Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Himavanth R. Gatla"'
Autor:
Sheetal Parida, Sumit Siddharth, Himavanth R. Gatla, Shaoguang Wu, Guannan Wang, Kathleen Gabrielson, Cynthia L. Sears, Brian H. Ladle, Dipali Sharma
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionObesity, an independent risk factor for breast cancer growth and metastatic progression, is also closely intertwined with gut dysbiosis; and both obese state and dysbiosis promote each other. Enteric abundance of Bacteroides fragilis is s
Externí odkaz:
https://doaj.org/article/d5bdc0018bcb483684d115d9a90c3c90
Publikováno v:
Biomolecules, Vol 5, Iss 1, Pp 223-243 (2015)
The increased expression of pro-inflammatory and pro-angiogenic chemokines contributes to ovarian cancer progression through the induction of tumor cell proliferation, survival, angiogenesis, and metastasis. The substantial potential of these chemoki
Externí odkaz:
https://doaj.org/article/1e4dcdaf0a3b47069a5efbb97ffd1ee2
Publikováno v:
Oncotarget
Although inhibitors of epigenetic regulators have been effective in the treatment of cutaneous T cell lymphoma (CTCL) and other hematopoietic malignancies, they have been less effective in solid tumors, including ovarian cancer (OC). We have previous
Autor:
Himavanth R. Gatla, Kartick C. Pramanik, Manoj K. Pandey, Monish Ram Makena, Dattesh Verlekar, Sahithi Sukhavasi
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 17, p 4242 (2019)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
Pancreatic ductal adenocarcinoma (PDAC) is responsible for 7.3% of all cancer deaths. Even though there is a steady increase in patient survival for most cancers over the decades, the patient survival rate for pancreatic cancer remains low with curre
Autor:
Zhe-Sheng Chen, Sai Aung Phyo, Atish Patel, Bipradeb Singha, Ivana Vancurova, Himavanth R. Gatla
Publikováno v:
Oncotarget
Ovarian cancer is associated with increased expression of the pro-angiogenic chemokine interleukin-8 (IL-8, CXCL8), which induces tumor cell proliferation, angiogenesis, and metastasis. Even though bortezomib (BZ) has shown remarkable anti-tumor acti
Autor:
Himavanth R. Gatla, Ales Vancura, Tzu-Pei Chang, Vladimir Poltoratsky, Shannon Sanacora, Ivana Vancurova, Subrata Manna, Bipradeb Singha
Publikováno v:
Journal of Biological Chemistry. 289:2687-2700
Proinflammatory and pro-angiogenic chemokine interleukin-8 (IL-8, CXCL8) contributes to ovarian cancer progression through its induction of tumor cell proliferation, survival, angiogenesis, and metastasis. Proteasome inhibition by bortezomib, which h
Autor:
Prashanth Thevkar, Siddhartha Yavvari, Nethaji Muniraj, Sahithi Sukhavasi, Monish Ram Makena, Himavanth R. Gatla
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 5, p 1110 (2019)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
Histone acetyltransferases (HATs) and histone deacetylases (HDACs) counteract with each other to regulate gene expression by altering chromatin structure. Aberrant HDAC activity was reported in many human diseases including wide range of cancers, vir
Autor:
Bipradeb Singha, Shannon Sanacora, Sitharam Ramaswami, Sai Aung Phyo, Himavanth R. Gatla, Tzu-Pei Chang, Ivana Vancurova, Subrata Manna
Publikováno v:
The Journal of Immunology. 191:2837-2846
Expression of the proinflammatory and proangiogenic chemokine IL-8, which is regulated at the transcriptional level by NF-κB, is constitutively increased in androgen-independent metastatic prostate cancer and correlates with poor prognosis. Inhibiti
Autor:
Ales Vancura, Bipradeb Singha, Yue Zou, Ivana Vancurova, Mohammad M. Uddin, Pengli Bu, Himavanth R. Gatla
Publikováno v:
The Journal of biological chemistry. 292(12)
Overexpression of the pro-angiogenic chemokine IL-8 (CXCL8) is associated with a poor prognosis in several solid tumors, including epithelial ovarian cancer (EOC). Even though histone deacetylase (HDAC) inhibition has shown remarkable antitumor activ
AMP-activated protein kinase (AMPK) is an energy sensor and master regulator of metabolism. AMPK functions as a fuel gauge monitoring systemic and cellular energy status. Activation of AMPK occurs when the intracellular AMP/ATP ratio increases and le
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66f7cad8f7d17c0da9717d16e1fc4373
https://europepmc.org/articles/PMC5122782/
https://europepmc.org/articles/PMC5122782/