Zobrazeno 1 - 10
of 177
pro vyhledávání: '"Hinrich Schulenburg"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Caenorhabditis elegans is an appealing tool for experimental evolution and for working with antiparasitic drugs, from understanding the molecular mechanisms of drug action and resistance to uncover new drug targets. We present a new methodol
Externí odkaz:
https://doaj.org/article/f9fcff0429bf49bba79eda24baedfa82
Autor:
Leif Tueffers, Aditi Batra, Johannes Zimmermann, João Botelho, Florian Buchholz, Junqi Liao, Nicolás Mendoza Mejía, Antje Munder, Jens Klockgether, Burkhard Tüemmler, Jan Rupp, Hinrich Schulenburg
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 7 (2024)
ABSTRACT Pseudomonas aeruginosa is a ubiquitous, opportunistic human pathogen. Since it often expresses multidrug resistance, new treatment options are urgently required. Such new treatments are usually assessed with one of the canonical laboratory s
Externí odkaz:
https://doaj.org/article/03e4de67c9534611a14e37d744063dcb
Autor:
Johannes Zimmermann, Agnes Piecyk, Michael Sieber, Carola Petersen, Julia Johnke, Lucas Moitinho-Silva, Sven Künzel, Lena Bluhm, Arne Traulsen, Christoph Kaleta, Hinrich Schulenburg
Publikováno v:
mBio, Vol 15, Iss 5 (2024)
ABSTRACTThe microbiome expresses a variety of functions that influence host biology. The range of functions depends on the microbiome’s composition, which can change during the host’s lifetime due to neutral assembly processes, host-mediated sele
Externí odkaz:
https://doaj.org/article/f4bf6101c9d04ae79a39e76a8e7c9d6b
Autor:
Avril J. E. von Hoyningen-Huene, Corinna Bang, Philipp Rausch, Malte Rühlemann, Hanna Fokt, Jinru He, Nadin Jensen, Mirjam Knop, Carola Petersen, Lara Schmittmann, Thorsten Zimmer, John F. Baines, Thomas C. G. Bosch, Ute Hentschel, Thorsten B. H. Reusch, Thomas Roeder, Andre Franke, Hinrich Schulenburg, Eva Stukenbrock, Ruth A. Schmitz
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
Metaorganism research contributes substantially to our understanding of the interaction between microbes and their hosts, as well as their co-evolution. Most research is currently focused on the bacterial community, while archaea often remain at the
Externí odkaz:
https://doaj.org/article/0b601b86fb014f629756c622207bfb9f
Autor:
Georgios Marinos, Inga K. Hamerich, Reena Debray, Nancy Obeng, Carola Petersen, Jan Taubenheim, Johannes Zimmermann, Dana Blackburn, Buck S. Samuel, Katja Dierking, Andre Franke, Matthias Laudes, Silvio Waschina, Hinrich Schulenburg, Christoph Kaleta
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 2 (2024)
ABSTRACTWhile numerous health-beneficial interactions between host and microbiota have been identified, there is still a lack of targeted approaches for modulating these interactions. Thus, we here identify precision prebiotics that specifically modu
Externí odkaz:
https://doaj.org/article/dfd5fc11170342dbbd4f161ad4e7fab6
Autor:
João Botelho, Leif Tüffers, Janina Fuss, Florian Buchholz, Christian Utpatel, Jens Klockgether, Stefan Niemann, Burkhard Tümmler, Hinrich Schulenburg
Publikováno v:
EBioMedicine, Vol 90, Iss , Pp 104532- (2023)
Summary: Background: Pseudomonas aeruginosa is an opportunistic pathogen consisting of three phylogroups (hereafter named A, B, and C). Here, we assessed phylogroup-specific evolutionary dynamics across available and also new P. aeruginosa genomes. M
Externí odkaz:
https://doaj.org/article/4ede90c0a17f41b98e9f91e82f30bd84
Autor:
Kohar Annie B. Kissoyan, Lena Peters, Christoph Giez, Jan Michels, Barbara Pees, Inga K. Hamerich, Hinrich Schulenburg, Katja Dierking
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
The Caenorhabditis elegans natural microbiota was described only recently. Thus, our understanding of its effects on nematode physiology is still in its infancy. We previously showed that the C. elegans natural microbiota isolates Pseudomonas lurida
Externí odkaz:
https://doaj.org/article/204a27be92a841a0a9809cf73571657b
Autor:
Philipp Dirksen, Adrien Assié, Johannes Zimmermann, Fan Zhang, Adina-Malin Tietje, Sarah Arnaud Marsh, Marie-Anne Félix, Michael Shapira, Christoph Kaleta, Hinrich Schulenburg, Buck S. Samuel
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 10, Iss 9, Pp 3025-3039 (2020)
The study of microbiomes by sequencing has revealed a plethora of correlations between microbial community composition and various life-history characteristics of the corresponding host species. However, inferring causation from correlation is often
Externí odkaz:
https://doaj.org/article/fe2315f55dab4adaa9dd44d25a68c654
Publikováno v:
BMC Evolutionary Biology, Vol 20, Iss 1, Pp 1-14 (2020)
Abstract Background Red Queen dynamics are defined as long term co-evolutionary dynamics, often with oscillations of genotype abundances driven by fluctuating selection in host-parasite systems. Much of our current understanding of these dynamics is
Externí odkaz:
https://doaj.org/article/3dbb27279106469980e61e8ecf657462
Autor:
Basten L Snoek, Mark G Sterken, Harm Nijveen, Rita J M Volkers, Joost Riksen, Philip C Rosenstiel, Hinrich Schulenburg, Jan E Kammenga
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 11, Iss 10 (2021)
AbstractStudying genetic variation of gene expression provides a powerful way to unravel the molecular components underlying complex traits. Expression quantitative trait locus (eQTL) studies have been performed in several different model species, ye
Externí odkaz:
https://doaj.org/article/8a271855b44b44749eab8608377d268b