neoplasms
Autor:
Yutaka Tsuchiya, Hiromi Takayasu, Makoto Hayashi, Sakiko Tazawa, Shogo Tomita, Mami Tada, Takuya Iwasaki, Norikazu Takeda, Fumio Kokubu, Jun Yamashita, Hidetsugu Tateno, Yohei Yamazaki, Aya Wakabayashi, Hiraku Mori
Publikováno v:
Internal Medicine. 51:2411-2415
A 74-year-old Japanese man with myelodysplastic syndrome (MDS) received chemotherapy with azacitidine. From the second day after starting the administration, he complained of fever, cough and shortness of breath. Chest roentgenography and computed to
Autor:
Satoru Miyano, Tomoyuki Yamaguchi, Daniel Nowak, Torsten Haferlach, Wolf-Karsten Hofmann, Shuichi Miyawaki, Florian Nolte, Lee Yung Shih, Mamiko Sakata-Yanagimoto, Makoto Otsu, Hiraku Mori, Masashi Sanada, Naoshi Obara, George Chalkidis, Sumio Sugano, Ayana Kon, Seishi Ogawa, Ken Ishiyama, Yusuke Sato, Shigeru Chiba, Kenichi Yoshida, Masao Nagasaki, Claudia Haferlach, Yuichi Shiraishi, Aiko Sato-Otsubo, Yasunobu Nagata, Yutaka Suzuki, Ryoichiro Kawahata, H. Phillip Koeffler, Masashi Shiosaka, Ryo Yamamoto, Hiromitsu Nakauchi
Publikováno v:
Nature. 478:64-69
Myelodysplastic syndromes and related disorders (myelodysplasia) are a heterogeneous group of myeloid neoplasms showing deregulated blood cell production with evidence of myeloid dysplasia and a predisposition to acute myeloid leukaemia, whose pathog
Autor:
Norimichi Hattori, Kouji Yanagisawa, Hirotsugu Ariizumi, Hiraku Mori, Hiroshi Harada, Yui Uto, Hidetoshi Nakashima, Tsuyoshi Nakamaki, Bungo Saito
Publikováno v:
Bone Marrow Transplantation. 50:301-303
Predictive role of levels of soluble interleukin-2 receptor and C-reactive protein in selecting autologous PBSC transplantation for lymphoma
Autor:
Yasuhide Hayashi, Koji Okamoto, Mineo Kurokawa, Junko Nomoto, Yuichi Ishikawa, Azusa Tamura, Junko Takita, Kumi Nakazaki, Shigeo Mori, Itaru Kato, Tatsutoshi Nakahata, Yukio Kobayashi, Hitoshi Nakagama, Masashi Sanada, Yoshiki Akatsuka, Yoshitaka Asakura, Takashi Igarashi, Mitsuru Iio, Yasuharu Sato, Kensei Tobinai, Akira Niwa, Tadashi Yoshino, Seishi Ogawa, Motohiro Kato, Kengo Takeuchi, Satsuki Muto, Shigeru Chiba, Yuyan Chen, Hiraku Mori
Publikováno v:
Nature. 459:712-716
A20 is a negative regulator of the NF-kappaB pathway and was initially identified as being rapidly induced after tumour-necrosis factor-alpha stimulation. It has a pivotal role in regulation of the immune response and prevents excessive activation of
Autor:
Yui, Uto, Shun, Fujiwara, Nana, Arai, Yukiko, Kawaguchi, Nobuyuki, Kabasawa, Hiroyuki, Tsukamoto, Hirotsugu, Ariizumi, Norimichi, Hattori, Bungo, Saito, Kouji, Yanagisawa, Hiroshi, Harada, Hiraku, Mori, Eisuke, Shiozawa, Tsuyoshi, Nakamaki
Publikováno v:
Rinsho byori. The Japanese journal of clinical pathology. 63(5)
In the present retrospective single-center study, we examined the efficacy and safety of eltrombopag, a thrombopoietin (TPO) -receptor agonist (TPO-RA), and found clinical factors associated with its efficacy in Japanese patients with chronic immune