Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Hinda Bergman"'
Publikováno v:
Toxicology and Applied Pharmacology. 32:461-473
Aroclor 1242 and Aroclor 1016 are polychlorinated biphenyl (PCB) mixtures with similar chlorine content (42 vs 41%), but Aroclor 1242 contains 9% biphenyl homologs with five or more chlorines while Aroclor 1016 contains only 1%. The effects of Aroclo
Autor:
R. McGaughy, Verne A. Ray, Hinda Bergman, M. Argus, K. Chu, C. Frith, Thomas J. Slaga, Raymond W. Tennant, Stephen Nesnow, E. Weisburger, T. Helmes
Publikováno v:
Mutation Research/Reviews in Genetic Toxicology. 185:1-195
The literature on 506 selected chemicals has been evaluated for evidence that these chemicals induce tumors in experimental animals and this assessment comprises the Gene-Tox Carcinogen Data Base. Three major sources of information were used to creat
Autor:
Marlin D. Friesen, Patricia Hickman, Joyce A. Goldstein, J. Ronald Hass, Ralph E. Linder, Hinda Bergman
Publikováno v:
Biochemical Pharmacology. 26:1549-1557
The hepatic effects of technical and pure grade pentachlorophenol were investigated in female rats fed 20, 100 and 500 ppm of each for 8 months. Technical pentachlorophenol was contaminated with 8 ppm hexa-, 520 ppm hepta-, and 1380 ppm octachlorodib
Autor:
Stephen Nesnow, Hinda Bergman
Publikováno v:
Life Sciences. 25:2099-2104
1,2-Naphthoquinone can function as an electron transport component in the non-enzymic oxidation of benzo(a)pyrene [B(a)P]. With reducing equivalents supplied by NADPH, the reaction is proportional to time and the increasing concentrations of 1,2-naph
Toxicological assessment of hexachlorobiphenyl isomers and 2,3,7,8-tetrachlorodibenzofuran in chicks
Autor:
J.A. Moore, Patricia Hickman, George W. Lucier, Hinda Bergman, Joyce A. Goldstein, James D. McKinney
Publikováno v:
Toxicology and Applied Pharmacology. 36:81-92
Pure hexachlorobiphenyl (HCB) isomers induce a number of changes in parameters of drug metabolism in the chick including changes in cytochrome P-450, liver weight, and p-nitrophenol glucuronyl transferase, but not in testosterone glucuronyl transfera
Autor:
Stephen Nesnow, Hinda Bergman
Publikováno v:
Mutation Research/Genetic Toxicology. 205:237-253
The Gene-Tox Carcinogen Data Base is an evaluated source of cancer data on 506 chemicals selected in part for their previous assessment in genetic toxicology bioassays. This data base has been analyzed for the distribution of these chemicals into che
Publikováno v:
Journal of Toxicology and Environmental Health. 24:499-513
A group of 36 aryl azo dyes were examined for their ability to be reduced by rat liver microsomal azoreductase. This group of azo dyes featured a variety of substituents, including sulfonic acid, phenol, nitro, amide, and methyl functionalities on ph
Publikováno v:
Toxicology Letters. 14:7-13
alpha-Naphthoflavone (ANF) inhibits beta-naphthoflavone-induced rat liver microsomal benzo(a)pyrene metabolism and is transformed by these microsomes into alpha-naphthoflavone metabolites. We determined the inhibitory effect on benzo(a)pyrene (B(a)P)
Publikováno v:
Chemico-biological interactions. 17(1)
A number of isomerically pure polychlorinated biphenyls (PCBs) were tested as inducers of hepatic drug-metabolizing enzymes in the rat. The chlorinated biphenyl isomers can be categorized into two distinct groups of inducers, while commercial PCB mix
Autor:
Hinda Bergman, Warren L. Campbell, Stephen Nesnow, David L. Greenman, Robert L. Morrissey, Richard R. Allen, Charles H. Frith, Dean W. Roberts, George L. Wolff
Publikováno v:
Carcinogenesis. 8(12)
Obese mottled yellow Avy/a, lean pseudoagouti Avy/a and lean black a/a (YS X VY) F-1 hybrid female mice were fed diet containing 160 p.p.m. lindane (gamma-hexachlorocyclohexane) for 6, 12, 18 or 24 months. Clara cell hyperplasia was present in a majo