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pro vyhledávání: '"Hilmar Warenius"'
Autor:
Hilmar Warenius
Publikováno v:
Expert opinion on medical diagnostics. 3(4)
Although the term theranostics has been coined only fairly recently, attempts to relate the level of biomarkers to therapeutic response in the oncology clinic go back several decades. After a long period in which a limited number of individual theran
Autor:
Hilmar, Warenius, Amanda, Howarth, Laurence, Seabra, Leto, Kyritsi, Roisin, Dormer, Shanez, Anandappa, Carole, Thomas
Publikováno v:
Journal of experimental therapeuticsoncology. 7(3)
Tumour heterogeneity is becoming increasingly important as an obstacle to genomic and proteomic technologies designed to improve the diagnosis and treatment of human cancer. In a panel of 19 human in-vitro cancer cell lines, we show marked heterogene
Autor:
Shanez Anandappa, Carole Thomas, Roisin Dormer, Amanda Howarth, Ros White, Laurence Seabra, Lito Kyritsi, Hilmar Warenius
Publikováno v:
International journal of oncology. 32(4)
Despite major advances in the molecular biology of the cancer cell over the past two decades, the great majority of patients are still treated by conventional cytotoxic drugs. The chemotherapy regimens employed frequently include platinating agents,
Autor:
Hilmar Warenius, Laurence Seabra
Publikováno v:
European journal of cancer (Oxford, England : 1990). 43(9)
The roles of the cyclin-dependent kinases Cdk2, Cdk4 and Cdk6 and their complementary cyclin partners in moving cells from a quiescent state into active DNA synthesis are presently undergoing re-evaluation. Normal cell cycling now appears possible in
Autor:
Hilmar Warenius, Laurence Seabra, Jon W Essex, Richard I. Maurer, Jeremy P. Blaydes, Jeremy D. Kilburn, Usha Agarwala
Publikováno v:
Molecular Cancer
Molecular Cancer, Vol 10, Iss 1, p 72 (2011)
Molecular Cancer, Vol 10, Iss 1, p 72 (2011)
Background Cyclin-dependent kinases 2, 4 and 6 (Cdk2, Cdk4, Cdk6) are closely structurally homologous proteins which are classically understood to control the transition from the G1 to the S-phases of the cell cycle by combining with their appropriat
Autor:
Laurence Seabra, Hilmar Warenius
Publikováno v:
Gastroenterology. 124:A365
Autor:
Tracy Gorman, Philip S. Rudland, Hilmar Warenius, Roger Barraclough, C.M. Thompson, Matthew D. Jones, Mark Jones
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 36:242
Autor:
Laurence Seabra, Hilmar Warenius
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 32:235
Autor:
Hilmar Warenius, Karol Sikora
Publikováno v:
Medical Oncology and Tumor Pharmacotherapy. 3:5-9
We have examined the serological response in immunosuppressed mice bearing xenografts of the human colorectal carcinoma line HT29. The sera of such animals contain antibodies which bind to HT29 cell membrane components. This antibody activity was not