Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Hindbrain formation"'
Autor:
Houda Kilani, Aljazi Al-Maraghi, Sahar I. Da'as, Alya Al-Kurbi, Waleed Aamer, Khalid A. Fakhro, Mitchell A. Stotland, Khaled Zamel, Jehan AlRayahi, Waseem Hasan
Publikováno v:
Cells
Volume 9
Issue 8
Cells, Vol 9, Iss 1782, p 1782 (2020)
Volume 9
Issue 8
Cells, Vol 9, Iss 1782, p 1782 (2020)
Recessive mutations in Post-GPI attachment to proteins 3 (PGAP3) cause the rare neurological disorder hyperphosphatasia with mental retardation syndrome 4 type (HPMRS4). Here, we report a novel homozygous nonsense mutation in PGAP3 (c.265C>
T-
T-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb0860475c8eb5320407fa2bcd2ad6b8
Publikováno v:
The International Journal of Developmental Biology. 62:767-774
Hox proteins have long been known to function as transcriptional regulators during development of the vertebrate hindbrain. In particular, these factors are thought to play key roles in assigning distinct fates to the rhombomere segments arising in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec61e3eb010edc4b4108d866b8694a4e
https://doi.org/10.1387/ijdb.180141cs
https://doi.org/10.1387/ijdb.180141cs
Publikováno v:
World neurosurgery. 135
Background Chiari malformations include a large spectrum of anomalies of hindbrain formation that appear at different stages of development of the central nervous system. Chiari described these malformations as congenital anomalies of the hindbrain c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ac73650431a6aebdb8b4e0c8a0ce537
https://pubmed.ncbi.nlm.nih.gov/31704358
https://pubmed.ncbi.nlm.nih.gov/31704358
Publikováno v:
Neural Development
Neural Development, Vol 13, Iss 1, Pp 1-24 (2018)
Neural Development, Vol 13, Iss 1, Pp 1-24 (2018)
Background Previous work aimed at understanding the gene regulatory networks (GRNs) governing caudal hindbrain formation identified morphogens such as Retinoic Acid (RA) and Fibroblast growth factors (FGFs), as well as transcription factors like hoxb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af4e63df488fd32457e6a50161ef4d4f
https://doi.org/10.1186/s13064-018-0112-y
https://doi.org/10.1186/s13064-018-0112-y
Autor:
Ronald D. G. McKay, Ioannis Karampelas, Marannia Saridaki, Nikolaos Mandalos, Eumorphia Remboutsika, Mark L. Cohen
The cerebellum, a derivative of the hindbrain, plays a crucial role in balance and posture as well as in higher cognitive and locomotive processes. Cerebellar development is initiated during the segmental phase of hindbrain formation. Here, we descri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1534dfd520cf8b3d774aff65fc4fb947
https://europepmc.org/articles/PMC6295446/
https://europepmc.org/articles/PMC6295446/
Autor:
Satoshi Shimozono, Shin-ichi Higashijima, Atsushi Miyawaki, Tadahiro Iimura, Tetsuya Kitaguchi
Publikováno v:
Nature. 496:363-366
In vertebrate development, the body plan is determined by primordial morphogen gradients that suffuse the embryo. Retinoic acid (RA) is an important morphogen involved in patterning the anterior-posterior axis of structures, including the hindbrain a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b15ffe5f3986c2518d6509c59cdecb22
https://doi.org/10.1038/nature12037
https://doi.org/10.1038/nature12037
Autor:
Yuval Ebenstein, Deepak Kumar Sinha, Carole Gauron, Zhiping Feng, Arbel D. Tadmor, David Bensimon, Shuo Lin, Sophie Vriz, Bertrand Ducos, Lijun Xu, Thomas Le Saux, Shimon Weiss, Ludovic Jullien
Publikováno v:
Development. 139:3355-3362
All-trans retinoic acid (RA) is a key player in many developmental pathways. Most methods used to study its effects in development involve continuous all-trans RA activation by incubation in a solution of all-trans RA or by implanting all-trans RA-so
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42075c148608d34d6cb15aa1eb9c7f7d
https://doi.org/10.1242/dev.077776
https://doi.org/10.1242/dev.077776
Autor:
Ori Scott, Helly Goez
Publikováno v:
Journal of Child Neurology. 26:1311-1315
Studies in animal models have established that intra-uterine vitamin A deficiency can hinder hindbrain formation; however, reports of such a phenomenon in humans had not been published until recently, when our group presented the case of an infant di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3a3c575fd04d4bad6ff959ef1443852
https://doi.org/10.1177/0883073811402202
https://doi.org/10.1177/0883073811402202
Autor:
Hiroyuki Takeda, Kyo Yamasu, Yuri Kuroyanagi, Akiko Ishioka, Tomoko Jindo, Mst. Shahnaj Parvin, Toshihiro Kawanabe, Masataka Nikaido, Kohei Hatta
Publikováno v:
Developmental Biology. 350:154-168
Zebrafish hoxb1b is expressed during epiboly in the posterior neural plate, with its anterior boundary at the prospective r4 region providing a positional cue for hindbrain formation. A similar function and expression is known for Hoxa1 in mice, sugg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4825f24661501967af8aa71a5c522f59
https://doi.org/10.1016/j.ydbio.2010.10.011
https://doi.org/10.1016/j.ydbio.2010.10.011
Autor:
Yoni E. Gutkovich, Rachel Ofir, Charna Dibner, Dale Frank, Yaniv M. Elkouby, Aharon Gefen, Sarah Elias
Publikováno v:
Developmental Biology, Vol. 338, No 1 (2010) pp. 50-62
In Xenopus embryos, XMeis3 protein activity is required for normal hindbrain formation. Our results show that XMeis3 protein knock down also causes a loss of primary neuron and neural crest cell lineages, without altering expression of Zic, Sox or Pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a21cf9ff0c87740f6ab906476b7ee422
https://doi.org/10.1016/j.ydbio.2009.11.024
https://doi.org/10.1016/j.ydbio.2009.11.024