Decreased spinal cord motor neuron numbers in mice depleted of central nervous system copper.

Autor: Liddell JR; Department of Anatomy and Physiology, The University of Melbourne, Parkville, VIC 3010, Australia., Hilton JBW; Department of Anatomy and Physiology, The University of Melbourne, Parkville, VIC 3010, Australia., Wang YJ; Department of Anatomy and Physiology, The University of Melbourne, Parkville, VIC 3010, Australia., Billings JL; Department of Anatomy and Physiology, The University of Melbourne, Parkville, VIC 3010, Australia., Nikseresht S; Department of Anatomy and Physiology, The University of Melbourne, Parkville, VIC 3010, Australia., Kysenius K; Department of Anatomy and Physiology, The University of Melbourne, Parkville, VIC 3010, Australia., Fuller-Jackson JP; Department of Anatomy and Physiology, The University of Melbourne, Parkville, VIC 3010, Australia., Hare DJ; Atomic Medicine Initiative, University of Technology Sydney, Sydney, NSW 2007, Australia., Crouch PJ; Department of Anatomy and Physiology, The University of Melbourne, Parkville, VIC 3010, Australia.

Publikováno v: Metallomics : integrated biometal science [Metallomics] 2024 Sep 05; Vol. 16 (9).

Evidence for disrupted copper availability in human spinal cord supports Cu ^II (atsm) as a treatment option for sporadic cases of ALS.

Autor: Hilton JBW; Department of Anatomy and Physiology, The University of Melbourne, Victoria, 3010, Australia., Kysenius K; Department of Anatomy and Physiology, The University of Melbourne, Victoria, 3010, Australia., Liddell JR; Department of Anatomy and Physiology, The University of Melbourne, Victoria, 3010, Australia., Mercer SW; Department of Anatomy and Physiology, The University of Melbourne, Victoria, 3010, Australia., Paul B; School of Geography, Earth and Atmospheric Sciences, The University of Melbourne, Victoria, 3010, Australia.; Elemental Scientific Lasers, LLC, 685 Old Buffalo Trail, Bozeman, MT, 59715, USA., Beckman JS; Linus Pauling Institute and Department of Biochemistry and Biophysics, Oregon State University, Corvallis, OR, 97331, USA., McLean CA; Department of Anatomical Pathology, The Alfred Hospital, Victoria, 3004, Australia., White AR; Mental Health Program, Department of Cell and Molecular Biology, Queensland Institute of Biomedical Research Berghofer, Herston, QLD, 4006, Australia., Donnelly PS; School of Chemistry and Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Victoria, 3010, Australia., Bush AI; Melbourne Dementia Research Centre, The University of Melbourne and Florey Institute of Neuroscience and Mental Health, Victoria, 3010, Australia., Hare DJ; Atomic Medicine Initiative, University of Technology Sydney, Ultimo, NSW, 2007, Australia., Roberts BR; Department of Biochemistry, Emory University School of Medicine, Atlanta, GA, 30322, USA., Crouch PJ; Department of Anatomy and Physiology, The University of Melbourne, Victoria, 3010, Australia. pjcrouch@unimelb.edu.au.

Publikováno v: Scientific reports [Sci Rep] 2024 Mar 11; Vol. 14 (1), pp. 5929. Date of Electronic Publication: 2024 Mar 11.

Evidence for decreased copper associated with demyelination in the corpus callosum of cuprizone-treated mice.

