Cell-specific alterations in Pitx1 regulatory landscape activation caused by the loss of a single enhancer

Autor: Raquel Rouco, Olimpia Bompadre, Antonella Rauseo, Olivier Fazio, Rodrigue Peraldi, Fabrizio Thorel, Guillaume Andrey

Publikováno v: Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Nature communications, Vol. 12, No 1 (2021) P. 7235

Developmental genes are frequently controlled by multiple enhancers sharing similar specificities. As a result, deletions of such regulatory elements have often failed to reveal their full function. Here, we use the Pitx1 testbed locus to characteriz

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37b5a53a17c83d09b92f2147f4291ae1
http://europepmc.org/articles/PMC8668926