Zobrazeno 1 - 10
of 382
pro vyhledávání: '"Hippo–YAP pathway"'
Autor:
Zhengyan Chang, Runzhi Huang, Jiaqi Song, Zhenyu Li, Man Pi, Shuyuan Xian, Jingcheng Zhang, Jinglei Huang, Ruting Xie, Guo Ji, Dongyan Han, Qiongyi Huang
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-18 (2024)
Abstract Background Colon adenocarcinoma (COAD) ranks as the third most prevalent and lethal cancer in 2020, with metastasis being the primary cause of cancer-related mortality. A comprehensive understanding of the mechanism underlying distant metast
Externí odkaz:
https://doaj.org/article/1d1d9d8a12134505995bfbfe9fe21153
Autor:
Xiaowen Zhu, Pengxia Zhang
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-16 (2024)
Abstract Background Recent evidence has demonstrated the vital roles of circular RNAs (circRNAs) in the progression of colorectal cancer (CRC); however, their functions and mechanisms in CRC need to be further explored. This study aimed to uncover th
Externí odkaz:
https://doaj.org/article/1f324f3bc2fb48db959e1be0e5f363b9
Autor:
Cho-Long Kim, Su-Bin Lim, Dong Hyun Kim, Ye Eun Sim, Li-Jung Kang, Su Jung Park, Hyungwoo Kim, Tae Hoon Roh, Jung-Soon Mo, Han-Sol Jeong
Publikováno v:
Translational Oncology, Vol 46, Iss , Pp 101971- (2024)
Cholangiocarcinoma (CCA) is a devastating malignancy characterized by aggressive tumor growth and limited treatment options. Dysregulation of the Hippo signaling pathway and its downstream effector, Yes-associated protein (YAP), has been implicated i
Externí odkaz:
https://doaj.org/article/bf71932560d04652b65216cc8f13714d
Publikováno v:
Cells, Vol 13, Iss 16, p 1342 (2024)
From birth to adulthood, the mammalian heart grows primarily through increasing cardiomyocyte (CM) size, which is known as maturational hypertrophic growth. The Hippo-YAP signaling pathway is well known for regulating heart development and regenerati
Externí odkaz:
https://doaj.org/article/ca044dfa2e164160ab1bedc2fc8cce88
Autor:
Xi Ran, Sabine Müller, Coy Brunssen, Robert Huhle, Martin Scharffenberg, Christian Schnabel, Thea Koch, Marcelo Gama de Abreu, Henning Morawietz, Jorge M. C. Ferreira, Jakob Wittenstein
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Background: Mechanical ventilation (MV) is a life supporting therapy but may also cause lung damage. This phenomenon is known as ventilator-induced lung injury (VILI). A potential pathomechanisms of ventilator-induced lung injury may be the stretch-i
Externí odkaz:
https://doaj.org/article/feb974d320a6413b9dd741435a3ddb89
Akademický článek
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Akademický článek
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Akademický článek
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Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
Disruption of iron homeostasis plays a negative role in follicle development. The dynamic changes in follicle growth are dependent on Hippo/YAP signaling and mechanical forces. However, little is known about the liaison between iron overload and the
Externí odkaz:
https://doaj.org/article/06760c335f134650b1941fa2ad858649
Publikováno v:
Genetics and Molecular Biology, Vol 46, Iss 1 (2023)
Abstract Mesenchymal stem cells-derived exosomes (MSCs-exosomes) reportedly possess cardioprotective effects. This study investigated the therapeutic potential and mechanisms of MSCs-exosomes on heart failure (HF). H9c2 cells were used to establish a
Externí odkaz:
https://doaj.org/article/dd75786010804fadadccba1803085737