Zobrazeno 1 - 10 of 2 520 pro vyhledávání: '"Hinkle G."'
1
Akademický článek
High resistance barrier and prophylactic protection in preclinical models of SARS-CoV-2 with two siRNA combination.
Autor: Anglero-Rodriguez YI; Alnylam Pharmaceuticals; Cambridge, MA 002142, USA., Lempp FA; Vir Biotechnology Inc.; San Francisco, CA 94158, USA., Subramanian M; Alnylam Pharmaceuticals; Cambridge, MA 002142, USA., McIninch J; Alnylam Pharmaceuticals; Cambridge, MA 002142, USA., Schlegel MK; Alnylam Pharmaceuticals; Cambridge, MA 002142, USA., Bohan D; Vir Biotechnology Inc.; San Francisco, CA 94158, USA., Wong E; Vir Biotechnology Inc.; San Francisco, CA 94158, USA., Brown CR; Alnylam Pharmaceuticals; Cambridge, MA 002142, USA., Foster DJ; Alnylam Pharmaceuticals; Cambridge, MA 002142, USA., Castoreno AB; Alnylam Pharmaceuticals; Cambridge, MA 002142, USA., Nguyen T; Alnylam Pharmaceuticals; Cambridge, MA 002142, USA., Cuffe D; Alnylam Pharmaceuticals; Cambridge, MA 002142, USA., Montiel-Ruiz M; Vir Biotechnology Inc.; San Francisco, CA 94158, USA., Kaiser H; Vir Biotechnology Inc.; San Francisco, CA 94158, USA., Sahakyan A; Vir Biotechnology Inc.; San Francisco, CA 94158, USA., Spreafico R; Vir Biotechnology Inc.; San Francisco, CA 94158, USA., Morskaya SS; Alnylam Pharmaceuticals; Cambridge, MA 002142, USA., Barry JD; Alnylam Pharmaceuticals; Cambridge, MA 002142, USA., Berman D; Alnylam Pharmaceuticals; Cambridge, MA 002142, USA., Zhang L; Alnylam Pharmaceuticals; Cambridge, MA 002142, USA., Lefebvre S; Alnylam Pharmaceuticals; Cambridge, MA 002142, USA., Kasper A; Alnylam Pharmaceuticals; Cambridge, MA 002142, USA., Racie T; Alnylam Pharmaceuticals; Cambridge, MA 002142, USA., Weddle D; Alnylam Pharmaceuticals; Cambridge, MA 002142, USA., Mobley M; Alnylam Pharmaceuticals; Cambridge, MA 002142, USA., Wassarman K; Alnylam Pharmaceuticals; Cambridge, MA 002142, USA., Bisbe A; Alnylam Pharmaceuticals; Cambridge, MA 002142, USA., Zlatev I; Alnylam Pharmaceuticals; Cambridge, MA 002142, USA., Rogers A; Alnylam Pharmaceuticals; Cambridge, MA 002142, USA., Nechev L; Alnylam Pharmaceuticals; Cambridge, MA 002142, USA., Dybowski J; Alnylam Pharmaceuticals; Cambridge, MA 002142, USA., Chong S; Alnylam Pharmaceuticals; Cambridge, MA 002142, USA., Nair J; Alnylam Pharmaceuticals; Cambridge, MA 002142, USA., Simon A; Alnylam Pharmaceuticals; Cambridge, MA 002142, USA., Sloan K; Alnylam Pharmaceuticals; Cambridge, MA 002142, USA., Hwang S; Vir Biotechnology Inc.; San Francisco, CA 94158, USA., Virgin HW; Vir Biotechnology Inc.; San Francisco, CA 94158, USA.; Department of Pathology and Immunology, Washington University School of Medicine, Saint Louis, MO 63110, USA.; Department of Internal Medicine, UT Southwestern Medical Center, Dallas, TX 75390, USA., Fitzgerald K; Alnylam Pharmaceuticals; Cambridge, MA 002142, USA., Maier MA; Alnylam Pharmaceuticals; Cambridge, MA 002142, USA., Hinkle G; Alnylam Pharmaceuticals; Cambridge, MA 002142, USA., Hebner CM; Vir Biotechnology Inc.; San Francisco, CA 94158, USA., Akinc A; Alnylam Pharmaceuticals; Cambridge, MA 002142, USA., Jadhav V; Alnylam Pharmaceuticals; Cambridge, MA 002142, USA.
