Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Himanshu V Kothari"'
Publikováno v:
Atherosclerosis. 128:59-66
As a result of screening, several isoflavans were identified to be antagonists of cholesterol ester transfer protein (CETP) activity. The present study evaluates CGS 25159, a synthetic isoflavan, as a putative inhibitor of CETP activity of human and
Autor:
David Kritchevsky, Himanshu V. Kothari
Publikováno v:
Atherosclerosis. 31:371-375
The in vitro activity of cholesteryl ester hydrolase preparations of rat and rabbit aortas was assayed in the presence of the taurine and glycine conjugates of cholic, chenodeoxycholic, deoxycholic and lithocholic acids or in the presence of Triton X
Publikováno v:
Atherosclerosis. 19:459-462
Summary The cholesteryl ester synthesizing (S) and hydrolysing (H) activities of rabbit aorta have been assayed in rabbits fed an atherogenic regimen (2% cholesterol in 6% corn oil). Both synthesis and hydrolysis of cholesteryl esters increase over c
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism. 921:502-511
Sodium diclofenac, a potent cyclooxygenase inhibitor, was recently shown to inhibit arachidonic acid conversion to leukotriene products in human leukocytes. This activity was confirmed by radioimmunoassay in calcium ionophore A 23187-stimulated leuko
Publikováno v:
Experimental and Molecular Pathology. 10:288-294
Beta-glucuronidase activity is known to increase in human atherosclerotic arteries. Since beta-glucuronidase is a key marker enzyme for lysosomal activity, it was decided to investigate the activity of other lysosomal enzymes. In intima-media homogen
Publikováno v:
Journal of Labelled Compounds. 9:365-371
A simplified procedure is described for the synthesis and purification of labelled cholesteryl esters. The esters are synthesized enzymatically from (4-14C) cholesterol and free fatty acids. The separation of the lipids from aqueous medium is simplif
Autor:
David Kritchevsky, Himanshu V. Kothari
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism. 326:489-491
The aortic cholesterol esterase of pigeons of the Show Racer and White Carneau strains was studied using acetone dry powder preparations. The White Carneau pigeon is susceptible to atherosclerosis and its ratio of aortic cholesterol ester synthesizin
Autor:
David Kritchevsky, Himanshu V. Kothari
Publikováno v:
Atherosclerosis III ISBN: 9783642659560
The enzymes of lipid, carbohydrate, protein and nucleic acid metabolism in normal and arteriosclerotic aorta have been studied (Kirk, 1963). In a survey of enzyme activities, Kirk (1969) pointed out that aortic enzymic activity could not be directly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a078561e3300a4ced52851cdb9a079b4
https://doi.org/10.1007/978-3-642-65954-6_3
https://doi.org/10.1007/978-3-642-65954-6_3
Publikováno v:
Seminars in arthritis and rheumatism. 15(2 Suppl 1)
Evidence has been presented that inhibition by diclofenac sodium of the production of leukotrienes by cells participating in the inflammatory process is due to a decreased availability of intracellular arachidonic acid which results from enhanced upt
Autor:
David Kritchevsky, Himanshu V. Kothari
Publisher Summary This chapter discusses arterial enzymes of cholesteryl ester metabolism. The atherosclerotic plaque is characterized by lipid accumulation and a variable connective-tissue reaction. The important feature of atheroma lipids is the pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::23c2aa7c8c4ec4343ea9c2efa943da2b
https://doi.org/10.1016/b978-0-12-024916-9.50010-x
https://doi.org/10.1016/b978-0-12-024916-9.50010-x