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Akademický článek

Association of GSTM1 and GSTT1 genes insertion/deletion polymorphism with colorectal cancer risk: a case-control study of Khyber Pakhtunkhwa population Pakistan

Autor: Hina Zubair, Javeria Aurangzeb, Bushra Zubair, Muhammad Imran

Publikováno v: Journal of the Pakistan Medical Association, Vol 72, Iss 3 (2022)

Objective: To evaluate the genetic association of glutathione S transferase M1 and glutathione S transferase T1 genes insertion/deletion polymorphism with the risk of colorectal cancer. Method: This case-control study was conducted March 2018 and N

Externí odkaz: https://doaj.org/article/0c2b3f0d39444244a6af105236ea06af

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Efficacy and safety of antibody-drug conjugates in triple-negative and HER-2 positive breast cancer: A systematic review and meta-analysis of clinical trials

Autor: Fatima Afzal, Wajeeha Aiman, Hafsa Zahoor, Ayfa Riaz Bajwa, Syeda Hafsa Kazmi, Aqsa Anwar, Muhammad Yasir Anwar, Sana Rashid, Hina Zubair, Tooba Kashif, Muhammad Ashar Ali

Publikováno v: Breast Disease. 42:121-136

Breast cancer (BC) is the 2nd most common cause of cancer-related deaths. Antibody-drug conjugates (ADCs) are monoclonal antibodies linked to cytotoxic agents and are directed towards a specific tumor protein. Therefore, they are more potent and can

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::178e46265afc527b1b772fc9379ce4e2
https://doi.org/10.3233/bd-220052

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Impact of AKT1 polymorphism on DNA damage, BTG2 expression, and risk of colorectal cancer development

Autor: Hina Zubair, Zahid Khan, Muhammad Imran

Publikováno v: Radiology and Oncology. 56:336-345

Background AKT, also called protein kinase B, is a serine-threonine kinase that functions as a mediator of PI3K-Akt-mTOR signaling pathway and plays an important role in an array of cellular processes. Many single nucleotide polymorphisms (SNP) in AK

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9bc32fd53c15d587069245ff7e86ff73
https://doi.org/10.2478/raon-2022-0031

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Factors Associated with Early and Late Initiation of Antiretroviral Therapy among People Living with Human Immunodeficiency Virus in Lahore, Pakistan

Autor: Khunsa Junaid, Saad Muzaffar, Rabia Nazim, Amber Arshad, Amjad Khan, Hina Zubair

Publikováno v: Annals of King Edward Medical University. 28:39-45

Background: Despite the availability of antiretroviral therapy (ART), HIV is still responsible for substantial illness and death, especially in developing countries. Early start of treatment (ART) is associated with better therapeutic outcome, reduce

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0dd274e38b42fdd9352937e67792b067
https://doi.org/10.21649/akemu.v28i1.5014

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A Comparative Study of Ephedrine and Phenylephrine in Averting Hypotension during Cesarean Section under Spinal Anesthesia

Autor: Shahid Adalat Chaudhry, Mubashar Iqbal, Muhammad Nadeem Khan, Aurooj Fatima, Hina Zubair, Madiha Haroon

Publikováno v: Pakistan Journal of Medical and Health Sciences. 16:967-970

Maternal haemodynamic variations are communal during caesarean section by spinal anesthesia. Several measures are adopted to treat hypotension. The aim of this study is to compare the effectiveness of phenylephrine and ephedrine in treating and preve

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9e3955f43f1542d9cf103cb9a043b3a2
https://doi.org/10.53350/pjmhs22161967

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Comparison of Hemodynamic Changes after Use of Intrathecal 0.75% Hyperbaric Bupivacaine Versus 0.5% Hyperbaric Bupivacaine with Dexmeditomidine in Patients Undergoing Cesarean Section

Autor: Muhammad Nadeem Khan, Hina Zubair, Noreen Rasul, Saima Parveen, Aurooj Fatima, Shahid Adalt

Publikováno v: Pakistan Journal of Medical and Health Sciences. 16:346-348

Objective: To compare analysis of hemodynamic changes after use of intrathecal 0.75% and 0.5% hyperbaric bupivacaine with dexmedetomidine in cesarean section patients. Study Design: Comparative analytical study Place and Duration of Study: Divisional

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0960a8282e68aa229cb6e64a06902de3
https://doi.org/10.53350/pjmhs22166346

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A Comparative Study on the Effects of Spinal Versus General Anaesthesia on Apgar Score of the Neonates among Patients Enduring Elective Caesarean Section

Autor: Muhammad Nadeem Khan, Hina Zubair, Sara Akram, Saima Perveen, Arooj Fatima, Madiah .

Publikováno v: Pakistan Journal of Medical and Health Sciences. 16:526-528

Objective: The purpose of this analysis was to do the comparison of the effect of general anesthesia and spinal anesthesia on neonatal Apgar score in patients enduring elective cesarean section. Study design: A Randomized control trial. Place and dur

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::daf34e0cb0967cbd8eba16f103b10041
https://doi.org/10.53350/pjmhs22164526

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Effect of Amino Acids Infusion on Maternal and Perinatal Outcome in 3rd Trimester Idiopathic Oligohydramnios

Autor: Madiha Afzal, Uzma Aziz, Asma Yasin, Attka Maryam, Nosheen Khurram, Hina Zubair

Publikováno v: Pakistan Journal of Medical and Health Sciences. 16:174-176

Background: Unexplained 3rd trimester oligohydramnios is associated with adverse pregnancy outcomes if not treated appropriately. We conducted this study to evaluate the role of parenteral amino acids to improve amniotic fluid volume in idiopathic ol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::872d491d886e8f26ca448ade2e102958
https://doi.org/10.53350/pjmhs22164174

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