Zobrazeno 1 - 10
of 166
pro vyhledávání: '"Hippokratis Kiaris"'
Autor:
Youwen Zhang, Kim‐Tuyen Huynh‐Dam, Xiaokai Ding, Vitali Sikirzhytski, Chang‐uk Lim, Eugenia Broude, Hippokratis Kiaris
Publikováno v:
FEBS Open Bio, Vol 13, Iss 3, Pp 556-569 (2023)
Evaluation of gene co‐regulation is a powerful approach for revealing regulatory associations between genes and predicting biological function, especially in genetically diverse samples. Here, we applied this strategy to identify transcripts that a
Externí odkaz:
https://doaj.org/article/78b49c7c4a3947dd9a7158a66b36bccd
Autor:
Xiaoling Cao, Vi Nguyen, Joseph Tsai, Chao Gao, Yan Tian, Yuping Zhang, Wayne Carver, Hippokratis Kiaris, Taixing Cui, Wenbin Tan
Publikováno v:
Molecular Metabolism, Vol 74, Iss , Pp 101756- (2023)
Background: As the pandemic evolves, post-acute sequelae of CoV-2 (PASC) including cardiovascular manifestations have emerged as a new health threat. This study aims to study whether the Spike protein plus obesity can exacerbate PASC-related cardiomy
Externí odkaz:
https://doaj.org/article/cb67be5232f1482bae9b8fed5fbe0aa9
Autor:
Juliette Lewis, Shijun Zhan, Allison C. Vilander, Anna C. Fagre, Tawfik A. Aboellail, Hippokratis Kiaris, Tony Schountz
Publikováno v:
Frontiers in Virology, Vol 3 (2023)
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), the virus that causes coronavirus disease-19 (COVID-19), emerged in late 2019 in Wuhan, China and its rapid global spread has resulted in millions of deaths. An important public health con
Externí odkaz:
https://doaj.org/article/f365c4a19b71497390dac11920d27693
Autor:
Asieh Naderi, Elena Farmaki, Bernardo Chavez, Chao Cai, Vimala Kaza, Youwen Zhang, Elham Soltanmohammadi, Nina Daneshvar, Ioulia Chatzistamou, Hippokratis Kiaris
Publikováno v:
iScience, Vol 25, Iss 12, Pp 105520- (2022)
Summary: CCL8 (MCP-2) is a chemoattractive cytokine associated with various immune-related pathologies. Recent studies show that CCL8 is significantly stimulated during acute respiratory distress syndrome in severely ill patients with COVID-19, makin
Externí odkaz:
https://doaj.org/article/62f144da7466462db9393b1a954b75a3
Autor:
Matthew D. Lucius, Hao Ji, Diego Altomare, Robert Doran, Ben Torkian, Amanda Havighorst, Vimala Kaza, Youwen Zhang, Alexander V. Gasparian, Joseph Magagnoli, Vijay Shankar, Michael Shtutman, Hippokratis Kiaris
Publikováno v:
BMC Genomics, Vol 22, Iss 1, Pp 1-15 (2021)
Abstract Background Deer mice (genus Peromyscus) are the most common rodents in North America. Despite the availability of reference genomes for some species, a comprehensive database of polymorphisms, especially in those maintained as living stocks
Externí odkaz:
https://doaj.org/article/624683376d8644fd929c9ec0c3cdc625
Publikováno v:
BMC Genomics, Vol 22, Iss 1, Pp 1-12 (2021)
Abstract Background Deregulation in lipid metabolism leads to the onset of hepatic steatosis while at subsequent stages of disease development, the induction of inflammation, marks the transition of steatosis to non-alcoholic steatohepatitis. While d
Externí odkaz:
https://doaj.org/article/20bfc798f06340a88f7e730c6d93bd0a
Autor:
Youwen Zhang, Chang-uk Lim, Vitali Sikirzhytski, Asieh Naderi, Ioulia Chatzistamou, Hippokratis Kiaris
Publikováno v:
Disease Models & Mechanisms, Vol 14, Iss 10 (2021)
The unfolded protein response (UPR) is involved in the pathogenesis of metabolic disorders, yet whether variations in the UPR among individuals influence the propensity for metabolic disease remains unexplored. Using outbred deer mice as a model, we
Externí odkaz:
https://doaj.org/article/9130226894f149c9ab691b4383d16a08
Autor:
Vi Nguyen, Yuping Zhang, Chao Gao, Xiaoling Cao, Yan Tian, Wayne Carver, Hippokratis Kiaris, Taixing Cui, Wenbin Tan
Publikováno v:
Cells, Vol 11, Iss 12, p 1916 (2022)
Coronavirus disease 2019 (COVID-19) patients show lipid metabolic alterations, but the mechanism remains unknown. In this study, we aimed to investigate whether the Spike protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) impairs
Externí odkaz:
https://doaj.org/article/8a599dca5d6847f3bb6021b79be3aef2
Autor:
Asieh Naderi, Elham Soltanmaohammadi, Vimala Kaza, Shayne Barlow, Ioulia Chatzistamou, Hippokratis Kiaris
Publikováno v:
eLife, Vol 10 (2021)
Epidemiological evidence suggests that social interactions and especially bonding between couples influence tumorigenesis, yet whether this is due to lifestyle changes, homogamy (likelihood of individuals to marry people of similar health), or direct
Externí odkaz:
https://doaj.org/article/18d703f347044dca8d5dc3a327e82faf
Autor:
Gabriela Balderrama-Gutierrez, Ana Milovic, Vanessa J. Cook, M. Nurul Islam, Youwen Zhang, Hippokratis Kiaris, John T. Belisle, Ali Mortazavi, Alan G. Barbour
Publikováno v:
mBio, Vol 12, Iss 2 (2021)
Animals that are natural carriers of pathogens that cause human diseases commonly manifest little or no sickness as a consequence of infection. Examples include the deer mouse, Peromyscus leucopus
Externí odkaz:
https://doaj.org/article/7cae09109398440b9c71dc64b214614b