Publikováno v: Nucleic acids research [Nucleic Acids Res] 2024 Dec 09. Date of Electronic Publication: 2024 Dec 09.
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2
Akademický článek
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3
Akademický článek
Evaluation of RNAi therapeutics VIR-2218 and ALN-HBV for chronic hepatitis B: Results from randomized clinical trials.
Autor: Gane E; University of Auckland and New Zealand Clinical Research, Auckland, New Zealand. Electronic address: EdGane@adhb.govt.nz., Lim YS; Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea., Kim JB; Alnylam Pharmaceuticals, Cambridge, Massachusetts, USA., Jadhav V; Alnylam Pharmaceuticals, Cambridge, Massachusetts, USA., Shen L; Vir Biotechnology, Inc., San Francisco, California, USA., Bakardjiev AI; Vir Biotechnology, Inc., San Francisco, California, USA., Huang SA; Alnylam Pharmaceuticals, Cambridge, Massachusetts, USA., Cathcart AL; Vir Biotechnology, Inc., San Francisco, California, USA., Lempp FA; Vir Biotechnology, Inc., San Francisco, California, USA., Janas MM; Alnylam Pharmaceuticals, Cambridge, Massachusetts, USA., Cloutier DJ; Vir Biotechnology, Inc., San Francisco, California, USA., Kaittanis C; Alnylam Pharmaceuticals, Cambridge, Massachusetts, USA., Sepp-Lorenzino L; Alnylam Pharmaceuticals, Cambridge, Massachusetts, USA., Hinkle G; Alnylam Pharmaceuticals, Cambridge, Massachusetts, USA., Taubel J; Richmond Pharmacology Ltd., St George's University of London, London, UK., Haslett P; Alnylam Pharmaceuticals, Cambridge, Massachusetts, USA., Milstein S; Alnylam Pharmaceuticals, Cambridge, Massachusetts, USA., Anglero-Rodriguez YI; Alnylam Pharmaceuticals, Cambridge, Massachusetts, USA., Hebner CM; Vir Biotechnology, Inc., San Francisco, California, USA., Pang PS; Vir Biotechnology, Inc., San Francisco, California, USA., Yuen MF; Department of Medicine and State Key Laboratory of Liver Research, Queen Mary Hospital, The University of Hong Kong, Hong Kong, China.
Publikováno v: Journal of hepatology [J Hepatol] 2023 Oct; Vol. 79 (4), pp. 924-932. Date of Electronic Publication: 2023 Jun 07.
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5
Akademický článek
Low variation in ribosomal DNA and internal transcribed spacers of the symbiotic fungi of leaf-cutting ants (Attini: Formicidae)
Autor: Silva-Pinhati A.C.O., Bacci Jr. M., Hinkle G., Sogin M.L., Pagnocca F.C., Martins V.G., Bueno O.C., Hebling M.J.A.
Publikováno v: Brazilian Journal of Medical and Biological Research, Vol 37, Iss 10, Pp 1463-1472 (2004)
Leaf-cutting ants of the genera Atta and Acromyrmex (tribe Attini) are symbiotic with basidiomycete fungi of the genus Leucoagaricus (tribe Leucocoprineae), which they cultivate on vegetable matter inside their nests. We determined the variation of t
Externí odkaz: https://doaj.org/article/2a50cea69dc14f5e80e47ed56fc8fc0f
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6
Akademický článek
Rare loss of function variants in the hepatokine gene INHBE protect from abdominal obesity.
