Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Hiltraud Hosser"'
Autor:
Roxana Cristina Popescu, Diana Iulia Savu, Miriam Bierbaum, Adriana Grbenicek, Frank Schneider, Hiltraud Hosser, Bogdan Ștefan Vasile, Ecaterina Andronescu, Frederik Wenz, Frank A. Giordano, Carsten Herskind, Marlon R. Veldwijk
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 13, p 6778 (2021)
In this study, we determined the potential of polyethylene glycol-encapsulated iron oxide nanoparticles (IONPCO) for the intracellular delivery of the chemotherapeutic doxorubicin (IONPDOX) to enhance the cytotoxic effects of ionizing radiation. The
Externí odkaz:
https://doaj.org/article/145028e68585429185cf205a629455e1
Autor:
Georg Hildenbrand, Philipp Metzler, Götz Pilarczyk, Vladimir Bobu, Wilhelm Kriz, Hiltraud Hosser, Jens Fleckenstein, Matthias Krufczik, Felix Bestvater, Frederik Wenz, Michael Hausmann
Publikováno v:
PLoS ONE, Vol 13, Iss 1, p e0190183 (2018)
Localization microscopy has shown to be capable of systematic investigations on the arrangement and counting of cellular uptake of gold nanoparticles (GNP) with nanometer resolution. In this article, we show that the application of specially modified
Externí odkaz:
https://doaj.org/article/d7627413ffd945108e322f3fa88279ec
Autor:
Adina Boldeiu, Carsten Herskind, Mihaela Temelie, Roxana Cristina Popescu, D. A. Iancu, Frederik Wenz, Diana Savu, Frank A. Giordano, Hiltraud Hosser, I. Dorobantu, Bogdan Stefan Vasile, M. Straticiuc, Marlon R. Veldwijk, Ecaterina Andronescu
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Scientific Reports
Scientific Reports
The purpose of this study was to construct and characterize iron oxide nanoparticles (IONPCO) for intracellular delivery of the anthracycline doxorubicin (DOX; IONPDOX) in order to induce tumor cell inactivation. More than 80% of the loaded drug was
Autor:
Frank Schneider, Carsten Herskind, Frank A. Giordano, Hiltraud Hosser, Frederik Wenz, Diana Savu, Miriam Bierbaum, Adriana Grbenicek, Marlon R. Veldwijk, Ecaterina Andronescu, Bogdan Ștefan Vasile, Roxana Cristina Popescu
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 13
International Journal of Molecular Sciences, Vol 22, Iss 6778, p 6778 (2021)
Volume 22
Issue 13
International Journal of Molecular Sciences, Vol 22, Iss 6778, p 6778 (2021)
In this study, we determined the potential of polyethylene glycol-encapsulated iron oxide nanoparticles (IONPCO) for the intracellular delivery of the chemotherapeutic doxorubicin (IONPDOX) to enhance the cytotoxic effects of ionizing radiation. The
Autor:
Georg Hildenbrand, Hiltraud Hosser, Anne Kirchner, Frederik Wenz, Carsten Herskind, Daniel Barzan, Michael Hausmann, Abin Biswas, Marlon R. Veldwijk, Nina Burger
Publikováno v:
Nanomedicine: Nanotechnology, Biology and Medicine. 10:1365-1373
Gold nanoparticles (GNP) enhance the absorbance of photons thereby increasing emission of Auger-/photoelectrons in the nm–μm range. Yet, a major disadvantage is their diameter-dependent cellular uptake with an optimum of ~ 50 nm which may not offe
Autor:
Hiltraud Hosser, I. Dorobantu, M.R. Veldwijk, Roxana Cristina Popescu, F. Wenz, Bogdan Stefan Vasile, Adina Boldeiu, Ecaterina Andronescu, Carsten Herskind, Diana Savu, Frank Schneider, Frank A. Giordano
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 105:E681
Autor:
Franziska Theilig, Wilhelm Kriz, Robert Koesters, Michel LeHir, Hiltraud Hosser, Nicolas Picard, Rolf Gebhardt, Brigitte Kaissling, Adam B. Glick, Brunhilde Hähnel, Hermann Josef Gröne
Publikováno v:
The American Journal of Pathology. 177:632-643
We recently showed in a tetracycline-controlled transgenic mouse model that overexpression of transforming growth factor (TGF)-beta1 in renal tubules induces widespread peritubular fibrosis and focal degeneration of nephrons. In the present study we
Autor:
Jürgen Floege, Wilhelm Kriz, Hiltraud Hosser, Bettina Kränzlin, Norbert Gretz, Tammo Ostendorf, Bruni Hähnel, Fujio Shimizu, Soeren A. Gaertner
Publikováno v:
Journal of the American Society of Nephrology. 14:1904-1926
The present histopathologic study of anti-Thy-1.1 models of mesangioproliferative glomerulonephritis in rats provides a structural analysis of damage development and of pathways to recovery and to nephron loss. As long as the disease remains confined
Autor:
Hiltraud Hosser, Bettina Kränzlin, Wilhelm Kriz, Norbert Gretz, Brunhilde Hähnel, Marlies Elger, Abraham P. Provoost
Publikováno v:
Kidney and Blood Pressure Research. 22:26-36
Severe podocyte damage including detachment from the GBM leads to adhesion of the glomerular tuft to Bowman’s capsule, thus to a local loss of the separation of the tuft from the interstitium. Perfused capillaries contained in the tuft adhesion del
Autor:
Milena Traykova-Brauch, Hermann Josef Gröne, Brunhilde Hähnel, Wilhelm Kriz, Hiltraud Hosser, Marcus J. Moeller, Brigitte Kaissling, Robert Koesters, Samy Hakroush, Franziska Theilig, Tjeerd P. Sijmonsma, Ann L. Akeson, Manfred Jugold
Publikováno v:
The American journal of pathology. 175(5)
The role of vascular endothelial growth factor (VEGF) in renal fibrosis, tubular cyst formation, and glomerular diseases is incompletely understood. We studied a new conditional transgenic mouse system [Pax8-rtTA/(tetO)(7)VEGF], which allows increase