Coupling of gene expression in medial prefrontal cortex and nucleus accumbens after neonatal ventral hippocampal lesions accompanies deficits in sensorimotor gating and auditory processing in rats

Autor: Swerdlow, Neal R., Powell, Susan B., Breier, Michelle R., Hines, Samantha R., Light, Gregory A.

Publikováno v: In Neuropharmacology December 2013 75:38-46

Opposite effects of tolcapone on amphetamine-disrupted startle gating in low vs. high COMT-expressing rat strains

Autor: Swerdlow, Neal R., Hines, Samantha R., Herrera, Sebastian D., Weber, Martin, Breier, Michelle R.

Publikováno v: In Pharmacology, Biochemistry and Behavior May 2013 106:128-131

Forebrain gene expression predicts deficits in sensorimotor gating after isolation rearing in male rats

Autor: Swerdlow, Neal R, Light, Gregory A, Trim, Ryan S, Breier, Michelle R, Hines, Samantha R, Powell, Susan B

Publikováno v: Swerdlow, NR; Light, GA; Trim, RS; Breier, MR; Hines, SR; & Powell, SB. (2013). Forebrain gene expression predicts deficits in sensorimotor gating after isolation rearing in male rats. Behavioural Brain Research, 257, 118-128. doi: 10.1016/j.bbr.2013.09.005. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/3b84p67b

Compared to socially housed (SH) rats, adult isolation-reared (IR) rats exhibit phenotypes relevant to schizophrenia (SZ), including reduced prepulse inhibition (PPI) of startle. PPI is normally regulated by the medial prefrontal cortex (mPFC) and nu

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http://www.escholarship.org/uc/item/3b84p67b