Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Hippocampus/drug effects"'
Autor:
Tatyana Strekalova, Dmitrii Pavlov, Alexander Trofimov, Daniel C. Anthony, Andrei Svistunov, Andrey Proshin, Aleksei Umriukhin, Alexei Lyundup, Klaus-Peter Lesch, Raymond Cespuglio
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 4; Pages: 2061
International journal of molecular sciences, 23(4):2061. Multidisciplinary Digital Publishing Institute (MDPI)
International journal of molecular sciences, 23(4):2061. Multidisciplinary Digital Publishing Institute (MDPI)
The phenomenon of individual variability in susceptibility/resilience to stress and depression, in which the hippocampus plays a pivotal role, is attracting increasing attention. We investigated the potential role of hippocampal cyclooxygenase-2 (COX
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7456a3942259e959028d66480202f45c
https://pubmed.ncbi.nlm.nih.gov/35216176
https://pubmed.ncbi.nlm.nih.gov/35216176
Publikováno v:
Progress in Neurobiology
Progress in Neurobiology, Elsevier, 2020, 194, pp.101888-. ⟨10.1016/j.pneurobio.2020.101888⟩
Progress in neurobiology, vol. 194, pp. 101888
Progress in Neurobiology, Elsevier, 2020, 194, pp.101888-. ⟨10.1016/j.pneurobio.2020.101888⟩
Progress in neurobiology, vol. 194, pp. 101888
Brain lactate formation, intercellular exchange and utilization has been implicated in memory formation. However, the individual role of either neuronal or astroglial monocarboxylate transporters for the acquisition and consolidation of information r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edf17c3cb032d051faa32a907a9d81a6
https://hal.archives-ouvertes.fr/hal-03493008
https://hal.archives-ouvertes.fr/hal-03493008
Autor:
Joilson Ramos-Jesus, Jand Venes R. Medeiros, André Luis Fernandes Lopes, Marcelo P. Bemquerer, Guilherme Antônio Lopes de Oliveira, Renato Socodato, Nayara A. Sousa, Luan Kelves Miranda de Souza, Eder Alves Barbosa, Thiago S.L. Araújo, Camila C. Portugal, Kerolayne M. Nogueira, Bruno Iles, Peter Eaton, Alexandra Plácido, Andrea Lobo, Alyne Rodrigues de Araújo, João B. Relvas, Yuri D. M. Campelo, José Roberto S. A. Leite, Ana Patrícia de Oliveira, Constança Pais do Amaral
Publikováno v:
Repositório Institucional da EMBRAPA (Repository Open Access to Scientific Information from EMBRAPA-Alice)
Empresa Brasileira de Pesquisa Agropecuária (Embrapa)
instacron:EMBRAPA
Scientific Reports, Vol 10, Iss 1, Pp 1-16 (2020)
Scientific Reports
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Empresa Brasileira de Pesquisa Agropecuária (Embrapa)
instacron:EMBRAPA
Scientific Reports, Vol 10, Iss 1, Pp 1-16 (2020)
Scientific Reports
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
© The Author(s) 2020. Open Access. This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c936432f2390466bc43188ee5504a1e8
https://hdl.handle.net/10451/47101
https://hdl.handle.net/10451/47101
Autor:
Norberto Peporine Lopes, José Luiz Liberato, Wagner Ferreira dos Santos, Andréia Cristina Karklin Fontana, Márcia Renata Mortari, Lívea Dornela Godoy, Rene Oliveira Beleboni, Alexandra Olimpio Siqueira Cunha
Publikováno v:
Liberato, J L, Godoy, L D, Cunha, A O S, Mortari, M R, de Oliveira Beleboni, R, Fontana, A C K, Lopes, N P & Dos Santos, W F 2018, ' Parawixin2 Protects Hippocampal Cells in Experimental Temporal Lobe Epilepsy ', Toxins, vol. 10, no. 12 . https://doi.org/10.3390/toxins10120486
Toxins
Volume 10
Issue 12
Toxins, Vol 10, Iss 12, p 486 (2018)
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Toxins
Volume 10
Issue 12
Toxins, Vol 10, Iss 12, p 486 (2018)
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Epilepsy is considered as one of the major disabling neuropathologies. Almost one third of adult patients with temporal lobe epilepsy (TLE) do not respond to current antiepileptic drugs (AEDs). Additionally, most AEDs do not have neuroprotective effe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3096ed9933f144a5d7e7a6a79dde8d63
https://pure.au.dk/portal/da/publications/parawixin2-protects-hippocampal-cells-in-experimental-temporal-lobe-epilepsy(70f8b237-7f34-40b0-ab6b-2df7336832bd).html
