Early life cancer and chemotherapy lead to cognitive deficits related to alterations in microglial-associated gene expression in prefrontal cortex

Autor: Laaker, Collin J., Cantelon, Claire, Davis, Alyshia B., Lloyd, Kelsey R., Agyeman, Nana, Hiltz, Adam R., Smith, Brittany L., Konsman, Jan Pieter, Reyes, Teresa M.

Publikováno v: In Brain Behavior and Immunity October 2023 113:176-188

Perinatal Morphine Exposure Leads to Sex-Dependent Executive Function Deficits and Microglial Changes in Mice.

Autor: Smith BL; Department of Pharmacology & Systems Physiology, University of Cincinnati, Cincinnati, Ohio 45267 smithb103@nku.edu., Guzman TA; Department of Pharmacology & Systems Physiology, University of Cincinnati, Cincinnati, Ohio 45267., Brendle AH; Department of Pharmacology & Systems Physiology, University of Cincinnati, Cincinnati, Ohio 45267.; College of Nursing, University of Cincinnati, Cincinnati, Ohio 45221., Laaker CJ; Department of Pharmacology & Systems Physiology, University of Cincinnati, Cincinnati, Ohio 45267.; Neuroscience Training Program, University of Wisconsin-Madison, Madison, Wisconsin 53705., Ford A; Department of Pharmacology & Systems Physiology, University of Cincinnati, Cincinnati, Ohio 45267., Hiltz AR; Department of Pharmacology & Systems Physiology, University of Cincinnati, Cincinnati, Ohio 45267., Zhao J; Clinical Mass Spectrometry Laboratory, Division of Pathology and Laboratory Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio 45229-3026., Setchell KDR; Clinical Mass Spectrometry Laboratory, Division of Pathology and Laboratory Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio 45229-3026.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267., Reyes TM; Department of Pharmacology & Systems Physiology, University of Cincinnati, Cincinnati, Ohio 45267.

Publikováno v: ENeuro [eNeuro] 2022 Oct 17; Vol. 9 (5). Date of Electronic Publication: 2022 Oct 17 (Print Publication: 2022).