Autor: Hilton JBW; Department of Anatomy & Physiology, The University of Melbourne, Victoria 3010, Australia., Kysenius K; Department of Anatomy & Physiology, The University of Melbourne, Victoria 3010, Australia.; Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Victoria 3010, Australia., Liddell JR; Department of Anatomy & Physiology, The University of Melbourne, Victoria 3010, Australia., Mercer SW; Department of Anatomy & Physiology, The University of Melbourne, Victoria 3010, Australia., Hare DJ; Atomic Medicine Initiative, University of Technology Sydney, Sydney, New South Wales 2007, Australia., Buncic G; School of Chemistry and Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Victoria 3010, Australia., Paul B; School of Earth Sciences, The University of Melbourne, Victoria 3010, Australia., Wang Y; Department of Anatomy & Physiology, The University of Melbourne, Victoria 3010, Australia., Murray SS; Department of Anatomy & Physiology, The University of Melbourne, Victoria 3010, Australia.; Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Victoria 3010, Australia., Kilpatrick TJ; Department of Anatomy & Physiology, The University of Melbourne, Victoria 3010, Australia.; Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Victoria 3010, Australia., White AR; Queensland Institute of Medical Research Berghofer, Herston, Queensland 4006, Australia., Donnelly PS; School of Chemistry and Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Victoria 3010, Australia., Crouch PJ; Department of Anatomy & Physiology, The University of Melbourne, Victoria 3010, Australia.

Publikováno v: Metallomics : integrated biometal science [Metallomics] 2024 Jan 05; Vol. 16 (1).

Cu ^II (atsm) significantly decreases microglial reactivity in patients with sporadic amyotrophic lateral sclerosis.

Autor: Liddell JR; Department of Anatomy and Physiology, The University of Melbourne, Parkville, Victoria, Australia., Hilton JBW; Department of Anatomy and Physiology, The University of Melbourne, Parkville, Victoria, Australia., Crouch PJ; Department of Anatomy and Physiology, The University of Melbourne, Parkville, Victoria, Australia.

Publikováno v: Neuropathology and applied neurobiology [Neuropathol Appl Neurobiol] 2023 Oct; Vol. 49 (5), pp. e12938.

Proteome-wide systems genetics identifies UFMylation as a regulator of skeletal muscle function.

Autor: Molendijk J; Department of Anatomy and Physiology, University of Melbourne, Melbourne, Australia.; Centre for Muscle Research, University of Melbourne, Melbourne, Australia., Blazev R; Department of Anatomy and Physiology, University of Melbourne, Melbourne, Australia.; Centre for Muscle Research, University of Melbourne, Melbourne, Australia., Mills RJ; QIMR Berghofer Medical Research Institute, Brisbane, Australia., Ng YK; Department of Anatomy and Physiology, University of Melbourne, Melbourne, Australia.; Centre for Muscle Research, University of Melbourne, Melbourne, Australia., Watt KI; Department of Anatomy and Physiology, University of Melbourne, Melbourne, Australia.; Centre for Muscle Research, University of Melbourne, Melbourne, Australia., Chau D; Department of Biological Chemistry and Center for Epigenetics and Metabolism, University of California, Irvine, Irvine, United States., Gregorevic P; Department of Anatomy and Physiology, University of Melbourne, Melbourne, Australia.; Centre for Muscle Research, University of Melbourne, Melbourne, Australia., Crouch PJ; Department of Biochemistry and Pharmacology, University of Melbourne, Melbourne, Australia., Hilton JBW; Department of Biochemistry and Pharmacology, University of Melbourne, Melbourne, Australia., Lisowski L; Children's Medical Research Institute, University of Sydney, Sydney, Australia.; Military Institute of Medicine, Warszawa, Poland., Zhang P; Department of Human Genetics/Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, United States., Reue K; Department of Human Genetics/Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, United States., Lusis AJ; Department of Human Genetics/Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, United States.; Department of Microbiology, Immunology and Molecular Genetics, University of California, Los Angeles, Los Angeles, United States., Hudson JE; QIMR Berghofer Medical Research Institute, Brisbane, Australia., James DE; Charles Perkins Centre, School of Life and Environmental Science, School of Medical Science, University of Sydney, Sydney, Australia., Seldin MM; Department of Biological Chemistry and Center for Epigenetics and Metabolism, University of California, Irvine, Irvine, United States., Parker BL; Department of Anatomy and Physiology, University of Melbourne, Melbourne, Australia.; Centre for Muscle Research, University of Melbourne, Melbourne, Australia.

Publikováno v: ELife [Elife] 2022 Dec 06; Vol. 11. Date of Electronic Publication: 2022 Dec 06.