https://pure.au.dk/portal/da/publications/parawixin2-protects-hippocampal-cells-in-experimental-temporal-lobe-epilepsy(70f8b237-7f34-40b0-ab6b-2df7336832bd).html
Autor:
Konstantin Drandarov, Matthias T. Wyss, Ximena Castillo, Katia Rosafio, Lorenz Hirt, Alfred Buck, Luc Pellerin, Bruno Weber
Publikováno v:
Journal of Cerebral Blood Flow and Metabolism, vol. 35, no. 10, pp. 1561-1569
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, vol. 35, no. 10, pp. 1561-1569
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, vol. 35, no. 10, pp. 1561-1569
Lactate has been shown to offer neuroprotection in several pathologic conditions. This beneficial effect has been attributed to its use as an alternative energy substrate. However, recent description of the expression of the HCA1 receptor for lactate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08dddf3aed83e7117e18885227349575
https://doi.org/10.1038/jcbfm.2015.115
https://doi.org/10.1038/jcbfm.2015.115
Autor:
Judith Blanz, Paul Saftig, Stijn Stroobants, Ann Van der Jeugd, Rudi D'Hooge, Markus Damme, Ben Vermaercke, Claes Andersson, Jens Fogh
Publikováno v:
Neurobiology of Disease, Vol 106, Iss, Pp 255-268 (2017)
Alpha-mannosidosis is a glycoproteinosis caused by deficiency of lysosomal acid alpha-mannosidase (LAMAN), which markedly affects neurons of the central nervous system (CNS), and causes pathognomonic intellectual dysfunction in the clinical condition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9efa1f42341ae0f754812c573cc09580
https://doi.org/10.1016/j.nbd.2017.07.013
https://doi.org/10.1016/j.nbd.2017.07.013
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Stanquini, L A, Biojone, C, Guimarães, F S & Joca, S R 2018, ' Repeated treatment with nitric oxide synthase inhibitor attenuates learned helplessness development in rats and increases hippocampal BDNF expression ' Acta Neuropsychiatrica, vol. 30, no. 3, pp. 127-136 . https://doi.org/10.1017/neu.2017.28
Universidade de São Paulo (USP)
instacron:USP
Stanquini, L A, Biojone, C, Guimarães, F S & Joca, S R 2018, ' Repeated treatment with nitric oxide synthase inhibitor attenuates learned helplessness development in rats and increases hippocampal BDNF expression ' Acta Neuropsychiatrica, vol. 30, no. 3, pp. 127-136 . https://doi.org/10.1017/neu.2017.28
BackgroundNitric oxide synthase (NOS) inhibitors induce antidepressant-like effects in animal models sensitive to acute drug treatment such as the forced swimming test. However, it is not yet clear if repeated treatment with these drugs is required t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54bbf826880a6ebc2ee5d73b8fd4ba5d
Publikováno v:
Vitamins and hormones. 82:421-431
Adult hippocampal neurogenesis is decreased in rodent models for stress-related disorders partly through an elevated level of glucocorticoids (GCs). On the other hand, lithium (Li), a mood stabilizer and an inhibitor of GSK-3beta, increases adult hip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=jairo_______::a1e10bc87801694f68dcb5e814f3cd7e
http://hdl.handle.net/2115/50394
http://hdl.handle.net/2115/50394
Autor:
Lorenz Hirt, Carole Berthet, Pierre J. Magistretti, Jonathan Thevenet, Rolf Gruetter, Hongxia Lei
Publikováno v:
Journal of Cerebral Blood Flow and Metabolism, Vol. 29, No 11 (2009) pp. 1780-9
It is well established that lactate can be used as an energy substrate by the brain by conversion to pyruvate and a subsequent oxidation in the mitochondria. Knowing the need for readily metabolizable substrates directly after ischemia and the protec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f44a27295ebc627e3df6ddbfec16f84
https://doi.org/10.1038/jcbfm.2009.97
https://doi.org/10.1038/jcbfm.2009.97
Autor:
Yonguc GN, Dodurga Y, Adiguzel E, Gundogdu G, Kucukatay V, Ozbal S, Yilmaz I, Cankurt U, Yilmaz Y, Akdogan I
We aimed to investigate the effects of grape seed extract (GSE) and vitamin E (Vit E) on oxidative stress and apoptosis in the hippocampus of streptozotocin-induced diabetic rats. In Control, Diabetic, and Diabetic treated with GSE (Diabetic+GSE) and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______3566::93f621dc7a062689835711fd4c7ff274