Autor: Deaton AM; Alnylam Pharmaceuticals, Cambridge, MA, USA. adeaton@alnylam.com., Dubey A; Alnylam Pharmaceuticals, Cambridge, MA, USA., Ward LD; Alnylam Pharmaceuticals, Cambridge, MA, USA., Dornbos P; Programs in Metabolism and Medical & Population Genetics, Broad Institute, Cambridge, MA, USA.; Division of Genetics and Genomics, Boston Children's Hospital, Boston, MA, USA.; Department of Pediatrics, Harvard Medical School, Boston, MA, USA., Flannick J; Programs in Metabolism and Medical & Population Genetics, Broad Institute, Cambridge, MA, USA.; Division of Genetics and Genomics, Boston Children's Hospital, Boston, MA, USA.; Department of Pediatrics, Harvard Medical School, Boston, MA, USA., Yee E; Alnylam Pharmaceuticals, Cambridge, MA, USA., Ticau S; Alnylam Pharmaceuticals, Cambridge, MA, USA., Noetzli L; Alnylam Pharmaceuticals, Cambridge, MA, USA., Parker MM; Alnylam Pharmaceuticals, Cambridge, MA, USA., Hoffing RA; Alnylam Pharmaceuticals, Cambridge, MA, USA., Willis C; Alnylam Pharmaceuticals, Cambridge, MA, USA., Plekan ME; Alnylam Pharmaceuticals, Cambridge, MA, USA., Holleman AM; Alnylam Pharmaceuticals, Cambridge, MA, USA., Hinkle G; Alnylam Pharmaceuticals, Cambridge, MA, USA., Fitzgerald K; Alnylam Pharmaceuticals, Cambridge, MA, USA., Vaishnaw AK; Alnylam Pharmaceuticals, Cambridge, MA, USA., Nioi P; Alnylam Pharmaceuticals, Cambridge, MA, USA.
Publikováno v: Nature communications [Nat Commun] 2022 Jul 27; Vol. 13 (1), pp. 4319. Date of Electronic Publication: 2022 Jul 27.
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7
Akademický článek
Rare coding variants in DNA damage repair genes associated with timing of natural menopause.
Autor: Ward LD; Alnylam Pharmaceuticals, Cambridge, MA 02142, USA., Parker MM; Alnylam Pharmaceuticals, Cambridge, MA 02142, USA., Deaton AM; Alnylam Pharmaceuticals, Cambridge, MA 02142, USA., Tu HC; Alnylam Pharmaceuticals, Cambridge, MA 02142, USA., Flynn-Carroll AO; Alnylam Pharmaceuticals, Cambridge, MA 02142, USA., Hinkle G; Alnylam Pharmaceuticals, Cambridge, MA 02142, USA., Nioi P; Alnylam Pharmaceuticals, Cambridge, MA 02142, USA.
Publikováno v: HGG advances [HGG Adv] 2021 Dec 22; Vol. 3 (2), pp. 100079. Date of Electronic Publication: 2021 Dec 22 (Print Publication: 2022).
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8
Akademický článek
Gene-level analysis of rare variants in 379,066 whole exome sequences identifies an association of GIGYF1 loss of function with type 2 diabetes.
Autor: Deaton AM; Alnylam Pharmaceuticals, Cambridge, MA, USA. adeaton@alnylam.com., Parker MM; Alnylam Pharmaceuticals, Cambridge, MA, USA., Ward LD; Alnylam Pharmaceuticals, Cambridge, MA, USA., Flynn-Carroll AO; Alnylam Pharmaceuticals, Cambridge, MA, USA., BonDurant L; Alnylam Pharmaceuticals, Cambridge, MA, USA., Hinkle G; Alnylam Pharmaceuticals, Cambridge, MA, USA., Akbari P; Regeneron Genetics Center, Regeneron Pharmaceuticals, Tarrytown, NY, USA., Lotta LA; Regeneron Genetics Center, Regeneron Pharmaceuticals, Tarrytown, NY, USA., Baras A; Regeneron Genetics Center, Regeneron Pharmaceuticals, Tarrytown, NY, USA., Nioi P; Alnylam Pharmaceuticals, Cambridge, MA, USA.
Publikováno v: Scientific reports [Sci Rep] 2021 Nov 03; Vol. 11 (1), pp. 21565. Date of Electronic Publication: 2021 Nov 03.
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9
Akademický článek
GWAS of serum ALT and AST reveals an association of SLC30A10 Thr95Ile with hypermanganesemia symptoms.
