Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Hin-Ching Lo"'
Autor:
Hai Wang, Lin Tian, Amit Goldstein, Jun Liu, Hin-Ching Lo, Kuanwei Sheng, Thomas Welte, Stephen T.C. Wong, Zbigniew Gugala, Fabio Stossi, Chenghang Zong, Zonghai Li, Michael A. Mancini, Xiang H.-F. Zhang
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
The bone microenvironment may alter therapeutic responses of disseminated breast cancer cells. Here the authors establish anex vivobone metastasis model, termed BICA, to delineate the effects of bone microenvironment and to rapidly discover anti-meta
Externí odkaz:
https://doaj.org/article/277b6262d22942908dfbeb83711138c3
Autor:
Meghana V. Trivedi, Rachel Schiff, Massimo Cristofanilli, Xiang H. Zhang, Sabino De Placido, Grazia Arpino, Hin Ching Lo, Anum Shaikh, Mario Giuliano
pub fee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::210e6e623049e0bf9c82970327206c7b
https://doi.org/10.1158/0008-5472.22420281
https://doi.org/10.1158/0008-5472.22420281
Autor:
Meghana V. Trivedi, Rachel Schiff, Massimo Cristofanilli, Xiang H. Zhang, Sabino De Placido, Grazia Arpino, Hin Ching Lo, Anum Shaikh, Mario Giuliano
Circulating tumor cell (CTC) clusters may represent one of the key mechanisms initiating the metastasis process. However, the series of pathophysiologic events by which CTC clusters originate, enter the circulation, and reach the distant sites remain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2435bb34449d93c91e7373e6576efcb7
https://doi.org/10.1158/0008-5472.c.6510606
https://doi.org/10.1158/0008-5472.c.6510606
Autor:
Franklin Gu, Jun O. Liu, Yang Gao, James M. Arnold, Jian He, Ik Sun Kim, Michael J. Toneff, Thomas Welte, Xiang Zhang, Yichi Niu, Kimberly Walker, Deborah Jebakumar, Jeffrey M. Rosen, Arun Sreekumar, Kuanwei Sheng, Yi Li, Igor Bado, Tuan M. Nguyen, Mahnaz Janghorban, Wen Bu, Amit Goldstein, Qianxing Mo, Arundhati Rao, Na Zhao, Chenghang Zong, Thomas F. Westbrook, Hin Ching Lo, Weiyu Jiang, Hai Wang
Publikováno v:
Nature cell biology
Cancer-induced immune responses affect tumor progression and therapeutic response. In multiple murine models and clinical datasets, we identified large variations of neutrophils and macrophages, which define “immune subtypes” of triple negative b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::660476a4e018f1f195169cbcf93a42a8
https://doi.org/10.1038/s41556-019-0373-7
https://doi.org/10.1038/s41556-019-0373-7
Autor:
Xiang Zhang, Jingyuan Hu, Yi Li, Weijie Zhang, Jun Liu, Swarnima Singh, Muchun Niu, Hin Ching Lo, Weiyu Jiang, Hai Wang, Zhan Xu, Igor Bado
SUMMARYMetastasis has been considered as the terminal step of tumor progression. However, recent clinical studies suggest that many metastases are seeded from other metastases, rather than primary tumors. Thus, some metastases can further spread, but
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c496f877d18bc0b0b0a633e3ea73d20d
https://doi.org/10.1101/2020.11.16.383828
https://doi.org/10.1101/2020.11.16.383828
Autor:
Poonam Sarkar, Luge Li, Hin Ching Lo, Haichao Wang, Ying Wooi Wan, Ik Sun Kim, Xiang Zhang, Zbigniew Gugala, Jingjing Liu, Rachel Schiff, Igor Bado, Amit Goldstein, Zhichun Xu, Shixia H, Matthew J. Ellis, Purba Singh, Zhuyun Liu, Wan-Jung Wu, Wen Zhang, Mahnaz Janghorban, Hyun-Hwan Jeong, Jingyuan Hu, Swarnima Singh, Muscallera A, Waleed Gm
