T(1) independent, T(2) (*) corrected chemical shift based fat-water separation with multi-peak fat spectral modeling is an accurate and precise measure of hepatic steatosis.

Autor: Hines CD, Frydrychowicz A, Hamilton G, Tudorascu DL, Vigen KK, Yu H, McKenzie CA, Sirlin CB, Brittain JH, Reeder SB, Hines, Catherine D G, Frydrychowicz, Alex, Hamilton, Gavin, Tudorascu, Dana L, Vigen, Karl K, Yu, Huanzhou, McKenzie, Charles A, Sirlin, Claude B, Brittain, Jean H, Reeder, Scott B

Publikováno v: Journal of Magnetic Resonance Imaging; Apr2011, Vol. 33 Issue 4, p873-881, 9p

Sex-Dependent Synaptic Remodeling of the Somatosensory Cortex in Mice With Prenatal Methadone Exposure.

Autor: Grecco GG; Department of Pharmacology and Toxicology, School of Medicine, Indiana University, Indianapolis, IN, United States.; Medical Scientist Training Program, School of Medicine, Indiana University, Indianapolis, IN, United States., Huang JY; The Linda and Jack Gill Center for Biomolecular Sciences, Indiana University, Bloomington, IN, United States.; Program in Neuroscience and Department of Psychological and Brain Sciences, Indiana University, Bloomington, IN, United States., Muñoz B; Department of Pharmacology and Toxicology, School of Medicine, Indiana University, Indianapolis, IN, United States., Doud EH; Department of Biochemistry and Molecular Biology, School of Medicine, Indiana University, Indianapolis, IN, United States., Hines CD; The Linda and Jack Gill Center for Biomolecular Sciences, Indiana University, Bloomington, IN, United States., Gao Y; Department of Pharmacology and Toxicology, School of Medicine, Indiana University, Indianapolis, IN, United States., Rodriguez B; Department of Pharmacology and Toxicology, School of Medicine, Indiana University, Indianapolis, IN, United States., Mosley AL; Department of Biochemistry and Molecular Biology, School of Medicine, Indiana University, Indianapolis, IN, United States., Lu HC; The Linda and Jack Gill Center for Biomolecular Sciences, Indiana University, Bloomington, IN, United States.; Program in Neuroscience and Department of Psychological and Brain Sciences, Indiana University, Bloomington, IN, United States., Atwood BK; Department of Pharmacology and Toxicology, School of Medicine, Indiana University, Indianapolis, IN, United States.; Stark Neurosciences Research Institute, School of Medicine, Indiana University, Indianapolis, IN, United States.

Publikováno v: Advances in drug and alcohol research [Adv Drug Alcohol Res] 2022 Apr; Vol. 2. Date of Electronic Publication: 2022 Apr 25.

In Vivo Imaging in Pharmaceutical Development and Its Impact on the 3Rs.

