Výsledky vyhledávání - "Hippocampus/cytology/metabolism"

Sequential implication of the mental retardation proteins ARHGEF6 and PAK3 in spine morphogenesis

Autor: Dominique Muller, Roxanne Node-Langlois, Bernadett Boda

Publikováno v: Journal of Cell Science, Vol. 119, No Pt 23 (2006) pp. 4986-4993

The biological mechanisms underlying the mental retardation associated with mutation of the ARHGEF6 gene, a Rac1/Cdc42 exchange factor, are still unknown, although defects in the plasticity of synaptic networks have been postulated. We have cloned th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb6d7502d8c58ca25720967f45e4d363
https://doi.org/10.1242/jcs.03273

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Nonsense-Mediated mRNA Decay and Loss-of-Function of the Protein Underlie the X-Linked Epilepsy Associated with the W356x Mutation in Synapsin I

Autor: Niels H. Gehring, Flavia Valtorta, Maila Giannandrea, Fabio Benfenati, Fabrizia C. Guarnieri, Andreas E. Kulozik, Elena Monzani

Publikováno v: PLoS ONE
PLoS ONE, Vol 8, Iss 6, p e67724 (2013)

Synapsins are a family of neuronal phosphoproteins associated with the cytosolic surface of synaptic vesicles. Experimental evidence suggests a role for synapsins in synaptic vesicle clustering and recycling at the presynaptic terminal, as well as in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45420da1b91a69ecf51646a401a32f61
http://hdl.handle.net/11567/698004

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Targeting pannexin1 improves seizure outcome

Autor: Anne Charollais, Dorothée Caille, Naman K. Patel, Paolo Meda, Eliana Scemes, Marcelo F. Santiago, Sarah E. Lutz, Jana Velíšková

Publikováno v: PLOS ONE, Vol. 6, No 9 (2011) P. e25178
PLoS ONE
PLoS ONE, Vol 6, Iss 9, p e25178 (2011)
PloS one
PLoS ONE; Vol 6

Imbalance of the excitatory neurotransmitter glutamate and of the inhibitory neurotransmitter GABA is one of several causes of seizures. ATP has also been implicated in epilepsy. However, little is known about the mechanisms involved in the release o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca1d9067a0c401fd204e0ac3a5c9ca63
https://archive-ouverte.unige.ch/unige:24824

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Influence of matrix metalloproteinase MMP-9 on dendritic spine morphology

Autor: Paulina Wyrembek, Marcin Wawrzyniak, Nikolay I. Medvedev, Leszek Kaczmarek, Grzegorz M. Wilczynski, Dominique Muller, Marcin Szczot, Jerzy W. Mozrzymas, Ewa Wilczek, Katarzyna Mercik, Mathias De Roo, Michael G. Stewart, Jakub Wlodarczyk, Przemyslaw Alot, Werner Zuschratter, Piotr Michaluk

Publikováno v: Journal of Cell Science, Vol. 124, No Pt 19 (2011) pp. 3369-80
Journal of cell science
Journal of Cell Science; Vol 124

An increasing body of data has shown that matrix metalloproteinase-9 (MMP-9), an extracellularly acting, Zn2+-dependent endopeptidase, is important not only for pathologies of the central nervous system but also for neuronal plasticity. Here, we use

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b15b6df20bdee0d90b3278c35c334769
https://archive-ouverte.unige.ch/unige:25597

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New interneurons in the adult neocortex: small, sparse, but significant?

Autor: Alexandre Dayer, Heather A. Cameron

Publikováno v: Biological Psychiatry, Vol. 63, No 7 (2008) pp. 650-5

During the last decade, the intense study of adult hippocampal neurogenesis has led to several new lines of inquiry in the field of psychiatry. Although it is generally believed that adult mammalian neurogenesis is restricted to the hippocampus and o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84dc6194942ab3be3ed7a0177f75a829
https://pubmed.ncbi.nlm.nih.gov/18067877

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The oxytocin-induced inward current in vagal neurons of the rat is mediated by G protein activation but not by an increase in the intracellular calcium concentration

Autor: Jean Jacques Dreifuss, Mario Raggenbass, Stefano Alberi

Publikováno v: European Journal of Neuroscience, Vol. 9, No 12 (1997) pp. 2605-2612

The neuropeptide oxytocin can depolarize parasympathetic preganglionic neurons in the dorsal motor nucleus of the vagus nerve of the rat by generating a sustained inward current, which is sodium-dependent and tetrodotoxin-insensitive. The second mess

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a4dea4205900da36dd7b65b3d184c78
https://archive-ouverte.unige.ch/unige:10157

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