Zobrazeno 1 - 10
of 4 924
pro vyhledávání: '"Hippocampal slices"'
Autor:
Carla Nunes, João Laranjinha
Publikováno v:
BioChem, Vol 3, Iss 2, Pp 78-90 (2023)
Nitric oxide (•NO), a diffusible free radical, is an intercellular messenger, playing a crucial role in several key brain physiological processes, including in neurovascular coupling (NVC). In the brain, glutamatergic activation of the neuronal nit
Externí odkaz:
https://doaj.org/article/44f60173952b4f5ba6f6f2cf6e37fb73
Akademický článek
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Autor:
Nicholas Guerini Selistre, Leticia Rodrigues, Barbara Carolina Federhen, Vitor Gayger-Dias, Jéssica Taday, Krista Mineia Wartchow, Carlos-Alberto Gonçalves
Publikováno v:
Metabolites, Vol 14, Iss 1, p 7 (2023)
S100B is a calcium-binding protein produced and secreted by astrocytes in response to various extracellular stimuli. C6 glioma cells are a lineage commonly employed for astroglial studies due to the expression of astrocyte specific markers and behavi
Externí odkaz:
https://doaj.org/article/14d34baefac041e3b0454e88488b1ce4
Akademický článek
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Autor:
Elisa Landucci, Costanza Mazzantini, Daniele Lana, Maura Calvani, Giada Magni, Maria Grazia Giovannini, Domenico E. Pellegrini-Giampietro
Publikováno v:
Neurobiology of Disease, Vol 174, Iss , Pp 105895- (2022)
Background: Epilepsy is one of the most common brain disorder and, despite the possible use of several therapeutic options, many patients continue to have seizures for their entire lifespan and they need new therapeutic approaches. In the last years
Externí odkaz:
https://doaj.org/article/150f3b938b9d427ba6e0e6839029d473
Akademický článek
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Autor:
Martina Venturini, Federica Cherchi, Clara Santalmasi, Lucia Frulloni, Ilaria Dettori, Daniela Catarzi, Felicita Pedata, Vittoria Colotta, Flavia Varano, Elisabetta Coppi, Anna Maria Pugliese
Publikováno v:
Biomolecules, Vol 13, Iss 6, p 894 (2023)
In recent years, the use of multi-target compounds has become an increasingly pursued strategy to treat complex pathologies, including cerebral ischemia. Adenosine and its receptors (A1AR, A2AAR, A2BAR, A3AR) are known to play a crucial role in synap
Externí odkaz:
https://doaj.org/article/967ca781ef344086a54e640f6929530b
Publikováno v:
Neurobiology of Disease, Vol 168, Iss , Pp 105712- (2022)
Methamphetamine (Meth) abuse and human immunodeficiency virus type 1 (HIV-1) infection are two major public health problems worldwide. Being frequently comorbid with HIV-1 infection, Meth abuse exacerbates neurocognitive impairment in HIV-1-infected
Externí odkaz:
https://doaj.org/article/7e24758537934c2ebece03419140f4c1
Publikováno v:
Energy Reports, Vol 6, Iss , Pp 286-291 (2020)
Energy for life is produced inside the internal human energy factory, the mitochondrion, where low oxygen levels are likely to be correlated with stressful behaviors. These include thriving for performance, competition and perfection. One way to buil
Externí odkaz:
https://doaj.org/article/bc59571f44c1464fafc996457ed25f65
Publikováno v:
Molecular Brain, Vol 13, Iss 1, Pp 1-10 (2020)
Abstract Information processing and memory formation in the brain relies on release of the main excitatory neurotransmitter glutamate from presynaptic axonal specialisations. The classical Hebbian paradigm of synaptic memory, long-term potentiation (
Externí odkaz:
https://doaj.org/article/0732e4e3ae39478aa5d1b9eec6134aeb