Zobrazeno 1 - 10
of 818
pro vyhledávání: '"Hindlimb-unloading"'
Publikováno v:
Immunity & Ageing, Vol 21, Iss 1, Pp 1-20 (2024)
Abstract Spaceflight poses a myriad of environmental stressors to astronauts´ physiology including microgravity and radiation. The individual impacts of microgravity and radiation on the immune system have been extensively investigated, though a com
Externí odkaz:
https://doaj.org/article/7f6f376640f54ed9977c863e2ba84ca4
Autor:
Jin-Man Kim, Ho Kyoung Kim, Han Jin Cho, Sung-Ah Moon, Yewon Kim, Jeong Yeon Hong, Seung Hun Lee, Kyunggon Kim, Jung-Min Koh
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-17 (2024)
Abstract Aging and lack of exercise are the most important etiological factors for muscle loss. We hypothesized that new factors that contribute to muscle loss could be identified from ones commonly altered in expression in aged and exercise-limited
Externí odkaz:
https://doaj.org/article/2a97c593a1584ff0a73b520c231c58bc
Autor:
Jacob Raber, Mitali Chaudhari, Alexis De la Torre, Sarah Holden, Kat Kessler, Breanna Glaeser, Marek Lenarczyk, Scott Willem Leonard, Alexander Borg, Andy Kwok, Chirayu Patel, Amy Kronenberg, Christopher M. Olsen, Jeffrey S. Willey, Jeffrey Morré, Jaewoo Choi, Jan Frederik Stevens, Gerd Bobe, Jessica Minnier, John Baker
Publikováno v:
Frontiers in Physiology, Vol 15 (2024)
IntroductionEffects and interactions between different spaceflight stressors are expected to be experienced by crew on missions when exposed to microgravity and galactic cosmic rays (GCRs). One of the limitations of previous studies on simulated weig
Externí odkaz:
https://doaj.org/article/2dec1e3601ec4a3796d0c67f4ecd7326
Publikováno v:
Jichu yixue yu linchuang, Vol 44, Iss 6, Pp 772-778 (2024)
Objective To explore the protective effects and the underlying mechanisms of bone marrow mesenchymal stem cells (BMSCs) on the brain in microgravity environment. Methods The physiological effects of microgravity were simulated with the hindlimb unloa
Externí odkaz:
https://doaj.org/article/7a6151fd63d8461fbb8df37efdb59cf5
Publikováno v:
BMC Musculoskeletal Disorders, Vol 24, Iss 1, Pp 1-10 (2023)
Abstract Introduction The purpose of this study was to evaluate the protective effects of cordymin on osteoporosis induced by hindlimb unloading(HLU) in rats and whether cordymin can prevent bone loss from HLU. Materials and methods We employed the h
Externí odkaz:
https://doaj.org/article/381fb4d9fac8497dafb7f830dff98eff
Autor:
Tian Liu, Yuqi Ma, Hui Zhao, Pengli Wang, Yan Niu, Yuehuan Hu, Xi Shen, Mingxia Zhang, Bing Yan, Jun Yu
Publikováno v:
Pharmaceutical Biology, Vol 61, Iss 1, Pp 683-695 (2023)
AbstractContext Hawthorn leaves are a kind of widely used medicinal plant in China. The major ingredient, hawthorn leaves flavonoids (HLF), have cardiotonic, cardioprotective, and vascular protective effects.Objective The study evaluated the protecti
Externí odkaz:
https://doaj.org/article/295ef4e9107a42a782e39ae7a5326660
Autor:
Jacob Raber, Sarah Holden, Kat Kessler, Breanna Glaeser, Chloe McQuesten, Mitali Chaudhari, Fiona Stenzel, Marek Lenarczyk, Scott Willem Leonard, Jeffrey Morré, Jaewoo Choi, Amy Kronenberg, Alexander Borg, Andy Kwok, Jan Frederik Stevens, Christopher Olsen, Jeffrey S. Willey, Gerd Bobe, Jessica Minnier, John E. Baker
Publikováno v:
Frontiers in Physiology, Vol 14 (2024)
Introduction: The space environment astronauts experience during space missions consists of multiple environmental challenges, including microgravity. In this study, we assessed the behavioral and cognitive performances of male Fisher rats 2 months a
Externí odkaz:
https://doaj.org/article/1bb6f8739e9d45ff9ac8c715fc29053f
Autor:
Zeinab Ibrahim, Naveed A. Khan, Rizwan Qaisar, Mohamed A. Saleh, Ruqaiyyah Siddiqui, Hamza M. Al-Hroub, Alexander D. Giddey, Mohammad Harb Semreen, Nelson C. Soares, Adel B. Elmoselhi
Publikováno v:
Heliyon, Vol 10, Iss 1, Pp e23592- (2024)
Microgravity, in space travel and prolonged bed rest conditions, induces cardiovascular deconditioning along with skeletal muscle mass loss and weakness. The findings of microgravity research may also aid in the understanding and treatment of human h
Externí odkaz:
https://doaj.org/article/558b500fc0af4040bc637c6b544bf629
Autor:
Kristina A. Sharlo, Irina D. Lvova, Sergey A. Tyganov, Ksenia V. Sergeeva, Vitaly Y. Kalashnikov, Ekaterina P. Kalashnikova, Timur M. Mirzoev, Grigoriy R. Kalamkarov, Tatiana F. Shevchenko, Boris S. Shenkman
Publikováno v:
Current Issues in Molecular Biology, Vol 45, Iss 7, Pp 5613-5630 (2023)
Skeletal muscle disuse leads to pathological muscle activity as well as to slow-to-fast fiber-type transformation. Fast-type fibers are more fatigable than slow-type, so this transformation leads to a decline in muscle function. Prochlorperazine inje
Externí odkaz:
https://doaj.org/article/7c81d0e0556646f9bd2e1b8fbd1b2b27
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