Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Hilton A. Salhanick"'
Autor:
Hilton A. Salhanick
The Center for Population Research of the National Institute of Child Health and Human Development began operations in August 1968 and is engaged in research dealing with health-related popula tion problems. We organize and support projects for the
Publikováno v:
Endocrine Reviews. 16:682-683
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::72f69275a5c9ba7412455465307939d4
https://doi.org/10.1210/edrv-16-5-682
https://doi.org/10.1210/edrv-16-5-682
Publikováno v:
Steroids. 37:673-680
Potent inhibitors of cholesterol side chain cleavage were tested for inhibition of 11 beta-hydroxylation of 11-deoxycortisol by bovine adrenal cortex mitochondria. Compounds which inhibited 11 beta-hydroxylation were metyrapone, 4-phenylimidazole, 1-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1286626e3a14bac87e4ea6512704205
https://doi.org/10.1016/s0039-128x(81)90209-9
https://doi.org/10.1016/s0039-128x(81)90209-9
Autor:
Richard C. Cabot, Robert E. Scully, James J. Galdabini, Betty U. McNeely, Hilton A. Salhanick, Jaime Prat
Publikováno v:
New England Journal of Medicine. 301:318-323
Presentation of Case A 24-year-old woman was admitted to the hospital because of virilization. At the age of nine years she had an illness characterized by anorexia, hepatic enlargement, jaundice a...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2f894f906d16659a125cbc93289518b2
https://doi.org/10.1056/nejm197908093010608
https://doi.org/10.1056/nejm197908093010608
Publikováno v:
Endocrinology. 103:1605-1610
The luteolytic potency of D- and L-aminoglutethimide (D- and L-AG) was compared in in vivo assays in the rat and rabbit. By assay of plasma progesterone depletion in the rabbit, the potency of L-AG relative to D-AG was 0.21. By the plasma procedure i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a13eb8d097cfc194cda66e687860796
https://doi.org/10.1210/endo-103-5-1605
https://doi.org/10.1210/endo-103-5-1605
Publikováno v:
Endocrinology. 101:89-92
Because aminoglutethimide is a potentially important drug in the treatment of certain malignancies as well as fertility control, its stereoisomers were studied for binding to corpus luteum mitochondrial cytochrome P-450 and inhibition of cholesterol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cfcd9d4870212484b7507c6dd9ec9e28
https://doi.org/10.1210/endo-101-1-89
https://doi.org/10.1210/endo-101-1-89
Publikováno v:
Biochemistry. 16:593-600
Absorbance changes in the spectrum of cytochrome P-450 were related to the inhibition of [26-14C]cholesterol oxidation to [14C]isocaproate and pregnenolone in mitochondria from bovine corpus luteum produced by two types of ligands. Nitrogenous inhibi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::734c5eede5d2650020ced4bfcbccb090
https://doi.org/10.1021/bi00623a006
https://doi.org/10.1021/bi00623a006
Publikováno v:
Biochemical and Biophysical Research Communications. 105:110-116
Summary The amino acid composition of cytochrome P-450 SCC , purified from bovine corpus luteal mitochondria was determined and expressed on the basis of the molecular weight 48,000, determined by SDS gel electrophoresis. The composition was similar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95e2542925d28c64b319978fead23c35
https://doi.org/10.1016/s0006-291x(82)80017-x
https://doi.org/10.1016/s0006-291x(82)80017-x
Autor:
V. I. Uzgiris, Kiyoko Kashiwagi, Hilton A. Salhanick, P. E. Graves, M. Querner, E. N. McIntosh
Publikováno v:
Endocrinology. 102:1077-1087
The inhibitory activity of cyanoketone (CNK; 2alpha-cyano-4,4,17alpha-trimethyl-17beta-hydroxy-5-androsten-3-one), was investigated for enzymes of the respiratory chain and cholesterol side chain cleavage (CSCC). In bovine corpus luteum mitochondria
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90d9bac9d2149be0360c4c82d11c8eb9
https://doi.org/10.1210/endo-102-4-1077
https://doi.org/10.1210/endo-102-4-1077
Publikováno v:
Biochemistry. 26:1270-1275
The intramolecular site of P-450scc for conversion of cholesterol to pregnenolone involves a substrate site, an active site, and a site for transmission of electrons. The substrate site was studied with a high-affinity, high-potency nitroxide spin-la
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9dc6240aaad4051de037e591e7cd10ee
https://doi.org/10.1021/bi00379a011
https://doi.org/10.1021/bi00379a011