Výsledky vyhledávání - "Hilton, I. B."

The Open Chromatin Landscape of Kaposi's Sarcoma-Associated Herpesvirus

Autor: Dittmer, D. P., Simon, J. M., Damania, B., Lieb, J. D., Hilton, I. B., Davis, I. J.

Kaposi's sarcoma-associated herpesvirus (KSHV) is an oncogenic gammaherpesvirus which establishes latent infection in endothelial and B cells, as well as in primary effusion lymphoma (PEL). During latency, the viral genome exists as a circular DNA mi

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Distinct p53, p53:LANA, and LANA Complexes in Kaposi's Sarcoma-Associated Herpesvirus Lymphomas

Autor: Chen, W., Hilton, I. B., Burd, C. E., Dittmer, D. P., Staudt, M. R.

The role of p53 in primary effusion lymphoma (PEL) is complicated. The latency-associated nuclear antigen (LANA) of Kaposi's sarcoma-associated herpesvirus (KSHV) binds p53. Despite this interaction, we had found that p53 was functional in PEL, i.e.,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8ab1d5ba29183075b96be0b9d45e64b0

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