Autor: Campbell BR; Barry R. Campbell is an Associate Principal Scientist in Translational Biomarkers at Merck Research Laboratories in Kenilworth, New Jersey. Dinko Gonzalez Trotter, PhD, is a Senior Director in Early Clinical Development at Regeneron Pharmaceuticals, Inc., in Tarrytown, New York. Catherine D. Hines, PhD is a Director in Translational Biomarkers at Merck Research Laboratories in West Point, Pennsylvania. Manishkumar Patel, PhD is a Principal Scientist in Translational Biomarkers at Merck Research Laboratories in West Point, Pennsylvania. Weisheng Zhang is a Senior Principal Scientist in Translational Biomarkers at Merck Research Laboratories in Boston, Massachusetts. Jeffrey L. Evelhoch, PhD, is Vice President of Translational Biomarkers at Merck Research Laboratories in West Point, Pennsylvania., Gonzalez Trotter D; Barry R. Campbell is an Associate Principal Scientist in Translational Biomarkers at Merck Research Laboratories in Kenilworth, New Jersey. Dinko Gonzalez Trotter, PhD, is a Senior Director in Early Clinical Development at Regeneron Pharmaceuticals, Inc., in Tarrytown, New York. Catherine D. Hines, PhD is a Director in Translational Biomarkers at Merck Research Laboratories in West Point, Pennsylvania. Manishkumar Patel, PhD is a Principal Scientist in Translational Biomarkers at Merck Research Laboratories in West Point, Pennsylvania. Weisheng Zhang is a Senior Principal Scientist in Translational Biomarkers at Merck Research Laboratories in Boston, Massachusetts. Jeffrey L. Evelhoch, PhD, is Vice President of Translational Biomarkers at Merck Research Laboratories in West Point, Pennsylvania., Hines CD; Barry R. Campbell is an Associate Principal Scientist in Translational Biomarkers at Merck Research Laboratories in Kenilworth, New Jersey. Dinko Gonzalez Trotter, PhD, is a Senior Director in Early Clinical Development at Regeneron Pharmaceuticals, Inc., in Tarrytown, New York. Catherine D. Hines, PhD is a Director in Translational Biomarkers at Merck Research Laboratories in West Point, Pennsylvania. Manishkumar Patel, PhD is a Principal Scientist in Translational Biomarkers at Merck Research Laboratories in West Point, Pennsylvania. Weisheng Zhang is a Senior Principal Scientist in Translational Biomarkers at Merck Research Laboratories in Boston, Massachusetts. Jeffrey L. Evelhoch, PhD, is Vice President of Translational Biomarkers at Merck Research Laboratories in West Point, Pennsylvania., Li W; Barry R. Campbell is an Associate Principal Scientist in Translational Biomarkers at Merck Research Laboratories in Kenilworth, New Jersey. Dinko Gonzalez Trotter, PhD, is a Senior Director in Early Clinical Development at Regeneron Pharmaceuticals, Inc., in Tarrytown, New York. Catherine D. Hines, PhD is a Director in Translational Biomarkers at Merck Research Laboratories in West Point, Pennsylvania. Manishkumar Patel, PhD is a Principal Scientist in Translational Biomarkers at Merck Research Laboratories in West Point, Pennsylvania. Weisheng Zhang is a Senior Principal Scientist in Translational Biomarkers at Merck Research Laboratories in Boston, Massachusetts. Jeffrey L. Evelhoch, PhD, is Vice President of Translational Biomarkers at Merck Research Laboratories in West Point, Pennsylvania., Patel M; Barry R. Campbell is an Associate Principal Scientist in Translational Biomarkers at Merck Research Laboratories in Kenilworth, New Jersey. Dinko Gonzalez Trotter, PhD, is a Senior Director in Early Clinical Development at Regeneron Pharmaceuticals, Inc., in Tarrytown, New York. Catherine D. Hines, PhD is a Director in Translational Biomarkers at Merck Research Laboratories in West Point, Pennsylvania. Manishkumar Patel, PhD is a Principal Scientist in Translational Biomarkers at Merck Research Laboratories in West Point, Pennsylvania. Weisheng Zhang is a Senior Principal Scientist in Translational Biomarkers at Merck Research Laboratories in Boston, Massachusetts. Jeffrey L. Evelhoch, PhD, is Vice President of Translational Biomarkers at Merck Research Laboratories in West Point, Pennsylvania., Zhang W; Barry R. Campbell is an Associate Principal Scientist in Translational Biomarkers at Merck Research Laboratories in Kenilworth, New Jersey. Dinko Gonzalez Trotter, PhD, is a Senior Director in Early Clinical Development at Regeneron Pharmaceuticals, Inc., in Tarrytown, New York. Catherine D. Hines, PhD is a Director in Translational Biomarkers at Merck Research Laboratories in West Point, Pennsylvania. Manishkumar Patel, PhD is a Principal Scientist in Translational Biomarkers at Merck Research Laboratories in West Point, Pennsylvania. Weisheng Zhang is a Senior Principal Scientist in Translational Biomarkers at Merck Research Laboratories in Boston, Massachusetts. Jeffrey L. Evelhoch, PhD, is Vice President of Translational Biomarkers at Merck Research Laboratories in West Point, Pennsylvania., Evelhoch JL; Barry R. Campbell is an Associate Principal Scientist in Translational Biomarkers at Merck Research Laboratories in Kenilworth, New Jersey. Dinko Gonzalez Trotter, PhD, is a Senior Director in Early Clinical Development at Regeneron Pharmaceuticals, Inc., in Tarrytown, New York. Catherine D. Hines, PhD is a Director in Translational Biomarkers at Merck Research Laboratories in West Point, Pennsylvania. Manishkumar Patel, PhD is a Principal Scientist in Translational Biomarkers at Merck Research Laboratories in West Point, Pennsylvania. Weisheng Zhang is a Senior Principal Scientist in Translational Biomarkers at Merck Research Laboratories in Boston, Massachusetts. Jeffrey L. Evelhoch, PhD, is Vice President of Translational Biomarkers at Merck Research Laboratories in West Point, Pennsylvania.

Publikováno v: ILAR journal [ILAR J] 2016 Dec; Vol. 57 (2), pp. 212-220.

MRI as a Novel In Vivo Approach for Assessing Structural Changes of Chlamydia Pathology in a Mouse Model.

Autor: Hines CD; Department of Translational Imaging Biomarkers, MRL (West Point, PA), Merck & Co., Inc., Kenilworth, New Jersey, United States of America., Wang S; Department of Biometrics Research, MRL (Rahway, NJ), Merck & Co., Inc., Kenilworth, New Jersey, United States of America., Meng X; Department of Translational Imaging Biomarkers, MRL (West Point, PA), Merck & Co., Inc., Kenilworth, New Jersey, United States of America., Skinner JM; Department of Vaccines Early Discovery, MRL (West Point, PA), Merck & Co., Inc., Kenilworth, New Jersey, United States of America., Heinrichs JH; Global Project Leadership, Sanofi Pasteur, Swiftwater, Pennsylvania, United States of America., Smith JG; Pharmaceutical Sciences Analytical Research & Development, Pfizer, Andover, Massachusetts, United States of America., Boddicker MA; Department of Vaccines Early Discovery, MRL (West Point, PA), Merck & Co., Inc., Kenilworth, New Jersey, United States of America.

Publikováno v: PloS one [PLoS One] 2016 Jul 28; Vol. 11 (7), pp. e0160055. Date of Electronic Publication: 2016 Jul 28 (Print Publication: 2016).

Adipose tissue MRI for quantitative measurement of central obesity.

Autor: Poonawalla AH; Department of Radiology, University of Wisconsin, Madison, Wisconsin 53792-3252, USA., Sjoberg BP, Rehm JL, Hernando D, Hines CD, Irarrazaval P, Reeder SB

Publikováno v: Journal of magnetic resonance imaging : JMRI [J Magn Reson Imaging] 2013 Mar; Vol. 37 (3), pp. 707-16. Date of Electronic Publication: 2012 Oct 10.