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of 3
pro vyhledávání: '"Hinal Tanna"'
Autor:
David G Kent, Juan Li, Hinal Tanna, Juergen Fink, Kristina Kirschner, Dean C Pask, Yvonne Silber, Tina L Hamilton, Rachel Sneade, Benjamin D Simons, Anthony R Green
Publikováno v:
PLoS Biology, Vol 11, Iss 6, p e1001576 (2013)
Recent descriptions of significant heterogeneity in normal stem cells and cancers have altered our understanding of tumorigenesis, emphasizing the need to understand how single stem cells are subverted to cause tumors. Human myeloproliferative neopla
Externí odkaz:
https://doaj.org/article/7dfd3a5ed19c436ab9d0cf6c7ee2e024
Autor:
Roberto Bandiera, Martyna C. Popis, Michaela Frye, Abdulrahim A. Sajini, Sandra Blanco, Nikoletta A. Gkatza, Hinal Tanna, Rosana Cortés-Garrido, Sabine Dietmann, Jelena Aleksic, Patrick Lombard, Shobbir Hussain
Publikováno v:
Nature
Whether protein synthesis and cellular stress response pathways interact to control stem cell function is currently unknown. Here we show that mouse skin stem cells synthesize less protein than their immediate progenitors in vivo, even when forced to
Autor:
Hinal Tanna, Dean C. Pask, Benjamin D. Simons, Juergen Fink, Kristina Kirschner, Yvonne Silber, Rachel Sneade, Tina L. Hamilton, David G. Kent, Anthony R. Green, Juan Li
Publikováno v:
PLoS Biology
PLoS Biology, Vol 11, Iss 6, p e1001576 (2013)
PLoS Biology, Vol 11, Iss 6, p e1001576 (2013)
In this study, single cell assays and mathematical modeling demonstrate that a single oncogenic point mutation can negatively affect hematopoietic stem cells while leaving progenitor cell expansion intact.
Recent descriptions of significant hete
Recent descriptions of significant hete