Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Hiltunen, J. K. (J. Kalervo)"'
Autor:
Rahman, M. T. (M. Tanvir), Koski, M. K. (M. Kristian), Panecka-Hofman, J. (Joanna), Schmitz, W. (Werner), Kastaniotis, A. J. (Alexander J.), Wade, R. C. (Rebecca C.), Wierenga, R. K. (Rik K.), Hiltunen, J. K. (J. Kalervo), Autio, K. J. (Kaija J.)
Mitochondrial fatty acid synthesis (mtFAS) is essential for respiratory function. MtFAS generates the octanoic acid precursor for lipoic acid synthesis, but the role of longer fatty acid products has remained unclear. The structurally well-characteri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2423::78080e0f66ec8805cab379eec32d09bf
http://urn.fi/urn:nbn:fi-fe2023071390600
http://urn.fi/urn:nbn:fi-fe2023071390600
Autor:
Shvetsova, A. (Antonina), Masud, A. J. (Ali J.), Schneider, L. (Laura), Bergmann, U. (Ulrich), Monteuuis, G. (Geoffray), Miinalainen, I. J. (Ilkka J.), Hiltunen, J. K. (J. Kalervo), Kastaniotis, A. J. (Alexander J.)
Om45 is a major protein of the yeast’s outer mitochondrial membrane under respiratory conditions. However, the cellular role of the protein has remained obscure. Previously, deletion mutant phenotypes have not been found, and clear amino acid seque
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2423::88fc8d9c0e1d126b44f24b668050b032
http://urn.fi/urn:nbn:fi-fe2022013111302
http://urn.fi/urn:nbn:fi-fe2022013111302
Autor:
Pietikäinen, L. P. (Laura P.), Rahman, M. T. (M. Tanvir), Hiltunen, J. K. (J. Kalervo), Dieckmann, C. L. (Carol L.), Kastaniotis, A. J. (Alexander J.)
Background/Objectives: Lipoylation of 2-ketoacid dehydrogenases is essential for mitochondrial function in eukaryotes. While the basic principles of the lipoylation processes have been worked out, we still lack a thorough understanding of the details
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2423::3b64e32b9197360af8a05041d13695eb
http://urn.fi/urn:nbn:fi-fe202103046541
http://urn.fi/urn:nbn:fi-fe202103046541
Autor:
Kangasniemi, M. H. (Marika H.), Haverinen, A. (Annina), Luiro, K. (Kaisu), Hiltunen, J. K. (J. Kalervo), Komsi, E. K. (Elina K.), Arffman, R. K. (Riikka K.), Heikinheimo, O. (Oskari), Tapanainen, J. S. (Juha S.), Piltonen, T. T. (Terhi T.)
Context: Combined oral contraceptives (COCs) alter inflammatory status and lipid metabolism. Whether different estrogens have different effects is poorly understood. Objective: We compared the effects of COCs containing ethinyl estradiol (EE) or estr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2423::44f2615707c09a0386c6471ab59f22ed
http://urn.fi/urn:nbn:fi-fe2021113058010
http://urn.fi/urn:nbn:fi-fe2021113058010
Autor:
Sridhar, S. (Shruthi), Schmitz, W. (Werner), Hiltunen, J. K. (J. Kalervo), Venkatesan, R. (Rajaram), Bergmann, U. (Uli), Kiema, T.-R. (Tiila-Riikka), Wierenga, R. K. (Rik K.)
The peroxisomal multifunctional enzyme type 1 (MFE1) catalyzes two successive reactions in the β-oxidation cycle: the 2E-enoyl-CoA hydratase (ECH) and NAD⁺-dependent 3S-hydroxyacyl-CoA dehydrogenase (HAD) reactions. MFE1 is a monomeric enzyme that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2423::8281c095b602d70169f3e8f41beadebb
http://urn.fi/urn:nbn:fi-fe2020120899853
http://urn.fi/urn:nbn:fi-fe2020120899853
Autor:
Mäkelä, A. M. (Anne M.), Hohtola, E. (Esa), Miinalainen, I. J. (Ilkka J.), Autio, J. A. (Joonas A.), Schmitz, W. (Werner), Niemi, K. J. (Kalle J.), Hiltunen, J. K. (J. Kalervo), Autio, K. J. (Kaija J.)
