Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Hinrik Strömer"'
Autor:
Hinrik Strömer, Mark C. H. de Groot, Michael Horn, Christian Faul, Andrea Leupold, James P. Morgan, Wolfgang Scholz, Stefan Neubauer
Publikováno v:
Scopus-Elsevier
Background —Na + /H + exchange inhibition with HOE642 (cariporide) improves postischemic recovery of cardiac function, but the mechanisms of action remain speculative. Because Na + /H + exchange is activated on reperfusion, it was hypothesized that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f44683698d8ae72ae468b9786ccd6cb7
https://ora.ox.ac.uk/objects/uuid:c422bce6-1eaf-4a76-8953-0b626911393d
https://ora.ox.ac.uk/objects/uuid:c422bce6-1eaf-4a76-8953-0b626911393d
Publikováno v:
Herz. 31:455-468
More than 15,000 valve replacements are annually performed in Germany resulting in a significant improvement of function, symptoms and prognosis. Nevertheless, prosthetic heart valves bear a small risk of serious complications and these patients rema
Autor:
Klaus Meyer, Ernest A. Boehm, Helga Wagner, Stefan Neubauer, Matthias Spindler, Hinrik Strömer, Andrea Leupold
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 287:H1039-H1045
The creatine kinase (CK) system is involved in the rapid transport of high-energy phosphates from the mitochondria to the sites of maximal energy requirements such as myofibrils and sarcolemmal ion pumps. Hearts of mice with a combined knockout of cy
Autor:
Robert H. G. Schwinger, Andreas Bonz, Birgit Bölck, Andrea Leupold, Frank Callies, Bruno Allolio, Stefan Frantz, Stephanie Beer, Kai Hu, Hinrik Strömer
Publikováno v:
Endocrinology. 144:4478-4483
This study investigated the impact of testosterone on myocardial ischemia-reperfusion injury and corresponding intracellular calcium ([Ca2+]i) metabolism. Nonorchiectomized mature male Wistar rats were randomly assigned to placebo, a single dose of t
Autor:
Antonio Cittadini, Lavinia Saldamarco, Cosma Casaburi, Raffaella Serpico, Angela Di Gianni, Maria Chiara Monti, Luigi Saccà, Jörgen Isgaard, Massimo Vanasia, Hinrik Strömer
Publikováno v:
Cardiovascular Research. 58:555-564
Objectives: To investigate the effects of aldosterone receptor blockade in postinfarction heart failure. Methods: Eighty-seven rats with moderate myocardial infarction were randomized to receive either no drug or canrenone, the active metabolite of s
Autor:
Pamela S. Douglas, Hinrik Strömer, Sarah Katz, James P. Morgan, Jessica D. Grossman, Antonio Cittadini
Publikováno v:
Endocrinology. 142:332-338
Treatment with GH attenuates remodeling and improves left ventricular function in the setting of experimental heart failure following coronary ligation. This study was designed to test the hypothesis that an intact GH/insulin-like growth factor 1 (IG
Autor:
Joanne S. Ingwall, Ross G. Clark, Yoshiki Ishiguro, Antonio Cittadini, Pamela S. Douglas, Matthias Spindler, Hinrik Strömer, James P. Morgan, Alan C. Moses
Publikováno v:
Circulation Research. 83:50-59
Abstract —A growing body of evidence has been accumulated recently suggesting that growth hormone (GH) and insulin-like growth factor-1 (IGF-1) affect cardiac function, but their mechanism(s) of action is unclear. In the present study, GH and IGF-1
Autor:
Antonio Cittadini, Hinrik Strömer, Dorothy E. Vatner, Jessica D. Grossman, Sarah E. Katz, Ross Clark, James P. Morgan, Pamela S. Douglas
Publikováno v:
Endocrinology. 138:5161-5169
To evaluate GH’s role in cardiac physiology and its interrelationship with the β-adrenergic system, we studied GH-deficient dwarf (dw/dw) and control rats in 4 groups of 20 each: dwarf group receiving placebo, dwarf-GH group receiving 2 mg/kg GH,
Autor:
Pamela S. Douglas, Hinrik Strömer, Sarah E. Katz, Robert J. Smith, Antonio Cittadini, Ross G. Clark, James P. Morgan, Raffaele Napoli, Jessica D. Grossman
Publikováno v:
Journal of the American College of Cardiology. 29(5):1109-1116
Objectives. We sought to investigate the cardiac effects of growth hormone (GH) administration during the early phase of pathologic remodeling in a rat model of large myocardial infarction (MI).Background. Recent evidence suggests that exogenous admi
Publikováno v:
Circulation Research. 79:227-236
It has been proposed that chronic treatment with growth hormone (GH) or insulin-like growth factor-I (IGF-I) in the rat may enhance cardiac function in vivo. To confirm these findings and elucidate the mechanisms by which cardiac function is modulate