SummaryER+ breast cancer exhibits a strong bone-tropism in metastasis. How the bone microenvironment impacts the ER signaling and endocrine therapies remains poorly understood. Here, we discover that the osteogenic niche transiently reduces ER expres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6ffee313876c85c424119714fbcc4487
https://doi.org/10.1101/2020.11.14.383000
https://doi.org/10.1101/2020.11.14.383000
Autor:
Yassine Rechoum, Jin-Ah Kim, Shunqiang Li, Sarah Herzog, Filip Janku, David Edwards, Gordon B. Mills, Helen J. Huang, W. Fraser Symmans, Charles E. Foulds, Luca Gelsomino, Suzanne A. W. Fuqua, Cristian Coarfa, Sandra L. Grimm, Lili Du, Meng Gao, Xiang Zhang, Susan G. Hilsenbeck, Hin Ching Lo, Sebastiano Andò, Thomas Gonzalez, Lin Tian, Alyssa Alaniz, Amanda Beyer, Guowei Gu, Dan Liu, Derek Dustin, Anna Tsimelzon, Natalie M. Fernandez, Jun Xu, Ralf Kittler
Publikováno v:
Oncogene
Estrogen receptor alpha gene (ESR1) mutations occur frequently in ER-positive metastatic breast cancer (MBC), and confer clinical resistance to aromatase inhibitors (AIs). Expression of the ESR1 Y537S mutation induced an epithelial-mesenchymal transi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c35a636238c069b7d49bd5fb192f55e0
https://pubmed.ncbi.nlm.nih.gov/34782721
https://pubmed.ncbi.nlm.nih.gov/34782721
Autor:
Meng Gao, Hin Ching Lo, Shunqiang Li, David Edwards, W. Fraser Symmans, Gordon B. Mills, Cristian Coarfa, Guowei Gu, Charles E. Foulds, Dan Liu, Alyssa Alaniz, Amanda Beyer, Sandra L. Grimm, Derek Dustin, Lili Du, Lin Tian, Anna Tsimelzon, Jin-Ah Kim, Helen J. Huang, Ralf Kittler, Sebastiano Andò, Susan G. Hilsenbeck, Luca Gelsomino, Suzanne A. W. Fuqua, Xiang Zhang, Jun Xu, Natalie M. Fernandez, Thomas Gonzalez, Yassine Rechoum, Sarah Herzog, Filip Janku
Publikováno v:
Oncogene. 41:460-460
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::80ce004ed5a6b939af17cea0a0944647
https://doi.org/10.1038/s41388-021-02104-w
https://doi.org/10.1038/s41388-021-02104-w
Autor:
Xiang Zhang, Hin Ching Lo
Publikováno v:
Developmental Cell. 45:663-665
The epithelial-to-mesenchymal transition (EMT) is a key driver of cancer metastasis. In this issue of Developmental Cell, Aiello et al. (2018) demonstrate that an EMT mechanism involving protein internalization impacts cell migration, while Reichert
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::03e58019d646974cbb50f3baeee94c2a
https://doi.org/10.1016/j.devcel.2018.05.033
https://doi.org/10.1016/j.devcel.2018.05.033
Autor:
Igor L, Bado, Weijie, Zhang, Jingyuan, Hu, Zhan, Xu, Hai, Wang, Poonam, Sarkar, Lucian, Li, Ying-Wooi, Wan, Jun, Liu, William, Wu, Hin Ching, Lo, Ik Sun, Kim, Swarnima, Singh, Mahnaz, Janghorban, Aaron M, Muscarella, Amit, Goldstein, Purba, Singh, Hyun-Hwan, Jeong, Chaozhong, Liu, Rachel, Schiff, Shixia, Huang, Matthew J, Ellis, M Waleed, Gaber, Zbigniew, Gugala, Zhandong, Liu, Xiang H-F, Zhang
Publikováno v:
Developmental cell. 56(8)
Estrogen receptor-positive (ER
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b8307f58d9e5377174ceb56951ae4028
https://pubmed.ncbi.nlm.nih.gov/33878297
https://pubmed.ncbi.nlm.nih.gov/33878297