Zobrazeno 1 - 10
of 28
pro vyhledávání: '"HipSci Consortium"'
Autor:
Anna S. E. Cuomo, Daniel D. Seaton, Davis J. McCarthy, Iker Martinez, Marc Jan Bonder, Jose Garcia-Bernardo, Shradha Amatya, Pedro Madrigal, Abigail Isaacson, Florian Buettner, Andrew Knights, Kedar Nath Natarajan, HipSci Consortium, Ludovic Vallier, John C. Marioni, Mariya Chhatriwala, Oliver Stegle
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Studying the genetic effects on early stages of human development is challenging due to a scarcity of biological material. Here, the authors utilise induced pluripotent stem cells from 125 donors to track gene expression changes and expression quanti
Externí odkaz:
https://doaj.org/article/a7b1f1030ed944ff83690e903da90113
Autor:
Bogdan Andrei Mirauta, Daniel D Seaton, Dalila Bensaddek, Alejandro Brenes, Marc Jan Bonder, Helena Kilpinen, HipSci Consortium, Oliver Stegle, Angus I Lamond
Publikováno v:
eLife, Vol 9 (2020)
Human disease phenotypes are driven primarily by alterations in protein expression and/or function. To date, relatively little is known about the variability of the human proteome in populations and how this relates to variability in mRNA expression
Externí odkaz:
https://doaj.org/article/8691ab25bec342bdb91e9f291b408ea7
Autor:
William B. Barrell, John N. Griffin, Jessica-Lily Harvey, HipSci Consortium, Davide Danovi, Philip Beales, Agamemnon E. Grigoriadis, Karen J. Liu, Richard Durbin, Daniel Gaffney, Chukwuma Agu, Alex Alderton, Shrada Amatya, Petr Danecek, Rachel Denton, Angela Goncalves, Reena Halai, Sarah Harper, Chris Kirton, Andrew Knights, Anja Kolb-Kokocinski, Andreas Leha, Shane McCarthy, Yasin Memari, Minal Patel, Ewan Birney, Oliver Stegle, Francesco Paolo Casale, Laura Clarke, Peter Harrison, Helena Kilpinen, Davis McCarthy, Ian Streeter, Fiona Watt, Davide Denovi, Ruta Meleckyte, Natalie Moens, Willem Ouwehand, Ludovic Vallier, Angus Lamond, Dalila Bensaddek
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 12 (2019)
Neural crest cells arise in the embryo from the neural plate border and migrate throughout the body, giving rise to many different tissue types such as bones and cartilage of the face, smooth muscles, neurons, and melanocytes. While studied extensive
Externí odkaz:
https://doaj.org/article/3dc064c4ac76449b82dd6ccf0dc8ab8c
Autor:
Anna S. E. Cuomo, Daniel D. Seaton, Davis J. McCarthy, Iker Martinez, Marc Jan Bonder, Jose Garcia-Bernardo, Shradha Amatya, Pedro Madrigal, Abigail Isaacson, Florian Buettner, Andrew Knights, Kedar Nath Natarajan, HipSci Consortium, Ludovic Vallier, John C. Marioni, Mariya Chhatriwala, Oliver Stegle
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-1 (2020)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/a8a149af37a3453ea2499263f7e30501
Publikováno v:
PLoS ONE, Vol 11, Iss 5, p e0155014 (2016)
Genomic screening for chromosomal abnormalities is an important part of quality control when establishing and maintaining stem cell lines. We present a new method for sensitive detection of copy number alterations, aneuploidy, and contamination in ce
Externí odkaz:
https://doaj.org/article/cb9d02201bc24de197b46f514243cb4b
Autor:
Jerber, Julie, Seaton, Daniel D, Cuomo, Anna SE, Kumasaka, Natsuhiko, Haldane, James, Steer, Juliette, Patel, Minal, Pearce, Daniel, Andersson, Malin, Bonder, Marc Jan, Mountjoy, Ed, Ghoussaini, Maya, Lancaster, Madeline A, HipSci Consortium, Marioni, John C, Merkle, Florian T, Gaffney, Daniel J, Stegle, Oliver
Studying the function of common genetic variants in primary human tissues and during development is challenging. To address this, we use an efficient multiplexing strategy to differentiate 215 human induced pluripotent stem cell (iPSC) lines toward a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23b5e899f077fa7945ddbd9ea6e8e4c5
https://www.repository.cam.ac.uk/handle/1810/316050
https://www.repository.cam.ac.uk/handle/1810/316050
Akademický článek
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Akademický článek
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Akademický článek
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Autor:
HipSci Consortium
Neural crest cells arise in the embryo from the neural plate border and migrate throughout the body, giving rise to many different tissue types such as bones and cartilage of the face, smooth muscles, neurons, and melanocytes. While studied extensive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1366::19d90698794af11d82fc3f967720b249
https://ueaeprints.uea.ac.uk/id/eprint/73795/
https://ueaeprints.uea.ac.uk/id/eprint/73795/