Autor: Ward LD; Alnylam Pharmaceuticals, Cambridge, MA, USA. lward@alnylam.com., Tu HC; Alnylam Pharmaceuticals, Cambridge, MA, USA., Quenneville CB; Alnylam Pharmaceuticals, Cambridge, MA, USA., Tsour S; Alnylam Pharmaceuticals, Cambridge, MA, USA., Flynn-Carroll AO; Alnylam Pharmaceuticals, Cambridge, MA, USA., Parker MM; Alnylam Pharmaceuticals, Cambridge, MA, USA., Deaton AM; Alnylam Pharmaceuticals, Cambridge, MA, USA., Haslett PAJ; Alnylam Pharmaceuticals, Cambridge, MA, USA., Lotta LA; Regeneron Genetics Center, Tarrytown, NY, USA., Verweij N; Regeneron Genetics Center, Tarrytown, NY, USA., Ferreira MAR; Regeneron Genetics Center, Tarrytown, NY, USA., Baras A; Regeneron Genetics Center, Tarrytown, NY, USA., Hinkle G; Alnylam Pharmaceuticals, Cambridge, MA, USA., Nioi P; Alnylam Pharmaceuticals, Cambridge, MA, USA.
Publikováno v: Nature communications [Nat Commun] 2021 Jul 27; Vol. 12 (1), pp. 4571. Date of Electronic Publication: 2021 Jul 27.
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10
Akademický článek
Advancing human genetics research and drug discovery through exome sequencing of the UK Biobank.
Autor: Szustakowski JD; Bristol Myers Squibb, Princeton, NJ, USA., Balasubramanian S; Regeneron Pharmaceuticals, Tarrytown, NY, USA., Kvikstad E; Bristol Myers Squibb, Princeton, NJ, USA., Khalid S; Regeneron Pharmaceuticals, Tarrytown, NY, USA., Bronson PG; Biogen, Cambridge, MA, USA., Sasson A; Bristol Myers Squibb, Princeton, NJ, USA., Wong E; Takeda California, San Diego, CA, USA., Liu D; Regeneron Pharmaceuticals, Tarrytown, NY, USA., Wade Davis J; Abbvie, North Chicago, IL, USA., Haefliger C; AstraZeneca Centre for Genomics Research, Discovery Sciences, BioPharmaceuticals R&D, Cambridge, UK., Katrina Loomis A; Pfizer, Cambridge, MA, USA., Mikkilineni R; Takeda California, San Diego, CA, USA., Noh HJ; Abbvie, North Chicago, IL, USA., Wadhawan S; Bristol Myers Squibb, Princeton, NJ, USA., Bai X; Regeneron Pharmaceuticals, Tarrytown, NY, USA., Hawes A; Regeneron Pharmaceuticals, Tarrytown, NY, USA., Krasheninina O; Regeneron Pharmaceuticals, Tarrytown, NY, USA., Ulloa R; Regeneron Pharmaceuticals, Tarrytown, NY, USA., Lopez AE; Regeneron Pharmaceuticals, Tarrytown, NY, USA., Smith EN; Takeda California, San Diego, CA, USA., Waring JF; Abbvie, North Chicago, IL, USA., Whelan CD; Biogen, Cambridge, MA, USA., Tsai EA; Biogen, Cambridge, MA, USA., Overton JD; Regeneron Pharmaceuticals, Tarrytown, NY, USA., Salerno WJ; Regeneron Pharmaceuticals, Tarrytown, NY, USA., Jacob H; Abbvie, North Chicago, IL, USA., Szalma S; Takeda California, San Diego, CA, USA., Runz H; Biogen, Cambridge, MA, USA., Hinkle G; Alnylam Pharmaceuticals, Cambridge, MA, USA., Nioi P; Alnylam Pharmaceuticals, Cambridge, MA, USA., Petrovski S; AstraZeneca Centre for Genomics Research, Discovery Sciences, BioPharmaceuticals R&D, Cambridge, UK., Miller MR; Pfizer, Cambridge, MA, USA., Baras A; Regeneron Pharmaceuticals, Tarrytown, NY, USA., Mitnaul LJ; Regeneron Pharmaceuticals, Tarrytown, NY, USA., Reid JG; Regeneron Pharmaceuticals, Tarrytown, NY, USA. jeffrey.reid@regeneron.com.
Publikováno v: Nature genetics [Nat Genet] 2021 Jul; Vol. 53 (7), pp. 942-948. Date of Electronic Publication: 2021 Jun 28.
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