Výsledky vyhledávání - "Hirakawa Nobuhiko"

A Novel Histamine 2(H2) Receptor Antagonist with Gastroprotective Activity. I. Synthesis and Pharmacological Evaluation of N-Phenoxypropylacetamide Derivatives with Thioether Function

Autor: Tetsuaki Yamaura, Noriaki Kashiwaba, Yasuo Sekine, Matsumoto Hajime, Teruo Kutsuma, Hirakawa Nobuhiko, Akihiro Sekine

Publikováno v: Chemical and Pharmaceutical Bulletin. 46:610-615

In an attempt to develop new types of anti-ulcer agents, a series of N-(phenoxypropyl)acetamide derivatives with a thioether moiety and their sulfur-oxidized analogues were synthesized and evaluated for histamine H2-receptor antagonistic activity, Ca

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe4b38521bd6b70299abe634076bd7b0
https://doi.org/10.1248/cpb.46.610

Zobrazit plný text záznamu

A novel histamine 2(H2) receptor antagonist with gastroprotective activity. II. Synthesis and pharmacological evaluation of 2-furfuryl-thio and 2-furfurylsulfinyl acetamide derivatives with heteroaromatic rings

Autor: Matsumoto Hajime, Akihiko Hosoda, Hirakawa Nobuhiko, Yasuo Sekine, Tetsuaki Yamaura, Akihiro Sekine

Publikováno v: Chemicalpharmaceutical bulletin. 46(4)

We recently found that N-[3-[3-(piperidinomethyl)phenoxyl]propyl]acetamide derivatives with a thioether function showed gastric anti-secretory and gastroprotective activities and that the thioether function (particularly furfurylthio or furfurylsulfi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e82c079637dae8594eca1e4a85244035
https://pubmed.ncbi.nlm.nih.gov/9579037

Zobrazit plný text záznamu