Zobrazeno 1 - 10
of 81
pro vyhledávání: '"Himangshu S Bose"'
Autor:
Himangshu S Bose, Alan M Rice, Brendan Marshall, Fadi Gebrail, David Kupshik, Elizabeth W Perry
Publikováno v:
Endocrinology, Diabetes & Metabolism Case Reports, Vol 1, Iss 1, Pp 1-7 (2019)
Steroid hormones are essential for the survival of all mammals. In adrenal glands and gonads, cytochrome P450 side chain cleavage enzyme (SCC or CYP11A1), catalyzes conversion of cholesterol to pregnenolone. We studied a patient with ambiguous geni
Externí odkaz:
https://doaj.org/article/86376e331f2f491d8ce010b7969e1739
Publikováno v:
Endocrinology, Diabetes & Metabolism Case Reports, Vol 1, Iss 1, Pp 1-6 (2017)
Cholesterol transport into the mitochondria is required for synthesis of the first steroid, pregnenolone. Cholesterol is transported by the steroidogenic acute regulatory protein (STAR), which acts at the outer mitochondrial membrane prior to its imp
Externí odkaz:
https://doaj.org/article/547c47ef9a48439cab2e8540a0b3475a
Autor:
Himangshu S. Bose
Publikováno v:
iScience, Vol 27, Iss 6, Pp 110039- (2024)
Summary: Multiple metabolic events occur in mitochondria. Mitochondrial protein translocation from the cytoplasm across compartments depends on the amino acid sequence within the precursor. At the mitochondria associated-ER membrane, misfolding of a
Externí odkaz:
https://doaj.org/article/968f521c68304a32bc78b3ee5b4b93fd
Publikováno v:
iScience, Vol 26, Iss 4, Pp 106386- (2023)
Summary: Cholesterol initiates steroid metabolism in adrenal and gonadal mitochondria, which is essential for all mammalian survival. During stress an increased cholesterol transport rapidly increases steroidogenesis; however, the mechanism of mitoch
Externí odkaz:
https://doaj.org/article/81c6782f449f4a3eac5c30acce7486e4
Autor:
Himangshu S. Bose, Nicole E. Doetch
Publikováno v:
STAR Protocols, Vol 4, Iss 1, Pp 101996- (2023)
Summary: Mitochondria electron transport chain (ETC) complex II is essential for steroid metabolism. Here, we present a protocol to measure the stability and activity of mitochondria ETC complex II. We first describe mitochondria isolation from cell
Externí odkaz:
https://doaj.org/article/65b74854ebd54ef7bad71d811afeea6a
Autor:
Mahdieh Soveizi, Nejat Mahdieh, Aria Setoodeh, Fatemeh Sayarifard, Farzaneh Abbasi, Himangshu S. Bose, Bahareh Rabbani, Ali Rabbani
Publikováno v:
International Journal of Endocrinology, Vol 2020 (2020)
Premature pubarche (PP) is the appearance of sexual hair in children before puberty. The PP phenotype may attribute to nonclassic congenital adrenal hyperplasia (NC-CAH). In this study, we investigated the role of CYP21A2 gene variants in patients wi
Externí odkaz:
https://doaj.org/article/844d86afe4b9423ab70c051cb8a1d006
Autor:
Nejat Mahdieh, Himangshu S. Bose, Mahdieh Soveizi, Aria Setoodeh, Ali Rabbani, Bahareh Rabbani, Fatemeh Sayarifard, Farzaneh Abbasi
Publikováno v:
International Journal of Endocrinology, Vol 2020 (2020)
Premature pubarche (PP) is the appearance of sexual hair in children before puberty. The PP phenotype may attribute to nonclassic congenital adrenal hyperplasia (NC-CAH). In this study, we investigated the role of CYP21A2 gene variants in patients wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1d14b6c013029142d3fbe9f4104feef
https://doi.org/10.1155/2020/4329791
https://doi.org/10.1155/2020/4329791
Autor:
Ning-Ping Wang, Zhi-Qing Zhao, Feng Bai, Joshua Robert Eskew, Himangshu S. Bose, Guang‐Zhao Yang
Publikováno v:
Advances in Bioscience and Biotechnology. 11:123-139
Angiotensin II (Ang II) is known to elicit cardiac fibrosis by activating the AT1 receptor and CD44 expression in the in vivo model. However, the cellular/molecular mechanisms underlying cardiac fibrosis are still not well understood. This study exam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a5cfc05f810a1a2bdebf71f78eabb20f
https://doi.org/10.4236/abb.2020.114010
https://doi.org/10.4236/abb.2020.114010
Autor:
Walter L. Miller, Himangshu S. Bose
Publikováno v:
Journal of Lipid Research, Vol 52, Iss 12, Pp 2111-2135 (2011)
Steroid hormones are made from cholesterol, primarily derived from lipoproteins that enter cells via receptor-mediated endocytosis. In endo-lysosomes, cholesterol is released from cholesterol esters by lysosomal acid lipase (LAL; disordered in Wolman
Externí odkaz:
https://doaj.org/article/533c3dc9d7b54c92946b8ebb60d29a55
Autor:
William E Burak, Himangshu S. Bose, Curtis E Lanier, Brian W Wheeler, Maheshinie Rajapaksha, Nicholas D Carbo, Elin M Hahn, Randy M. Whittal, Edward Perkins, Brendan Marshall, Elizabeth W Perry, Neal M Hall, Mikhail M Melomed
Publikováno v:
Mol Cell Biol
Estradiol is essential for the development of female sex characteristics and fertility. Postmenopausal women and breast cancer patients have high levels of estradiol. Aromatase catalyzes estradiol synthesis; however, the factors regulating aromatase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c14881120c67310d2d8bb9428818208d
https://doi.org/10.1128/mcb.00357-21
https://doi.org/10.1128/mcb.00357-21