Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Hindol Gupta"'
Autor:
Geethu E. Thomas, K. Bandopadhyay, Sabyasachi Sutradhar, M. R. Renjith, Puja Singh, K. K. Gireesh, Steny Simon, Binshad Badarudeen, Hindol Gupta, Manidipa Banerjee, Raja Paul, J. Mitra, Tapas K. Manna
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
Ska1 is a kinetochore-localised protein that couples kinetochore movement to microtubule (MT) depolymerisation. Here Thomas et al. show that the MT +TIP binding protein EB1 recruits Ska1 to the MT-kinetochore interface and stabilises the interaction
Externí odkaz:
https://doaj.org/article/f53440769de3492a93c9e28514a15bd5
Autor:
Alexander E. Kelly, Mary Kate Bonner, Hayden Saunders, Julian Haase, Hindol Gupta, Biyun Iris Li
Publikováno v:
Molecular Biology of the Cell
The chromosomal passenger complex (CPC), which includes the kinase Aurora B, is a master regulator of meiotic and mitotic processes that ensure the equal segregation of chromosomes. Sgo1 is thought to play a major role in the recruitment of the CPC t
Autor:
Hindol Gupta, Manidipa Banerjee, K. Bandopadhyay, J. Mitra, Puja Singh, Geethu Emily Thomas, Steny Simon, Raja Paul, Sabyasachi Sutradhar, Tapas Manna, Binshad Badarudeen, M. R. Renjith, K. K. Gireesh
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
Nature Communications
Nature Communications
Kinetochore couples chromosome movement to dynamic microtubules, a process that is fundamental to mitosis in all eukaryotes but poorly understood. In vertebrates, spindle-kinetochore-associated (Ska1–3) protein complex plays an important role in th
Autor:
Sarit S. Agasti, Tapas Manna, Ranjan Sasmal, Nurni R. Aparna, Hindol Gupta, Ushma Anand, Renjith M. Radhakrishnan, Resmi Rajeev, Haritha Chandran
Publikováno v:
Current biology : CB. 30(12)
Summary Centrioles are essential components of centrosome, the main microtubule-organizing center of animal cells required for robust spindle bipolarity [ 1 , 2 ]. They are duplicated once during the cell cycle [ 3 ], and the duplication involves ass
Autor:
Tapas Manna, Hindol Gupta, Athira George, Binshad Badarudeen, Geethu Emily Thomas, K. K. Gireesh
Publikováno v:
Biochemistry. 54:6413-6422
Centrioles are essential components of the animal centrosome and play crucial roles in the formation of cilia and flagella. They are cylindrical structures composed of nine triplet microtubules organized around a central cartwheel. Recent studies hav
Autor:
Tapas Manna, Soumyananda Chakraborti, Hindol Gupta, Puja Singh, K. K. Gireesh, Jamuna S. Sreeja, Geethu Emily Thomas
Publikováno v:
Biochemistry. 53(34)
The +TIP protein EB1 autonomously tracks the growing plus end of microtubules and regulates plus-end dynamics. Previous studies have indicated that EB1 can recognize GTP-bound tubulin structures at the plus end, and it localizes on the microtubule su
Publikováno v:
International journal of oncology. 46(1)
Microtubule plus‑end‑binding protein (+TIP) EB1 has been shown to be upregulated in breast cancer cells and promote breast tumor growth in vivo. However, its effect on the cellular actions of microtubule‑targeted drugs in breast cancer cells ha