Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Hinaho Suginoma"'
Autor:
Ayaka Mori, Taichi Shiroishi, Jun Fujioka, Takashi Nakajima, Shinichi Mitsui, Hinaho Suginoma, Yohei Kakuta, Heishun Zen, Kazuhiro Nakamura
Publikováno v:
Brain Disorders, Vol 14, Iss , Pp 100137- (2024)
Polyglutamine (polyQ) diseases are devastating neurological disorders that cannot be effectively treated. Repeat-associated non-AUG (RAN) translation has been documented in transcripts in polyQ diseases. RAN products include proteins with polyleucine
Externí odkaz:
https://doaj.org/article/32edc9fcff4845b0a59e4b09fc69181b
Publikováno v:
PLoS ONE, Vol 19, Iss 1, p e0296750 (2024)
Whether fibril formation increases or decreases cytotoxicity remains unclear. Aggregation of human islet amyloid polypeptide (hIAPP), a pivotal regulator of glucose homeostasis, impairs the function and viability of pancreatic β cells. Evidence sugg
Externí odkaz:
https://doaj.org/article/8159ac3aaa224a3fa4e372cacee00dba