Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Hin-Koon Woo"'
Autor:
Danielle B Ulanet, Kiley Couto, Abhishek Jha, Sung Choe, Amanda Wang, Hin-Koon Woo, Mya Steadman, Byron DeLaBarre, Stefan Gross, Edward Driggers, Marion Dorsch, Jonathan B Hurov
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e115144 (2014)
Recent work has highlighted glutaminase (GLS) as a key player in cancer cell metabolism, providing glutamine-derived carbon and nitrogen to pathways that support proliferation. There is significant interest in targeting GLS for cancer therapy, althou
Externí odkaz:
https://doaj.org/article/0bc829c77b264c57a2de6ffb300eab3c
Publikováno v:
Journal of Chemical Physics; 8/1/2005, Vol. 123 Issue 5, p051106, 4p, 3 Graphs
Autor:
Shinsan M. Su, Shunqi Yan, Ed Driggers, Wentao Wei, Cheng Fang, Shengfang Jin, Jeff Hixon, Yi Gao, Giovanni Cianchetta, Francesco G. Salituro, Lewis C. Cantley, Kevin Qian, Fan Jiang, Sung Choe, Kaiko Kunii, Matthew G. Vander Heiden, Shalini Sethumadhavan, Erin Murphy, Katharine E. Yen, Stuart Murray, Hin Koon Woo, Charles Kung, Jeffrey O. Saunders, Shaohui Wang, Xiling Wang, Wei Liu, Lenny Dang, Kevin Marks, Byron DeLaBarre, Stefan Gross, Hua Yang
Publikováno v:
Chemistry & Biology. 19(9):1187-1198
SummaryProliferating tumor cells use aerobic glycolysis to support their high metabolic demands. Paradoxically, increased glycolysis is often accompanied by expression of the lower activity PKM2 isoform, effectively constraining lower glycolysis. Her
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::606aa052e44f56bf326011d5541703c7
Autor:
Forbes D. Porter, Leah P. Shriver, Gary J. Patti, Hin-Koon Woo, Christopher A. Wassif, Marianne Manchester, Jon Apon, Wilasinee Uritboonthai, Gary Siuzdak
Publikováno v:
Neuroscience. 170:858-864
Cholesterol is an essential component of cellular membranes that is required for normal lipid organization and cell signaling. While the mechanisms associated with maintaining cholesterol homeostasis in the plasma and peripheral tissues have been wel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85f134668a47d5f24a096540150be749
https://doi.org/10.1016/j.neuroscience.2010.07.038
https://doi.org/10.1016/j.neuroscience.2010.07.038
Autor:
Linh Hoang, Gary Siuzdak, Sunia A. Trauger, Eden P. Go, Trent R. Northen, Hin-Koon Woo, Benjamin P. Bowen
Publikováno v:
Rapid Communications in Mass Spectrometry. 23:1849-1855
Mass spectrometry has become an indispensable tool for the global study of metabolites (metabolomics), primarily using electrospray ionization mass spectrometry (ESI-MS). However, many important classes of molecules such as neutral lipids do not ioni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d265944419481b023a9fa00715f0cf43
https://doi.org/10.1002/rcm.4076
https://doi.org/10.1002/rcm.4076
Autor:
Leah Shriver, Rick C. Steenwyk, Marianne Manchester, Mayra N. Estrada, Oscar Yanes, Michael J. Potchoiba, Jon Apon, Stacey R. Oppenheimer, Hin-Koon Woo, Trent R. Northen, Gary Siuzdak
Publikováno v:
Analytical Chemistry. 81:2969-2975
Nanostructure initiator mass spectrometry (NIMS) is a recently introduced matrix-free desorption/ionization platform that requires minimal sample preparation. Its application to xenobiotics and endogenous metabolites in tissues is demonstrated, where
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac0d121beff3ec41ece94fa8726f134e
https://doi.org/10.1021/ac802576q
https://doi.org/10.1021/ac802576q
Autor:
Gary Siuzdak, Anders Nordström, Winnie Uritboonthail, Hin-Koon Woo, Kimberly L. Turner, Michael T. Northen, Trent R. Northen
Publikováno v:
Journal of the American Society for Mass Spectrometry. 18:1945-1949
The surface structure of porous silicon used in desorption/ionization on porous silicon (DIOS) mass analysis is known to play a primary role in the desorption/ionization (D/I) process. In this study, mass spectrometry and scanning electron microscopy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf711e709cc561faef36a1a73fa8ca11
https://doi.org/10.1016/j.jasms.2007.08.009
https://doi.org/10.1016/j.jasms.2007.08.009
Publikováno v:
The Journal of Physical Chemistry C. 111:17684-17689
Photoelectron spectroscopy of vibrationally cold singly and doubly charged higher fullerenes, Cn- and Cn2- (n = 76, 78, and 84), has been investigated at several photon energies. Vibrationally resolved spectra are obtained for both the singly and dou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::64708de46629c5eb02cfcf210427cf65
https://doi.org/10.1021/jp0703861
https://doi.org/10.1021/jp0703861
Publikováno v:
The Journal of Physical Chemistry A. 110:12603-12606
The cysteine anion was produced in the gas phase by electrospray ionization and investigated by photoelectron spectroscopy at low temperature (70 K). The cysteine anion was found to exhibit the thiolate form [ - SCH2CH(NH2)CO2H], rather than the expe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3c4d7482d38d6a39e0c23cd0a2ecdaf
https://doi.org/10.1021/jp0643799
https://doi.org/10.1021/jp0643799
Publikováno v:
Chemical Physics. 329:230-238
Two doubly charged transition metal complexes, Pt ( CN ) 4 2 - and Pt ( CN ) 6 2 - commonly found in the condensed phases, are produced as isolated species from solutions to the gas phase using electrospray ionization. Their stability and electronic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0ee4c7b22da28626df8605bb9e089b9d
https://doi.org/10.1016/j.chemphys.2006.07.018
https://doi.org/10.1016/j.chemphys.2006.07.018