Mechanistic Characterization of Cancer-associated Fibroblast Depletion via an Antibody-Drug Conjugate Targeting Fibroblast Activation Protein.

Autor: Gallant JP; Molecular and Cellular Pharmacology Program, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin.; Department of Pathology and Laboratory Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin., Hintz HM; Department of Pharmacology, University of Minnesota School of Medicine, Minneapolis, Minnesota., Gunaratne GS; Department of Pathology and Laboratory Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin., Breneman MT; Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin.; University of Wisconsin Carbone Cancer Center, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin., Recchia EE; Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin.; University of Wisconsin Carbone Cancer Center, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin., West JL; Molecular and Cellular Pharmacology Program, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin.; Department of Pathology and Laboratory Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin., Ott KL; Molecular and Cellular Pharmacology Program, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin.; Department of Pathology and Laboratory Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin., Heninger E; Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin.; University of Wisconsin Carbone Cancer Center, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin., Jackson AE; Department of Pathology and Laboratory Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin., Luo NY; Department of Pathology and Laboratory Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin., Rosenkrans ZT; Department of Medical Physics, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin., Hernandez R; Department of Medical Physics, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin.; Department of Radiology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin., Zhao SG; University of Wisconsin Carbone Cancer Center, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin.; Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin., Lang JM; Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin.; University of Wisconsin Carbone Cancer Center, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin., Meimetis L; Department of Radiology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin., Kosoff D; Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin.; University of Wisconsin Carbone Cancer Center, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin.; William S Middleton Memorial Veterans' Hospital, Madison, Wisconsin., LeBeau AM; Department of Pathology and Laboratory Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin.; University of Wisconsin Carbone Cancer Center, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin.; Department of Radiology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin.

Publikováno v: Cancer research communications [Cancer Res Commun] 2024 Jun 12; Vol. 4 (6), pp. 1481-1494.

Imaging Fibroblast Activation Protein Alpha Improves Diagnosis of Metastatic Prostate Cancer with Positron Emission Tomography.

Autor: Hintz HM; Department of Pharmacology, University of Minnesota Medical School, Minneapolis, Minnesota., Gallant JP; Department of Pharmacology, University of Minnesota Medical School, Minneapolis, Minnesota., Vander Griend DJ; Department of Pathology and Surgery, University of Illinois at Chicago, Chicago, Illinois., Coleman IM; Division of Human Biology and Clinical Research, Fred Hutchinson Cancer Research Center, Seattle, Washington., Nelson PS; Division of Human Biology and Clinical Research, Fred Hutchinson Cancer Research Center, Seattle, Washington., LeBeau AM; Department of Pharmacology, University of Minnesota Medical School, Minneapolis, Minnesota. alebeau@umn.edu.

Publikováno v: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2020 Sep 15; Vol. 26 (18), pp. 4882-4891. Date of Electronic Publication: 2020 Jul 07.

A screening campaign in sea urchin egg homogenate as a platform for discovering modulators of NAADP-dependent Ca ²⁺ signaling in human cells.

Autor: Gunaratne GS; Department of Pharmacology, University of Minnesota Medical School, MN 55455, USA., Johns ME; Department of Pharmacology, University of Minnesota Medical School, MN 55455, USA., Hintz HM; Department of Pharmacology, University of Minnesota Medical School, MN 55455, USA., Walseth TF; Department of Pharmacology, University of Minnesota Medical School, MN 55455, USA., Marchant JS; Department of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, Milwaukee WI 53226, USA. Electronic address: JMarchant@mcw.edu.

Publikováno v: Cell calcium [Cell Calcium] 2018 Nov; Vol. 75, pp. 42-52. Date of Electronic Publication: 2018 Aug 16.