A large number of studies have demonstrated significance of polyunsaturated fatty acids (PUFAs) for human health. However, many aspects on signals translating PUFA-sensing into body homeostasis have remained enigmatic. To shed light on PUFA physiolog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2423::fc5d7cceffa7f2ffbd33ed46f6a43211
http://urn.fi/urn:nbn:fi-fe2020042119518
http://urn.fi/urn:nbn:fi-fe2020042119518
Autor:
Masud, A. J. (Ali J.), Kastaniotis, A. J. (Alexander J.), Rahman, M. T. (M. Tanvir), Autio, K. J. (Kaija J.), Hiltunen, J. K. (J. Kalervo)
Acyl carrier protein (ACP) is a principal partner in the cytosolic and mitochondrial fatty acid synthesis (FAS) pathways. The active form holo-ACP serves as FAS platform, using its 4′-phosphopantetheine group to present covalently attached FAS inte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2423::61572d3ca14414524b756b93741d396e
http://urn.fi/urn:nbn:fi-fe202103046511
http://urn.fi/urn:nbn:fi-fe202103046511
Autor:
Nair, R. R. (Remya R.), Koivisto, H. (Henna), Jokivarsi, K. (Kimmo), Miinalainen, I. J. (Ilkka J.), Autio, K. J. (Kaija J.), Manninen, A. (Aki), Poutiainen, P. (Pekka), Tanila, H. (Heikki), Hiltunen, J. K. (J. Kalervo), Kastaniotis, A. J. (Alexander J.)
There has been a growing interest toward mitochondrial fatty acid synthesis (mtFAS) since the recent discovery of a neurodegenerative human disorder termed MEPAN (mitochondrial enoyl reductase protein associated neurodegeneration), which is caused by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2423::aa91cff1dd0db1faa10c462298d5d1e6
http://urn.fi/urn:nbn:fi-fe201901242904
http://urn.fi/urn:nbn:fi-fe201901242904
Autor:
Nair, R. R. (Remya R.), Kerätär, J. M. (Juha M.), Autio, K. J. (Kaija J.), Masud, A. J. (Ali J.), Finnilä, M. A. (Mikko A.J.), Autio-Harmainen, H. I. (Helena I.), Miinalainen, I. J. (Ilkka J.), Nieminen, P. A. (Pentti A.), Hiltunen, J. K. (J. Kalervo), Kastaniotis, A. J. (Alexander J.)
Mitochondrial fatty acid synthesis (mtFAS) is an underappreciated but highly conserved metabolic process, indispensable for mitochondrial respiration. It was recently reported that dysfunction of mtFAS causes childhood onset of dystonia and optic atr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2423::13333574623a641f67a55d5542fa0a95
http://urn.fi/urn:nbn:fi-fe2017121355804
http://urn.fi/urn:nbn:fi-fe2017121355804
Autor:
Shvetsova, A. N. (Antonina N.), Mennerich, D. (Daniela), Kerätär, J. M. (Juha M.), Hiltunen, J. K. (J. Kalervo), Kietzmann, T. (Thomas)
Mitochondria are the main consumers of molecular O₂ in a cell as well as an abundant source of reactive oxygen species (ROS). Both, molecular oxygen and ROS are powerful regulators of the hypoxia-inducible factor-1α-subunit (HIF-α). While a numbe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2423::9a0bfc178ede74a69d72b7ef4f511705
http://urn.fi/urn:nbn:fi-fe201706277484
http://urn.fi/urn:nbn:fi-fe201706277484