Výsledky vyhledávání - "Hilton, I. B."

The Open Chromatin Landscape of Kaposi's Sarcoma-Associated Herpesvirus

Autor: Dittmer, D. P., Simon, J. M., Damania, B., Lieb, J. D., Hilton, I. B., Davis, I. J.

Kaposi's sarcoma-associated herpesvirus (KSHV) is an oncogenic gammaherpesvirus which establishes latent infection in endothelial and B cells, as well as in primary effusion lymphoma (PEL). During latency, the viral genome exists as a circular DNA mi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::81e31f7e05377e6cf451f42f72f73667

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Distinct p53, p53:LANA, and LANA Complexes in Kaposi's Sarcoma-Associated Herpesvirus Lymphomas

Autor: Chen, W., Hilton, I. B., Burd, C. E., Dittmer, D. P., Staudt, M. R.

The role of p53 in primary effusion lymphoma (PEL) is complicated. The latency-associated nuclear antigen (LANA) of Kaposi's sarcoma-associated herpesvirus (KSHV) binds p53. Despite this interaction, we had found that p53 was functional in PEL, i.e.,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8ab1d5ba29183075b96be0b9d45e64b0

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Akademický článek

Epigenome editing technologies for discovery and medicine.

Autor: McCutcheon SR; Department of Biomedical Engineering, Duke University, Durham, NC, USA.; Center for Advanced Genomic Technologies, Duke University, Durham, NC, USA., Rohm D; Department of Biomedical Engineering, Duke University, Durham, NC, USA.; Center for Advanced Genomic Technologies, Duke University, Durham, NC, USA., Iglesias N; Department of Biomedical Engineering, Duke University, Durham, NC, USA.; Center for Advanced Genomic Technologies, Duke University, Durham, NC, USA., Gersbach CA; Department of Biomedical Engineering, Duke University, Durham, NC, USA. charles.gersbach@duke.edu.; Center for Advanced Genomic Technologies, Duke University, Durham, NC, USA. charles.gersbach@duke.edu.

Publikováno v: Nature biotechnology [Nat Biotechnol] 2024 Aug; Vol. 42 (8), pp. 1199-1217. Date of Electronic Publication: 2024 Jul 29.

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Akademický článek

CRISPR technologies for genome, epigenome and transcriptome editing.

Autor: Villiger L; McGovern Institute for Brain Research, Massachusetts Institute of Technology Cambridge, Cambridge, MA, USA., Joung J; Whitehead Institute for Biomedical Research, Cambridge, MA, USA.; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA., Koblan L; Whitehead Institute for Biomedical Research, Cambridge, MA, USA.; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA., Weissman J; Whitehead Institute for Biomedical Research, Cambridge, MA, USA.; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA.; Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, MA, USA.; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA., Abudayyeh OO; McGovern Institute for Brain Research, Massachusetts Institute of Technology Cambridge, Cambridge, MA, USA. omar@abudayyeh.science., Gootenberg JS; McGovern Institute for Brain Research, Massachusetts Institute of Technology Cambridge, Cambridge, MA, USA. jgoot@mit.edu.

Publikováno v: Nature reviews. Molecular cell biology [Nat Rev Mol Cell Biol] 2024 Jun; Vol. 25 (6), pp. 464-487. Date of Electronic Publication: 2024 Feb 02.

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Akademický článek

Implanting mechanically reprogrammed fibroblasts for aged tissue regeneration and wound healing.

Autor: Roy, Bibhas¹ (AUTHOR), Pekec, Tina¹ (AUTHOR), Yuan, Luezhen^1,2 (AUTHOR), Shivashankar, G. V.^1,2 (AUTHOR) shiva.gvs@gmail.com

Publikováno v: Aging Cell. Feb2024, Vol. 23 Issue 2, p1-14. 14p.

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Application of Genome Editing for Crop Improvement.

Autor: Dinkar, Kumar, Anand, Dwivedi, Namrata, Kumar, Sanjay, Rani, Diksha, Sinha, Sima, Sharma, Kamal, Kumar, Rounak, Singh, P. K.

Publikováno v: Ecology, Environment & Conservation (0971765X); 2024 Supplement, Vol. 30, pS146-S162, 17p

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Akademický článek

Compact engineered human mechanosensitive transactivation modules enable potent and versatile synthetic transcriptional control.

Autor: Mahata B; Department of Bioengineering, Rice University, Houston, TX, USA., Cabrera A; Department of Bioengineering, Rice University, Houston, TX, USA., Brenner DA; Department of Bioengineering, Rice University, Houston, TX, USA., Guerra-Resendez RS; Systems, Synthetic, and Physical Biology Graduate Program, Rice University, Houston, TX, USA., Li J; Department of Bioengineering, Rice University, Houston, TX, USA., Goell J; Department of Bioengineering, Rice University, Houston, TX, USA., Wang K; Department of Bioengineering, Rice University, Houston, TX, USA., Guo Y; Department of Bioengineering, Rice University, Houston, TX, USA., Escobar M; Department of BioSciences, Rice University, Houston, TX, USA., Parthasarathy AK; Department of Bioengineering, Rice University, Houston, TX, USA., Szadowski H; Systems, Synthetic, and Physical Biology Graduate Program, Rice University, Houston, TX, USA., Bedford G; Department of Bioengineering, Rice University, Houston, TX, USA., Reed DR; Department of Bioengineering, Rice University, Houston, TX, USA., Kim S; Department of Bioengineering, Rice University, Houston, TX, USA., Hilton IB; Department of Bioengineering, Rice University, Houston, TX, USA. isaac.hilton@rice.edu.; Systems, Synthetic, and Physical Biology Graduate Program, Rice University, Houston, TX, USA. isaac.hilton@rice.edu.; Department of BioSciences, Rice University, Houston, TX, USA. isaac.hilton@rice.edu.

Publikováno v: Nature methods [Nat Methods] 2023 Nov; Vol. 20 (11), pp. 1716-1728. Date of Electronic Publication: 2023 Oct 09.

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